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Relationship Between RNF213 p.R4810K and Echocardiographic Findings in Patients with Cerebrovascular Diseases: A Multicenter Prospective Cohort Study

Journal of the American Heart Association

BackgroundRING finger protein 213 (RNF213) p.R4810K is an established risk factor for moyamoya disease and intracranial artery stenosis in East Asian people. Recent evidence suggests its potential association with extracranial cardiovascular diseases, including pulmonary hypertension.

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Thrombotic Thrombocytopenic Purpura: A Missed Cause in Stroke Prevention Guidelines

Stroke Journal

The 2024 Guidelines for the Primary Prevention of Stroke, recently updated by the American Heart Association and the American Stroke Association, serve as an essential resource for clinicians aiming to reduce the growing impact of cerebrovascular disease.

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Lipoprotein(a) as a risk factor for atherosclerotic cardiovascular disease in patients in non-metropolitan area of Brandenburg, Germany

Frontiers in Cardiovascular Medicine

Background and aims In the non-metropolitan region of Brandenburg (Germany), which is characterized by high rates of cardiovascular diseases and underserved medical care, there is a lack of awareness regarding lipoprotein(a) [Lp(a)] as a risk factor. 3.95, p  = 0.003). vs. 45.8%; 17.6% vs. 13.9%, p  = 0.001). vs. 45.8%; 17.6%

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Understanding the Relationship Between Cerebrovascular Disease and the Gut Microbiome

Stroke: Vascular and Interventional Neurology

While traditional vascular risk factors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies.

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Risk factors analysis and prediction model establishment of acute kidney injury after heart valve replacement in patients with normal renal function

Frontiers in Cardiovascular Medicine

The Lasso regression was used to preliminarily screen potential risk factors, which were entered into the multivariable logistic regression analysis to identify preoperative independent risk factors for postoperative AKI. Results220 patients (36.2%) developed AKI after surgery. and 63.4%, respectively.

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Gut microbiota: a potential new regulator of hypertension

Frontiers in Cardiovascular Medicine

Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and has become a global public health concern. Although hypertension results from a combination of factors, the specific mechanism is still unclear.

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A study of clinical and serological correlation of early myocardial injury in elderly patients infected with the Omicron variant

Frontiers in Cardiovascular Medicine

Introduction Myocardial injury in elderly Omicron variant patients is a leading cause of severe disease and death. This study focuses on elucidating the clinical characteristics and potential risk factors associated with myocardial injury in elderly patients infected with the Omicron variant.