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Understanding the Relationship Between Cerebrovascular Disease and the Gut Microbiome

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Ahead of Print. While traditional vascular risk factors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies.

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Abstract WP222: Basilar Artery Stenosis in Children With Moyamoya

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWP222-AWP222, February 1, 2024. Introduction:Moyamoya is a progressive cerebrovascular disease characterized by stenosis of the cerebral arteries in the anterior circulation and less often the posterior circulation. The median time from diagnosis was 0 years (IQR 0, 1.3).

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Abstract WP394: Homocysteine induces neurovascular injury and increases BBB permeability

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP394-AWP394, February 1, 2025. Background:Our recently reported that patent foramen ovale (PFO) shunt enables the elevation of total homocysteine (tHcy) in patients circulation (Deng, Neurology 2021). However, the underlying molecular mechanism of how tHcy causes PFO-related injury is unclear.

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Abstract 78: Evaluation of AneuScreenTM, a Blood-Based Gene Expression Diagnostic for Intracranial Aneurysm

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page A78-A78, February 1, 2025. Introduction:Intracranial aneurysm (IA), a cerebrovascular disease affecting 3-5% of US population, leads to subarachnoid hemorrage. This demonstrates the potential of using circulating blood to screen for IA presence.

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Abstract WMP108: Association of Circulating Markers of Inflammation to Baseline and Progression of Carotid Artery Intima-Media Thickness

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWMP108-AWMP108, February 1, 2024. Introduction:There is strong evidence of an association between systemic inflammation and ischemic stroke. One measure of subclinical atherosclerosis, carotid artery intima-media thickness (CIMT), is independently associated with ischemic stroke.

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

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Moyamoya Angiopathy and Antiphospholipid Antibodies: A Coincidental Association?

Stroke Journal

Stroke, Volume 56, Issue 1 , Page 190-193, January 1, 2025. The prevalence of transient ischemic attacks, ischemic stroke, and hemorrhagic stroke did not differ between patients with aPL-positive and aPL-negative MMA.CONCLUSIONS:The prevalence of aPL in patients with MMA is comparable to that in non-MMA controls.