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Impact of Smokeless Oral Nicotine Products on Cardiovascular Disease: Implications for Policy, Prevention, and Treatment: A Policy Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. The use of some types of these products, for instance, is associated with an increased mortality risk in those with ischemic heart or cerebrovascular disease.

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Understanding the Relationship Between Cerebrovascular Disease and the Gut Microbiome

Stroke: Vascular and Interventional Neurology

Among other potential contributors to atheroma formation and cerebrovascular disease, the gut microbiome has become increasingly implicated as a mediator of vascular risk. Several of these toxic metabolites, including trimethylamine and trimethylamine Noxide, have been extensively studied in cardiovascular and cerebrovascular disease.

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Abstract WP222: Basilar Artery Stenosis in Children With Moyamoya

Stroke Journal

Introduction:Moyamoya is a progressive cerebrovascular disease characterized by stenosis of the cerebral arteries in the anterior circulation and less often the posterior circulation. Stroke, Volume 55, Issue Suppl_1 , Page AWP222-AWP222, February 1, 2024. The median time from diagnosis was 0 years (IQR 0, 1.3).

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Abstract TP284: Transcriptome Profiling of Peripheral Blood Mononuclear Cells in Moyamoya Disease

Stroke Journal

Objectives:Moyamoya Disease (MMD) is a progressive occlusive cerebrovascular disease with unknown etiology and pathogenesis. Stroke, Volume 55, Issue Suppl_1 , Page ATP284-ATP284, February 1, 2024. Peripheral blood mononuclear cells (PBMCs) were isolated and cryopreserved.

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Abstract WP394: Homocysteine induces neurovascular injury and increases BBB permeability

Stroke Journal

Background:Our recently reported that patent foramen ovale (PFO) shunt enables the elevation of total homocysteine (tHcy) in patients circulation (Deng, Neurology 2021). Stroke, Volume 56, Issue Suppl_1 , Page AWP394-AWP394, February 1, 2025. However, the underlying molecular mechanism of how tHcy causes PFO-related injury is unclear.

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Abstract 78: Evaluation of AneuScreenTM, a Blood-Based Gene Expression Diagnostic for Intracranial Aneurysm

Stroke Journal

Introduction:Intracranial aneurysm (IA), a cerebrovascular disease affecting 3-5% of US population, leads to subarachnoid hemorrage. This demonstrates the potential of using circulating blood to screen for IA presence. Stroke, Volume 56, Issue Suppl_1 , Page A78-A78, February 1, 2025.

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3