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Researchers have uncovered novel insights into how brain function disruptions related to cerebrovasculardisease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.
Nonmalignant gynecological diseases (NMGD) are associated with cardiovascular and/or cerebrovasculardisease (C/CVD), according to a systematic review and meta-analysis published online in Heart.
A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new study.
We hypothesized that insidious abnormal cardiac functions are detected inRNF213p.R4810K carriers with cerebrovascular diseases.Methods and ResultsWe investigated patients registered in the National Cerebral and Cardiovascular Center Genome Registry between May 2017 and August 2021 who underwent echocardiography.
A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new UCLA Health study.
The use of some types of these products, for instance, is associated with an increased mortality risk in those with ischemic heart or cerebrovasculardisease. Smokeless oral nicotine products are addictive, and their use has potential adverse effects on some but not all biomarkers of cardiovascular risk.
Having one or more common gynecological disorders, such as endometriosis or heavy or irregular periods, may be linked to a heightened risk of heart disease and conditions that affect blood flow to the brain (cerebrovasculardisease), finds a pooled data analysis of the available evidence published online in the journal Heart.
The association between the stress hyperglycemia ratio (SHR), which represents the degree of acute stress hyperglycemic status, and the risk of mortality in cerebrovasculardisease patients in the intensive ca.
Among other potential contributors to atheroma formation and cerebrovasculardisease, the gut microbiome has become increasingly implicated as a mediator of vascular risk. Several of these toxic metabolites, including trimethylamine and trimethylamine Noxide, have been extensively studied in cardiovascular and cerebrovasculardisease.
The 2024 Guidelines for the Primary Prevention of Stroke, recently updated by the American Heart Association and the American Stroke Association, serve as an essential resource for clinicians aiming to reduce the growing impact of cerebrovasculardisease.
Our subgroup analysis revealed that mothers with a history of GDM faced various risks (20% to 2-fold) of developing different subtypes of CVDs, including cerebrovasculardisease, coronary artery disease, heart failure, and venous thromboembolism.
Early identification allows for timely initiation of guideline-directed medical therapy for secondary prevention of cardiovascular disease, cerebrovasculardisease, and limb events.
Accumulating evidence supports a link between sleep disorders, disturbed sleep, and adverse brain health, ranging from stroke to subclinical cerebrovasculardisease to cognitive outcomes, including the development of Alzheimer disease and Alzheimer disease–related dementias. Stroke, Ahead of Print.
New research published in the Journal of Stroke and CerebrovascularDiseases confirms that strokes thought to happen in older adults are possible in the younger (defined as 18–50 years old) population.
Stroke, Volume 56, Issue Suppl_1 , Page ADP15-ADP15, February 1, 2025. Background:White matter hyperintensities (WMH) of presumed vascular origin can be associated with vascular cognitive impairment and dementia. However, WMH are also seen in asymptomatic subjects.
We divided this population into 3 groups: (a) those with a diagnosis of CAA, (b) those with other cerebrovasculardisease without CAA, and (c) those without CAA or other cerebrovasculardisease. million hospitalized patients, 2,335 had CAA and 600,646 had other cerebrovasculardisease. years (IQR, 1.0-3.9),
Hypertension is a significant risk factor for cardiovascular and cerebrovasculardiseases and has become a global public health concern. Although hypertension results from a combination of factors, the specific mechanism is still unclear.
Multiple studies have shown that long non-coding RNAs (lncRNAs) play a significant role in the progression of cardiovascular and cerebrovasculardiseases. Multiple studies have shown that long non-coding RNAs (lncRNAs) play a significant role in the progression of cardiovascular and cerebrovasculardiseases.
Introduction of the antiamyloid immunotherapies into practice is therefore likely to present a new set of questions for clinicians treating patients with cerebrovasculardisease: Which manifestations of cerebrovasculardisease should preclude, or permit, antibody treatment?
However, the data on neurological outcomes including cerebrovasculardisease (CVA) and dementia remain a controversy. Catheter ablation (CA) of atrial fibrillation (AF) has been proved to benefit patient with symptomatic AF and heart failure.
Thrombosis continues to pose a significant challenge in cardiovascular and cerebrovasculardiseases, contributing to severe health complications such as myocardial infarction, acute ischemic stroke, and venous thromboembolism. In this paper, we comment the findings reported by Liu et al.
Results Brandenburg patients with cardiovascular diseases showed higher Lp(a) levels than healthy controls (24.2% vs. 14.8%, p = 0.001), and the high-Lp(a) group demonstrated a higher prevalence of coronary artery disease, peripheral artery disease, or cerebrovasculardisease than the low-Lp(a) group ( p = 0.004).
Methods This narrative review examines the contemporary literature assessing intermediate- and long-term event rates in patients with established CV disease treated with statins. Recurrent stroke occurs in up to 19% of patients seven years after a first cerebrovascular event.
The data were presented yesterday at the 2024 International Stroke Conference (AZ), a premier event featuring global thought leaders and dedicated to the latest in the science and treatment of cerebrovasculardisease and brain health. A total of 17 sites and 123 patients participated across the United States and France.
By comparing myocardial injury patients with non-myocardial injury patients, notable differences were observed in age, pre-existing medical conditions (e.g.,
ICD10 Codes I60-I69 were used to indicate cerebrovasculardisease. CTA Head, CTP, MRI Brain, and Non-contrast CT Head imaging use was determined from Common Procedural Terminology (CPT) codes. Detailed diagnosis and hospital demographic data to be presented.
We reviewed the literature on cerebrovascular complications in adult patients with bacterial meningitis. Cerebrovascular complications occur in one fourth of patients with bacterial meningitis. Streptococcus pneumoniaeandStaphylococcus aureusare the primary causative pathogens leading to these complications.
To this end, we developed a multi-tiered weak labeling algorithm to label a large sample of stroke alerts as being associated with cerebrovasculardisease or stroke mimics, based on diagnostic codes and selected neuroradiology reports.Methods:Using an unlabeled, previously un-analyzed institutional stroke alert registry, we developed a 4-tiered weak (..)
BP, a heritable quantitative trait affected by numerous biological and environmental stimuli, is a major cause of morbidity and mortality worldwide and is considered to be a primary modifiable factor in renal, cardiovascular, and cerebrovasculardiseases.
Introduction:Lipoprotein(a) [Lp(a)] is a known risk factor for cardiovascular disease; however, its association with cerebrovasculardisease is not as well established.Methods:Data from HCHS/SOL, a population-based cohort of Hispanics/Latinos, was utilized.
Hypertension is the primary modifiable risk factor for cardiovascular, renal, and cerebrovasculardiseases and is considered the main contributing factor to morbidity and mortality worldwide. Hypertension, Ahead of Print.
Current smoker, hypertension, heart failure, previous myocardial infarction, cerebrovasculardisease, CysC, and NT-proBNP were selected as independent risk factors for AKI. The risk prediction model was evaluated using receiver operating characteristic (ROC), calibration curve, and decision curve analysis (DCA).Results220
Background and aims Epidemiology of atherosclerotic cardiovascular disease might be different in patients with polygenic hypercholesterolemia plus high levels (≥30 mg/dl) of Lp(a) (H-Lpa) than in those with polygenic hypercholesterolemia alone (H-LDL).
Atherosclerotic cardiovascular disease (ASCVD) was defined as history/presence of coronary, peripheral, or cerebrovasculardisease. We estimated MAVE rates and cumulative incidence, overall and by ASCVD. Over half (52%) of the cohort met the ASCVD criteria. in the overall cohort and 8.7 in the ASCVD subset.
Introduction:Cerebral amyloid angiopathy (CAA) is a significant cause of cerebrovasculardisease and cognitive decline in elderly patients. Stroke, Volume 56, Issue Suppl_1 , Page AWP229-AWP229, February 1, 2025.
In the future, we hope to have more AI applications validated through clinical research and hope that the clinical decision support system can be expanded to include more aspects of stroke care, including reperfusion therapy and long-term secondary prevention, rehabilitation and so on.
Additionally, mass spectrometry was employed to measure tHcy levels in both plasma and cerebrospinal fluid (CSF) samples collected from 56 patients with cerebrovasculardisease. The viability of the cells was evaluated using MTT method.
Introduction:Ischemic stroke is an acute metabolic and cerebrovasculardisease that leads to high mortality and disability rate in the world. Stroke, Volume 56, Issue Suppl_1 , Page AWP345-AWP345, February 1, 2025.
Introduction:Intracranial aneurysm (IA), a cerebrovasculardisease affecting 3-5% of US population, leads to subarachnoid hemorrage. Stroke, Volume 56, Issue Suppl_1 , Page A78-A78, February 1, 2025.
Conclusion:We report a large cohort of MAGIC usage in the treatment of pediatric cerebrovasculardisease over approximately 3 decades. Intraprocedural complications (wire perforation, contrast extravasation, etc.) occurred in 28 (1.3%) catheter uses, of which 5 (0.2%) were catheter-related (retention/rupture).Conclusion:We
Background:Cerebral amyloid angiopathy (CAA) is a hemorrhagic cerebrovasculardisease that is thought to be due to excess protein deposition in vessel walls that lead to fragility and increase the risk of rupture. Stroke, Volume 56, Issue Suppl_1 , Page ADP1-ADP1, February 1, 2025.
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