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Prospective Multicenter International Registry of Ultrasound-Facilitated Catheter-Directed Thrombolysis in Intermediate-High and High-Risk Pulmonary Embolism (KNOCOUT PE)

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations.

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Single Bolus r-SAK Before Primary PCI for ST-Segment–Elevation Myocardial Infarction

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:It is uncertain whether adjunctive thrombolysis is beneficial for patients with ST-segment–elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) within 120 minutes of presentation. years; 14% female). years; 14% female).

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Clinical Outcomes and Predictors of Advanced Therapy for the Management of Right Heart Thrombus

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. Background:The role of advanced therapies (systemic thrombolysis, catheter-based treatment, and surgical thrombectomy) for the management of right heart thrombus is poorly defined. Younger age (odds ratio, 0.98 [95% CI, 0.96–0.99])

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Impact of Time to Catheter-Based Therapy on Outcomes in Acute Pulmonary Embolism

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Volume 18, Issue 1 , Page e014499, January 1, 2025. years; 44% women; 29% catheter-directed thrombolysis; 68% mechanical thrombectomy; and 3% both). The median time to intervention was 6.1 hours in the early group and 20.8 hours in the delayed group (P<0.001).

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A Tough ECG, But Learn From It!

Dr. Smith's ECG Blog

Marti D et al. Incidence Incidence, angiographic features and outcomes of patients presenting with subtle ST-elevation myocardial infarction.

STEMI 52
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Right precordial ST depression in a patient with chest pain

Dr. Smith's ECG Blog

Matetzky S, Freimark D, Chouraqui P, et al. Significance of ST segment elevations in posterior chest leads (V7-V9) in patients with acute inferior myocardial infarction: application for thrombolytic therapy.