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Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns.
milla1cf Tue, 06/04/2024 - 20:54 June 4, 2024 — HeartFlow, a leader in cardiovascular healthcare technology, is pleased to announce a key Medicare policy development, which should allow for future expanded patient access to their Plaque Analysis product.
Exercise prevents and reverses cardiovasculardisease, but whether high-intensity exercise training (HIIT) is safe and effective for adults after minimally invasive heart surgery is unknown. Exercise is a wonder drug for cardiovasculardisease (CVD) prevention and reversal.
The findings support that metals in the body are associated with the progression of plaque buildup in the arteries and potentially provide a new strategy for managing and preventing atherosclerosis.
(MedPage Today) -- It was common for tiny plastic particles from the environment to infiltrate people's vascular lesions, foreshadowing future cardiovasculardisease in patients who underwent carotid endarterectomy, an observational study showed.
Researchers have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack.
Inflammation of the arteries is a primary precursor and driver of cardiovasculardisease -- the No. This inflammation is associated with the buildup of dangerous plaque inside the arteries. 1 killer of people in the United States. Advanced treatments are needed to target this inflammation in patients.
However, for people with risks for heart disease, these warning signals can have a negative consequence: they can increase the size of plaque in arteries, making them narrow, and trigger inflammatory events that can cause plaque to rupture. This can set the stage for a heart attack or stroke.
More than 70% of American Indian young adults aged 20-39 and 50% of American Indian teens have cholesterol levels or elevated fat in the blood that put them at risk for cardiovasculardisease, a new study suggests.
BackgroundThe utility of screening for the degree of common carotid artery (CCA) stenosis as a predictor of cardiovasculardisease (CVD) in a general population remains unclear.Methods and ResultsWe studied 4775 Japanese men and women whose CCA was measured using bilateral carotid ultrasonography at baseline (April 1994–August 2001).
Patients with chronic inflammatory disorders such as psoriasis have an increased risk of cardiovasculardisease and elevated levels of LL37, a cathelicidin host defense peptide that has both antimicrobial and proinflammatory properties.
Background Inflammation plays a pivotal role in atherogenesis and is a causal risk factor for atherosclerotic cardiovasculardisease. Non-invasive coronary CT angiography (CCTA) enables evaluation of coronary plaque phenotype. Baseline total plaque volume was 1394 (1036, 1993) mm 3. Results The mean±SD age was 65.4±8.4
Nature Reviews Cardiology, Published online: 04 April 2024; doi:10.1038/s41569-024-01009-x In this Review, van Leent and colleagues provide an overview of current PET imaging approaches for assessment of atherosclerotic cardiovasculardisease, as well as of whole-body PET applications; discuss the link between imaging readouts and atherosclerotic plaque (..)
Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide. The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors.
In this substudy of the phase 3 Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), a team led by investigators at Massachusetts General Hospital (MGH) discovered that pitavastatin reduces plaque buildup in the heart's coronary arteries and lowers inflammation in the blood. The findings are published in JAMA Cardiology.
tim.hodson Tue, 10/01/2024 - 10:50 PHOTO CAPTION: The Elucid PlaqueIQ user interface is a fully interactive visualization of the patient’s coronary anatomy, showing specific plaque type and amount across various views to inform physician assessment of risk and patient-specific treatment pathway.
Smoking is a well-known health hazard, contributing to a wide array of diseases and conditions. Its effects on the heart are particularly alarming, as smoking significantly increases the risk of cardiovasculardiseases (CVDs) and complicates medical procedures such as minimally invasive or bloodless heart surgeries.
The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time. The answer: Risk Factors. The answer.
This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. 2022 Aug, 80 (9) 934946 Kronenberg F. J Clin Lipidol. 2024 May-Jun;18(3):e308-e319.
At present, machine learning, deep learning, and other AI technologies have been tried to be applied to intelligent diagnostic and decision making, image interpretation, accurate classification, and prognostication of cardiovasculardiseases, which has led to broad application prospects and innovation potential.
Background Although atherosclerosis (AS) can affect multiple vascular beds, previous studies have focused on the analysis of single-site AS plaques. The plaques were then categorized into culprit plaques, non-culprit plaques, and non-event plaques.
BackgroundThe level of monocyte to highdensity lipoprotein ratio (MHR) is associated with cardiovasculardiseases. Carotid plaque (CP) is an independent risk factor for cardiovasculardiseases. Journal of the American Heart Association, Ahead of Print.
Nature Reviews Cardiology, Published online: 28 January 2025; doi:10.1038/s41569-025-01124-3 Inflammation is a new therapeutic target for the prevention of cardiovasculardisease. Colchicine is a potential cheap option to target inflammation and prevent atherosclerotic plaque destabilization.
We used carotid ultrasounds to detect plaque at baseline and follow‐up in 2006 to 2009 (median follow‐up=5.5 had incident plaque (109/1104 plaque‐free participants with baseline and follow‐up ultrasounds), 11.0% Journal of the American Heart Association, Ahead of Print. Lipids were measured after a 12‐hour fast.
A decrease in the percentage of unstable core (fibro-fatty+necrotic plaque; from 14.1 [7.9–22.3] Participants underwent a coronary computed tomographic angiography at baseline and a final one at 78 weeks. The global coronary PB changed from 34.6% (32.5%–36.8%) 36.8%) at entry to 30.4% (27.4%–33.4%) 33.4%) at follow-up, which is −4.6% (−7.7%
Is coronary artery calcium (CAC) density by computed tomography (CT) inversely associated with plaque vulnerability and atherosclerotic cardiovasculardisease (ASCVD) events (coronary heart disease [CHD] and stroke)?
I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." fold higher risk for cardiac mortality and 5.5-fold
This is because the test is widely available, fast, highly reproducible, low radiation, directly reflective of total coronary plaque burden, and highly predictive of future atherosclerotic cardiovasculardisease (ASCVD) events.
The breakthrough designation, according to the Milpitas, CA-based technology company, is for an indication to improve coronary luminal diameter, restore hemodynamic modulation, and reduce plaque progression in patients with symptomatic ischemic heart disease due to discrete de novo native coronary artery lesions. of the U.S.
Atherosclerosis is characterized by a narrowing of arterial walls and can increase risk of coronary artery disease, stroke, peripheral artery disease, or kidney disorders.
Ischemic cardiovasculardisease (IHD) continues to be a significant public health problem in the U.S. Typically, ischemia is associated with epicardial coronary artery obstruction caused by atherosclerotic plaque.
The Wnt signaling pathway is thought to play an active role in the pathogenesis of several cardiovasculardiseases; however, a better understanding of this system in atherosclerosis is yet to be unraveled.
MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. Thus, intracoronary imaging modalities are crucial in this setting. From Gue at al.
BackgroundThe association between education and atherosclerotic cardiovasculardisease (ASCVD) has been well described for decades. Nevertheless, most cardiovascular risk models, including SCORE2, still do not take educational status into account even if this factor is easily assessed and costs nothing to acquire.
Exercise in a regular pattern is one of the important life style modifications which everyone can adopt to prevent or delay cardiovasculardisease. Exercise helps in various ways for prevention of cardiovasculardisease. Higher HDL levels decrease the risk of cardiovasculardisease.
According to the study, eating one to three eggs each week reduces cardiovasculardisease risk by 60%. In fact, the study discovered that people who consume four to seven eggs a week have a 75% decreased risk of acquiring cardiovasculardisease. Early cardiovasculardisease may hasten middle-aged cognitive deterioration!
Atherosclerosis is a chronic inflammatory disease characterized by endothelial dysfunction and plaque formation. Dan-Shen-Yin (DSY), a traditional Chinese herbal formula, is commonly used for cardiovasculardiseases, but its molecular mechanisms remain elusive.
Atherosclerotic cardiovasculardisease is a major health concern worldwide and requires effective preventive measures. Lp(a) (lipoprotein [a]) has recently garnered attention as an independent risk factor for astherosclerotic cardiovasculardisease, with proinflammatory and prothrombotic mechanisms contributing to its atherogenicity.
Large-scale observational data have demonstrated a robust, independent association of elevated lipoprotein(a) (Lp[a]) levels with atherosclerotic cardiovasculardisease (CVD), stroke, and peripheral artery disease.
As with elevated LDL-cholesterol, high levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heart attacks and strokes. Triglycerides store unused calories and provide energy to the body. and Canada.
Background:The role of immune suppressive microenvironment, promulgated by the presence of Myeloid Derived Suppressor Cells (MDSC) have been the major focus of research delineating the underlying mechanisms of cardiovasculardiseases (CVD). 3ng/day for 15 days).M-MDSCs
26th August 2022 And so, after a great deal of faffing about, my article on cardiovasculardisease ‘Assessing cardiovasculardisease: looking beyond cholesterol’ has been made free to view. Eric Westman is a staunch ally in the crusade to look at different causal models of cardiovasculardisease.
High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heart attacks and strokes. An estimated 1 in 5 U.S. Patients’ average triglyceride level at baseline was about 900 mg/dL.
Immune-mediated inflammatory diseases (IMIDs) are recognised risk factors for accelerated atherosclerotic cardiovasculardisease (CVD), particularly in younger individuals and women who lack traditional CVD risk factors.
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