Circulation

DECEMBER 7, 2023

Resistance training not only can improve or maintain muscle mass and strength, but also has favorable physiological and clinical effects on cardiovascular disease and risk factors. We also address the utility of resistance training for promoting cardiovascular health in varied healthy and clinical populations.

Cardiovascular Disease 85

Cardiovascular Disease Exercise Risk Factors Physiology 85

Frontiers in Cardiovascular Medicine

MARCH 11, 2025

IntroductionHeat therapy (HT), particularly in the form of whole-body sauna bathing, has emerged as a promising intervention for the management of cardiovascular disease (CVD). Such responses closely parallel the physiological adaptations observed during aerobic exercise.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Exercise Physiology Cardiovascular Disease 52

Physiologically Speaking

OCTOBER 11, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. When we don’t get enough sleep, our physiology suffers—insulin sensitivity tanks, cognitive function wanes, and physical performance is drastically impaired. I know I have (new dad here). and woke up at 7 a.m. (8

Blood Pressure 90

Blood Pressure Exercise Physiology Cardiovascular Disease 90

Frontiers in Cardiovascular Medicine

MARCH 10, 2024

Based on the ability of modulating the levels of these PIPs, MTMRs exert physiological functions such as vesicle trafficking, cell proliferation, differentiation, necrosis, cytoskeleton, and cell migration. This review summarizes the functions of MTMRs and highlights their pathophysiological roles in cardiovascular diseases.

Cardiovascular Disease 64

Cardiovascular Disease Aneurysm Physiology Aortic 64

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

The physiology of lipid droplets (LDs) has been most extensively characterized in adipocytes, but LDs also accumulate in endothelial cells lining blood vessels in response to changing levels of triglycerides.

Cardiovascular Disease 93

Cardiovascular Disease Atherosclerosis Physiology Hypertension 93

Frontiers in Cardiovascular Medicine

JULY 10, 2024

Uromodulin, also referred to as Tamm Horsfall protein (THP), is a renal protein exclusively synthesized by the kidneys and represents the predominant urinary protein under normal physiological conditions.

Cardiovascular Disease 52

Cardiovascular Disease Physiology Biomarkers 52

Frontiers in Cardiovascular Medicine

MAY 26, 2024

In addition to the receptor, it also participates in complex pathological and physiological processes, including regulating the RAS system, apelin, KKS system, and immune system. In addition to affecting the respiratory system, viral infections also interact with cardiovascular diseases.

COVID-19 106

COVID-19 Research Cardiovascular Disease Physiology 106

Frontiers in Cardiovascular Medicine

JUNE 3, 2024

The kynurenine pathway (KP) serves as the primary route for tryptophan metabolism in most mammalian organisms, with its downstream metabolites actively involved in various physiological and pathological processes.

Cardiovascular Disease 52

Cardiovascular Disease Atherosclerosis Myocardial Infarction Physiology 52

Open Heart

MAY 27, 2024

Background Pre-existing cardiovascular disease (CVD) or cardiovascular risk factors have been associated with an increased risk of complications following hospitalisation with COVID-19, but their impact on the rate of recovery following discharge is not known. Results From a total population of 2545 patients (38.8%

COVID-19 52

COVID-19 Cardiovascular Disease Risk Factors Physiology 52

Frontiers in Cardiovascular Medicine

MARCH 25, 2025

ObjectivesNoise pollution has become an increasingly severe environmental issue in modern society and has been recognized for its adverse effects on cardiovascular diseases. Hypertension induced by noise exposure has garnered significant research interest and a large quantity of studies have been conducted.

Hypertension 52

Hypertension Public Health Research Physiology 52

Physiologically Speaking

JULY 24, 2024

Part I: 10-Years longitudinal data on KETOGENIC DIET and Safety, Efficacy & Advanced Cardiovascular Physiology in a patient with HIGH RISK cardiovascular disease (Type 1 Diabetes)?

Diabetes 115

Diabetes Diet Physiology Biomarkers 115

Nature Reviews - Cardiology

MARCH 4, 2025

Nature Reviews Cardiology, Published online: 05 March 2025; doi:10.1038/s41569-025-01141-2 In this Review, Xiao and Sluijter describe the role of extracellular vesicles in cardiovascular physiology and pathology, and highlight their potential diagnostic and therapeutic utility for cardiovascular disease.

Physiology 75

Physiology Cardiovascular Disease 75

Physiologically Speaking

JULY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Dozens if not hundreds of (albeit observational) studies have linked a short sleep duration to a number of health conditions including type 2 diabetes and cardiovascular disease. on Tuesday, and 7 on Wednesday.

Chronic Disease 64

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 64

Physiologically Speaking

JANUARY 10, 2024

Our body’s physiological processes oscillate on a 24-hour cycle known as the circadian rhythm. Circadian rhythms in blood pressure and heart rate, among other functions, are crucial for cardiovascular health and preventing cardiovascular disease. How could ALAN and the SCN affect cardiovascular health?

Blood Pressure 131

Blood Pressure Physiology Cardiovascular Disease Obesity 131

Hypertension Journal

JULY 14, 2023

The angiotensin-II type 1 receptor is an important G protein-coupled receptor involved in the regulation of cardiovascular function and has been implicated in the progression of cardiovascular diseases.

Cardiovascular Disease 40

Cardiovascular Disease Atherosclerosis Physiology Hypertension 40

Journal of Cardiovascular Pharmacology

JULY 18, 2012

Abstract: The renin angiotensin aldosterone system (RAAS) is a paramount target for the pharmacological treatment of cardiovascular diseases. Next, a physiology-based PK model for enalapril and enalaprilat was developed and coupled to the RAAS model. For all drugs, the error numerics were acceptable.

Physiology 40

Physiology Biomarkers Pharmacology Cardiovascular Disease 40

Frontiers in Cardiovascular Medicine

JULY 2, 2024

Cardiovascular diseases account for a significant portion of the worldwide mortality rate. This aroused interest among the specialised scientific community, seeking for solutions based on non-clinical and clinical investigations, to shed light onto the physio-pathology of cardiovascular impairment.

Atherosclerosis 52

Atherosclerosis Cardiovascular Disease Physiology Biomarkers 52

Physiologically Speaking

JANUARY 29, 2024

Joseph Watso, PhD, is an Assistant Professor in the Department of Nutrition & Integrative Physiology at Florida State University. Joe directs the Cardiovascular & Applied Physiology (CAP) Laboratory which has the mission to advance knowledge on cardiovascular disease prevention and treatment strategies.

Physiology 59

Physiology Laboratory Cardiovascular Disease Research 59

DAIC

JULY 29, 2024

Early identification allows for timely initiation of guideline-directed medical therapy for secondary prevention of cardiovascular disease, cerebrovascular disease, and limb events. The VasoGuard V-Series signifies a significant step forward for physiologic testing in international standards compliance.

Certification 111

Certification Peripheral Arterial Disease Cerebrovascular Disease Quality of Life 111

Physiologically Speaking

JUNE 7, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Lastly, insufficient sleep is also a massive health liability, leading to cardiovascular disease, diabetes, and cognitive decline. To receive new posts and support my work, consider becoming a free or paid subscriber.

Exercise 52

Exercise Physiology Blood Pressure Outcomes 52

Physiologically Speaking

MARCH 8, 2024

Welcome to the Physiology Friday newsletter. On Wednesday, I published a post on the philosophy and physiology of an “exercise pill.” Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Acute sleep loss is also insidious.

Physiology 52

Physiology Exercise Diet Research 52

Physiologically Speaking

JANUARY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. COSMOS tested a cocoa extract supplement and a multivitamin-mineral supplement against one another and a placebo for reducing the risk of cardiovascular disease and cancer.

Physiology 52

Physiology Diet Cardiovascular Disease BMI 52

Circulation

NOVEMBER 29, 2023

BACKGROUND:Cholesterol efflux capacity (CEC) predicts cardiovascular disease independently of high-density lipoprotein (HDL) cholesterol levels. Enhanced CEC, as seen with the smaller particles, predicts decreased cardiovascular disease risk. Circulation, Ahead of Print.

Cholesterol 75

Cholesterol Cardiovascular Disease Physiology Circulation 75

Hypertension Journal

SEPTEMBER 6, 2023

Excess dietary salt (NaCl) intake is strongly correlated with cardiovascular disease and is a major contributing factor to the pathogenesis of hypertension. Hypertension, Ahead of Print.

Physiology 40

Physiology Blood Pressure Hypertension Cardiovascular Disease 40

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Meanwhile, the risk of suffering from cardiovascular disease (CVD) has been increasing with ageing. Cancer, atrial fibrillation (AF) and coronary artery disease share some common factors and interact with each other, such as obesity, aging, diabetes, and inflammation, but the potential specific mechanism is still unclear.

Atrial Fibrillation 64

Atrial Fibrillation Cancer Embolism Coronary Artery Disease 64

DAIC

FEBRUARY 28, 2024

The new scientific statement, “Use of Artificial Intelligence in Improving Outcomes in Heart Disease,” comes amid intense attention on AI as a way to improve cardiovascular disease prevention, detection, diagnosis and treatment.

Best Practices 111

Best Practices Technology Cardiovascular Disease Strokes 111

Frontiers in Cardiovascular Medicine

MAY 15, 2024

Since the discovery of the non-neuronal cardiac cholinergic system (NNCCS), several studies have provided evidence for the positive role of acetylcholine (ACh) released from cardiomyocytes against cardiovascular diseases, such as sympathetic hyperreactivity-induced cardiac remodeling and dysfunction as well as myocardial infarction.

Myocardial Infarction 52

Myocardial Infarction Physiology Cardiovascular Disease 52

Heart BMJ

MAY 10, 2024

While progress has been made in the management of most aspects of cardiovascular disease, the incidence and prevalence of heart failure (HF) remains high. In this article, we will review the physiology of NPs and study their biological effects. We will also explore the role of NPs as a potential therapeutic agent.

Biomarkers 52

Biomarkers Heart Failure Physiology Article 52

Journal of Cardiovascular Pharmacology

OCTOBER 14, 2024

As a result, they serve as key targets for therapeutic interventions in cardiovascular diseases. As a result, they serve as key targets for therapeutic interventions in cardiovascular diseases. The objective of this article is to focus on the role that TRPC channels play in the cardiovascular system.

Cardiovascular Disease 40

Cardiovascular Disease Cardiac Function Article Physiology 40

Hypertension Journal

DECEMBER 7, 2023

ET (endothelin) is a powerful vasoconstrictor 21-amino acid peptide present in many tissues, which exerts many physiological functions across the body and participates as a mediator in many pathological conditions. Hypertension, Ahead of Print.

Kidney Disease 45

Kidney Disease Hypertension Pulmonary Atherosclerosis 45

Cardiomatics

APRIL 5, 2024

Prolonged ambulatory ECG monitoring, commonly referred to as Holter testing, increases the chance of detecting abnormalities responsible for the symptoms of cardiovascular diseases, especially those whose pathognomonic symptoms occur only periodically. The left bundle and right bundle terminate in the Purkinje fibers.

Arrhythmia 92

Arrhythmia Tachycardia Bradycardia Electrocardiogram 92

Journal of the American Heart Association

APRIL 10, 2025

BackgroundExercise parameters can be altered in children with congenital heart disease or acquired heart disease compared with children with normal hearts. Exercise testing has proven a useful tool to predict patient outcomes and even the need for reintervention in several cardiovascular disease processes.

Exercise 40

Exercise Congenital Heart Disease Congenital Heart Disease 40

Physiologically Speaking

APRIL 3, 2024

Physiologically Speaking is a reader-supported publication. Some research suggests that having a consistent sleep duration (sleeping a similar number of hours each night) and sleep timing (going to bed and waking up around the same time each day) lowers your risk for cardiovascular disease. Do I expect you to adopt these rules?

Exercise 103

Exercise Physiology Research Cardiovascular Disease 103

Wellnest

JANUARY 23, 2024

Chirag Doshi’s take on the increasing Cardiac Emergencies in Gujarat Dr. Chirag Doshi, the director of the UN Mehta Institute of Cardiology and Research Centre (UNMICRC), has highlighted the increasing global incidence of cardiovascular diseases, attributing it to lifestyle choices and various risk factors.

COVID-19 52

COVID-19 Cardiovascular Disease Risk Factors Blood Pressure 52

Wellnest

JUNE 26, 2023

Using this data; the AI can further predict the patient’s cardiovascular disease risk using optic disks and blood vessels. Alun Hughes, professor of Cardiovascular Physiology and Pharmacology at London’s UCL, said Google’s approach sounded credible because of the “long history of looking at the retina to predict cardiovascular risk.”

Cardiovascular Disease 52

Cardiovascular Disease Blood Pressure Patient Care Pharmacology 52

Circulation

NOVEMBER 11, 2024

Background:Ischemic heart disease (IHD) is a prevalent cardiovascular disease (CVD) associated with high morbidity and mortality. Frailty and CVD are often interrelated, affecting disease and treatment outcomes. Over 600,000 percutaneous coronary interventions (PCI) are performed each year for IHD.

Heart Disease 40

Heart Disease Hospital Inpatient Outcomes 40

Circulation

NOVEMBER 11, 2024

Introduction:During natural aging, physiological remodeling of the heart is a critical for the cardiovascular disease and heart failure. miR-30a-5p is related to kidney injury, cancer, and autoimmune diseases. Circulation, Volume 150, Issue Suppl_1 , Page A4139176-A4139176, November 12, 2024.

Physiology 40

Physiology Cancer Heart Failure Cardiovascular Disease 40