This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovasculardisease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.
Atherosclerosisa key driver of cardiovasculardisease (CVD)continues to be a significant global health issue. This imbalance is partly due to limited healthcare access, fewer preventive resources, and challenges in addressing riskfactors such as obesity and diabetes.
Other studies have also unearthed more intricate connections which suggests that physiological conditions, underpinned by biological and chemical factors, may also play a pivotal role in influencing cardiovasculardisease (CVD). In 2021 alone, CVD accounted for over 900,000 deaths in the U.S. and approximately 19.91
Atherosclerotic cardiovasculardisease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
Background and aims In the non-metropolitan region of Brandenburg (Germany), which is characterized by high rates of cardiovasculardiseases and underserved medical care, there is a lack of awareness regarding lipoprotein(a) [Lp(a)] as a riskfactor. vs. 53.2%, p = 0.014) and myocardialinfarction (24.7%
Multivariable logistic regression models were used to estimate BMIstratified associations between SMuRFless status and outcomes.ResultsThe study included 44 538 patients with firstpresentation acute myocardialinfarction, of whom 4454 were SMuRFless. Journal of the American Heart Association, Ahead of Print.
Owing to improved management, the life expectancy of patients with hemophilia has increased significantly and predisposes them to risk of cardiovasculardiseases and thrombotic events. The primary outcome was to estimate the prevalence of cardiovascularriskfactors in patients with hemophilia compared to the general population.
Background and objectives Hypertension is one of the most serious riskfactors and the leading cause of mortality in patients with cardiovasculardiseases (CVDs). It is necessary to accurately predict the mortality of patients suffering from CVDs with hypertension. Methods The synopsis of our research is as follows.
BackgroundRecent evidence highlights an increasing incidence of myocardialinfarction in young women. years]) admitted to the China Chest Pain Center Database between 2016 and 2021.
The Minneapolis Heart Institute Foundation (MHIF) is presenting leading research focused on trends in ST-elevation myocardialinfarction (STEMI), the most severe form of a heart attack, at the American College of Cardiology’s Annual Scientific Session (ACC.24), 24), being held April 6-8 in Atltanta, GA.
BackgroundMyocardial infarction is a cardiovasculardisease that significantly contributes to global morbidity and disability. Univariate Mendelian analyses revealed genetic associations among 9 categories of dietary habits (83 types) and myocardialinfarction.
Objective Observational studies show that hypertensive disorders of pregnancy (HDPs) are related to unfavourable maternal cardiovasculardisease (CVD) risk profiles later in life. In our primary analysis, we applied Mendelian randomisation using inverse-variance weighted regression analysis in ever pregnant women.
The primary endpoint was composite (cardiovascular death, myocardialinfarction, stroke), and the secondary endpoints were myocardialinfarction and stroke. The composite endpoint was 159 cases, myocardialinfarction in 27 cases and cerebral infarction in 72 cases.
Primordial prevention is changing the environment around you so you do not develop the riskfactors for heart disease and, by extension, do not get the disease early in life. Blood Pressure Control High blood pressure is the riskfactor associated with the greatest number of deaths worldwide. N Engl J Med.
We assessed the association of cannabis use (number of days of cannabis use in the past 30 days) with self‐reported cardiovascular outcomes (coronary heart disease, myocardialinfarction, stroke, and a composite measure of all 3) in multivariable regression models, adjusting for tobacco use and other characteristics in adults 18 to 74 years old.
The lead investigators for the study are Dr. Carlo De Cecco (Emory University, Atlanta) and Dr. Kolossváry added, “The PRE-VUE registry will empower us to see the true additive value of CT-derived, histologically validated plaque volumes in predicting future adverse cardiovascular events.” 2017 23, April 2020; Available from: [link].
BackgroundEffective therapies for reducing cardiovasculardisease (CVD) risk in people with elevated lipoprotein(a) are lacking, especially for primary prevention. Due to potential confounding by indication, we matched aspirin users to nonusers using a propensity score based on CVD riskfactors. versus 55.3%,P=0.02),
The primary outcome was risk of an ASCVD hospitalization composite outcome (myocardialinfarction, coronary artery bypass graft, percutaneous coronary intervention, stroke, transient ischemic accident) after COPD hospitalization relative to before COPD hospitalization.
Specifically, LODOCO reduces cardiac event risk in adult patients with established atherosclerotic cardiovasculardisease (ASCVD) by an additional 31% as compared to placebo. Caristo’s CaRi-Heart technology applies advanced AI algorithms to routine cardiac CT scans to visualize and quantify coronary inflammation.
But What About Stress & Heart Disease? When stress is included in the riskfactor profile for a future heart attack, it comes in third on the list after abnormal cholesterol and smoking 1. 5 Effects of stress on the development and progression of cardiovasculardisease. Bring back the real emergencies, I say!
Introduction Atherosclerotic cardiovasculardisease (ASCVD) is one of the main causes of morbidity and mortality in developed countries and entails high resources use and costs for health systems. The resources use within two years of the diagnosis was estimated in order to estimate the average cost of patient follow-up.
Objective Lipoprotein(a) (Lp(a)) is an important genetically determined riskfactor for atherosclerotic vascular disease (ASCVD). With the development of Lp(a)-lowering therapies, this study sought to characterise patterns of Lp(a) levels in a global ASCVD population and identify racial, ethnic, regional and gender differences.
BACKGROUND:Up to 50% of women report sleep problems in midlife, and cardiovasculardisease (CVD) is the leading cause of death in women. How chronic poor sleep exposure over decades of midlife is related to CVD risk in women is poorly understood. Circulation, Ahead of Print.
Introduction:Inflammation is pivotal in initiating and accelerating atherosclerotic cardiovasculardisease (ASCVD). CIC features are associated with ASCVD endpoints and mortality even after adjustment for traditional riskfactors and laboratory values, including hs-CRP.
The primary outcome was a composite of the incidence of myocardialinfarction and ischemic and hemorrhagic stroke, obtained by tracking the medical use data of the first-ever ICD-10 codes. HTN elevated the incidence risk of major cardiovasculardisease by 2.16 years and median follow-up duration was 15.9
Introduction: Addressing the Need for Improved LDL Management in the US There is a clear need for innovative treatments to combat cardiovasculardisease (CVD). Heart disease remains the leading cause of death for men and women. However, every 40 seconds, an individual in the US suffers a heart attack.
Left ventricular (LV) global longitudinal strain (GLS) assessed via feature tracking cardiac magnetic resonance imaging is associated with increased risk of major adverse cardiovascular events (MACE). LV GLS is associated with MACE in adults without prevalent cardiovasculardisease (CVD). 2.38, p = 0.04).
Recommendation from UK National Institute for Health and Care Excellence is that people with or at high risk of cardiovasculardisease consume at least one portion of oily fish a week. The authors reported that the regular use of fish oil supplements might be a riskfactor for atrial fibrillation among general population.
This has major potential to refine risk stratification and enhance patient management. Dr. Pradeep Natarajan (United States of America) suggested that polygenic risk scores could play a larger role in identifying individuals at risk for cardiovasculardisease (CVD). Dr. Jeanine E.
Brian Bergman, MD “Treatments to reduce high triglycerides are an unmet clinical need,” said Brian Bergmark, MD , of the Thrombolysis in MyocardialInfarction (TIMI) Study Group at Brigham and Women’s Hospital and Harvard Medical School and the study’s principal investigator. and Canada.
As we get older, the risk of dementia increases for everyone, regardless of riskfactor control. Poor Sleep Is A Major RiskFactor For Insulin Resistance. Insulin resistance is a significant driver of cardiovascularrisk. Obesity is also a key driver of risk for cardiovasculardisease.
Background Sepsis is associated with an increased risk of adverse cardiovascular events in a magnitude comparable to other major cardiovascularriskfactors. We conducted a scoping review to map existing evidence and identify research gaps relating to cardiovascular dysfunction following sepsis.
The identification of a variant in theHDAC9gene as a riskfactor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease. Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023.
BackgroundThe prognostic value of triglyceride-glucose (TyG) has been well described in patients with coronary artery disease (CAD). Hyperhomocysteinemia (HHcy) promotes insulin resistance and has also been regarded as a potential riskfactor for cardiovasculardisease.
6.9), 3 with comparative studies consistently demonstrating a better prognosis than for those who experience AMI associated with obstructive coronary artery disease. See "Prevention of cardiovasculardisease events in those with established disease (secondary prevention) or at very high risk".) Lindahl et al.
Objective American Indians and Alaska Natives (AI/ANs) are an understudied population at high risk for cardiovasculardiseases (CVDs); little is known about contextual factors contributing to CVDs in AI/ANs. Individual LS7 factors were summarised as ideal and poor levels. Healthcare access measures represented SDH.
More than 70% of patients with atherosclerotic cardiovasculardisease (ASCVD) are still not achieving their LDL-C target, so there remains a vast unmet need among high-risk patients for more varied and effective treatment options. Despite current treatment options, the global burden of dyslipidaemia is on the rise. JAMA Cardiol.
26th August 2022 And so, after a great deal of faffing about, my article on cardiovasculardisease ‘Assessing cardiovasculardisease: looking beyond cholesterol’ has been made free to view. Eric Westman is a staunch ally in the crusade to look at different causal models of cardiovasculardisease.
Background:The Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes (SUSTAIN-6) trial showed cardiovasculardisease (CVD) benefits of semaglutide therapy in patients with type 2 diabetes mellitus (T2DM).Purpose:To year follow-up time).Results:Among
Introduction Hypertension is the leading modifiable riskfactor for cardiovasculardisease and is implicated in half of all strokes and myocardialinfarctions.
Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovasculardisease. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a riskfactor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population.
Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major riskfactor for cardiometabolic disease. 5, 6] So, it seems that once cardiovasculardisease is present, then obesity may offer some degree of protection. to 25 kg/m2) and underweight (BMI less than 18.5
He had no apparent riskfactors for cardiovasculardisease. High-Sensitivity Cardiac Troponin Concentrations at Presentation in Patients With ST-Segment Elevation MyocardialInfarction. Pain largely resolved prior to EMS arrival but completely subsided after prehospital NTG and aspirin. Gray, A., &
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content