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A gentler approach to monitor for heart transplant rejection

Frontiers in Cardiovascular Medicine

Despite developments in circulating biomarker and imaging technology in the assessment of cardiovascular disease, the surveillance and diagnosis of heart transplant rejection has continued to rely on histopathologic interpretation of the endomyocardial biopsy.

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Two promising approaches in the treatment of myocardial infarction: stem cells and gene therapy

Frontiers in Cardiovascular Medicine

Cardiovascular diseases (CVDs), characterized by a high incidence rate and high mortality, have become the leading cause of death globally. CVDs include coronary heart disease, stroke, hypertension, and peripheral vascular diseases. In China, the death rate of CVDs ranks the first in all major diseases.

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Using Stem Cell-derived Heart Muscle Cells to Advance Heart Regenerative Therapy

DAIC

Study shows that cardiac spheroids, derived from human induced pluripotent stem cells, can be easily transported and injected into damaged areas of the heart to promote its regeneration and recovery of function. Cardiovascular diseases are still among the top causes of death worldwide, and especially prevalent in developed countries.

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Highlights of ACC 2024

Cardiology Update

Investigators assessed if empagliflozin could lower the risk of hospitalization for heart failure (HF) or death from cardiovascular disease (CVD). The primary endpoint was a composite of all-cause mortality, left ventricular assist device (LVAD)/heart transplantation, HF hospitalizations, worsening HF, and KCCQ score changes.

Angina 52
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Abstract 4139383: Non-Inferiority Of Extracorporeal Photopheresis To Immunosuppression Therapy In Heart Transplantation Rejection

Circulation

Background:Immunosuppressive (IS) therapy is currently used as first-line treatment for heart transplant (HTx) rejection. Circulation, Volume 150, Issue Suppl_1 , Page A4139383-A4139383, November 12, 2024. However, they are not without complications, and less toxic therapies are needed. years, males: 58.4%).

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Why You Probably Already Have Heart Disease But Just Don't Know It.

Dr. Paddy Barrett

The prevalence of smoking back in the 1950s would have been much higher, but even recent studies on ‘healthy’ heart transplant donors who died from events such as road traffic accidents still show high rates of very early-stage plaque buildup 4. It is a marker of where someone is on a disease progression pathway.

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Championing Change: Celebrating Cardiometabolic Health Congress (CMHC) Women Faculty

Cardiometabolic Health Congress

Anuradha Lala-Trindade, MD: She focuses on the selection and care of patients with mechanical circulatory support devices and heart transplantation, genetic cardiomyopathies, and perioperative management of high-risk cardiac surgical cases.