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Despite developments in circulating biomarker and imaging technology in the assessment of cardiovasculardisease, the surveillance and diagnosis of hearttransplant rejection has continued to rely on histopathologic interpretation of the endomyocardial biopsy.
Cardiovasculardiseases (CVDs), characterized by a high incidence rate and high mortality, have become the leading cause of death globally. CVDs include coronary heartdisease, stroke, hypertension, and peripheral vascular diseases. In China, the death rate of CVDs ranks the first in all major diseases.
Study shows that cardiac spheroids, derived from human induced pluripotent stem cells, can be easily transported and injected into damaged areas of the heart to promote its regeneration and recovery of function. Cardiovasculardiseases are still among the top causes of death worldwide, and especially prevalent in developed countries.
Investigators assessed if empagliflozin could lower the risk of hospitalization for heart failure (HF) or death from cardiovasculardisease (CVD). The primary endpoint was a composite of all-cause mortality, left ventricular assist device (LVAD)/hearttransplantation, HF hospitalizations, worsening HF, and KCCQ score changes.
Background:Immunosuppressive (IS) therapy is currently used as first-line treatment for hearttransplant (HTx) rejection. Circulation, Volume 150, Issue Suppl_1 , Page A4139383-A4139383, November 12, 2024. However, they are not without complications, and less toxic therapies are needed. years, males: 58.4%).
The prevalence of smoking back in the 1950s would have been much higher, but even recent studies on ‘healthy’ hearttransplant donors who died from events such as road traffic accidents still show high rates of very early-stage plaque buildup 4. It is a marker of where someone is on a disease progression pathway.
Anuradha Lala-Trindade, MD: She focuses on the selection and care of patients with mechanical circulatory support devices and hearttransplantation, genetic cardiomyopathies, and perioperative management of high-risk cardiac surgical cases.
Cardiovasculardisease (CVD) remains the leading cause of morbidity and mortality worldwide, with inflammation playing a pivotal role in its pathogenesis. Understanding the intricate interplay between T cells and cardiovascular pathology is essential for developing novel immunotherapeutic strategies against CVD.
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