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Study unveils impact of cardiovascular risk factors on genetic predisposition to heart disease

Medical Xpress - Cardiology

Heersink School of Medicine have unveiled critical insights into the influence of high-proportion spliced-in titin truncating variants, or hiPSI TTNtv, on cardiovascular disease risk. Physician-scientists from the University of Alabama at Birmingham Marnix E.

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Direct-to-Consumer Genetic Testing for Cardiovascular Disease: A Scientific Statement From the American Heart Association

Circulation

In many cases, direct-to-consumer genetic testing advertises information that could inform ones risk of heritable disease, including insight into having a genetic predisposition to cardiovascular disease or data about gene-drug interactions that could affect response to cardiovascular medications.

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Genetic predisposition to nephropathy and associated cardiovascular disease in people with type 1 diabetes: role of the angiotensinI-converting enzyme (ACE), and beyond; a narrative review

Cardiovascular Diabetology

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

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Effects of vitamin D signaling in cardiovascular disease: centrality of macrophage polarization

Frontiers in Cardiovascular Medicine

Among the leading causes of natural death are cardiovascular diseases, cancer, and respiratory diseases. Factors causing illness include genetic predisposition, aging, stress, chronic inflammation, environmental factors, declining autophagy, and endocrine abnormalities including insufficient vitamin D levels.

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Gestational Diabetes and Future CVD

American College of Cardiology

What is the causality between genetic predisposition to gestational diabetes mellitus (GDM) and the risk of cardiovascular disease (CVD)?

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Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease

Frontiers in Cardiovascular Medicine

However, the influence of ICP on cardiovascular disease (CVD), including hypertension (HTN) and coronary artery disease (CAD), has not been thoroughly investigated.MethodsThis study explores the causal relationship between ICP and CVD (HTN, CAD) using Mendelian Randomization (MR). 4% of pregnancies.

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Role of LDL-C in ASCVD

HCPLive

Panelists discuss how elevated LDL-C levels significantly contribute to ASCVD development through both modifiable lifestyle factors and genetic predisposition, making it a critical target for cardiovascular disease prevention.