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There are several factors which increase the risk of cardiovasculardisease in survivors of spinal cord injury. Higher risk of myocardialinfarction, heart failure and atrial fibrillation was noted in spinal cord injury survivors compared to controls. Survivors with severe disability had the highest risk. PMID: 17251696.
Exercise in a regular pattern is one of the important life style modifications which everyone can adopt to prevent or delay cardiovasculardisease. Exercise helps in various ways for prevention of cardiovasculardisease. Maintaining normal blood pressure also reduces the risk of stroke and myocardialinfarction.
General information is that fish oil supplements are beneficial for cardiovascular health. Recommendation from UK National Institute for Health and Care Excellence is that people with or at high risk of cardiovasculardisease consume at least one portion of oily fish a week.
CLEAR trial was a double blind, randomized, placebo controlled trial of patients who were unable or unwilling to take statins due to unacceptable adverse effects and had or were at high risk for cardiovasculardisease. CLEAR trial had patients for both primary and secondary prevention of cardiovasculardisease.
EMPACT-MI 1 ( NCT04509674 ) studied the effects of empagliflozin in patients who have experienced myocardialinfarction (MI). Investigators assessed if empagliflozin could lower the risk of hospitalization for heart failure (HF) or death from cardiovasculardisease (CVD). of patients in the PCI group compared to 3.4%
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