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MicroRNA-1 Deficiency Is a Primary Etiological Factor Disrupting Cardiac Contractility and Electrophysiological Homeostasis

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Dysregulation of miR1 has been associated with various heart diseases, where a significant reduction (>75%) in miR1 expression has been observed in patient hearts with atrial fibrillation or acute myocardial infarction.

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Bridging the Gap: AI-Powered Rhythm Monitoring in Sub-Saharan Africa

Cardiomatics

Cardiovascular diseases, including arrhythmias, are a growing health concern in sub-Saharan Africa. A recent study in JACC: Clinical Electrophysiology highlights this issue and explores AI-powered solutions. Repurposing common research devices can also support electrophysiological studies in resource-limited settings.

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Biosense Webster Begins Enrollment of Pivotal Trial Evaluating the Laminar Left Atrial Appendage Elimination Device?

DAIC

The first procedures, performed by leading physicians Saibal Kar , MD, FACC, FSCAI, (Program Director, Cardiovascular Disease Fellowship, Los Robles Health System , California, HCA Healthcare National Physician Director, Interventional Cardiology) and Devi Nair , MD, FACC, FHRS, (Director, Cardiac Electrophysiology Division, St.

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Blocking interleukin-6 trans-signaling in AF: Promises and challenges

HeartRhythm

Atrial fibrillation (AF) stands as the most prevalent cardiovascular disease, posing significant risks of stroke, heart failure (HF), and other complications that contribute to morbidity and mortality.

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American College of Cardiology ACC.24 Late-breaking Science and Guidelines Session Summary

DAIC

Session 104) - What Is Really New in Electrophysiology That Will Change My Practice? The Guidelines Sessions at ACC.24 24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m.

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Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation

Circulation

BACKGROUND:Clonal hematopoiesis of indeterminate potential (CHIP), a common age-associated phenomenon, associates with increased risk of both hematological malignancy and cardiovascular disease. Mice underwent in vivo invasive electrophysiology studies and ex vivo optical mapping.

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Validation of a Demography-Based Adaptive QT Correction Formula Using Pediatric and Adult Datasets Acquired From Humans and Guinea Pigs

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:QT correction (QTc) formulae are widely used in clinical and research settings but often underperform, possibly due to demographic influences on the QTheart rate (HR) relationship.