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(MedPage Today) -- The FDA approved semaglutide (Ozempic) to reduce the risk of kidneydisease worsening, kidney failure, and death due to cardiovasculardisease in adults with type 2 diabetes and chronic kidneydisease (CKD), making it the only.
Diabetickidneydisease (DKD) is associated with a higher risk of cardiovasculardisease (CVD). Pentoxifylline (PTF), a nonselective phosphodiesterase inhibitor with anti-inflammatory, antiproliferative, and a.
Diabetes affects millions of Americans. If managed well through proper diet and medication, those with diabetes can lead full and active lives. There are however some serious complications commonly associated with diabetes, like cardiovasculardisease, kidneydisease, and PAD (Peripheral Artery Disease).
Evidence from the Look AHEAD study suggests achieving remission in type 2 diabetes is associated with risk reductions in chronic kidneydisease and cardiovasculardisease.
Among participants with type 2 diabetes and cardiovasculardisease, chronic kidneydisease, or both, oral semaglutide (14 mg) was associated with a lower risk of cardiovascular events than placebo after 4 years of follow-up.
2 Most are balancing multiple comorbidities, such as obesity, diabetes, hypertension and chronic kidneydisease (CKD). A Trial to Learn How Well Finerenone Works and How Safe it is in Adult Participants With Non-diabetic Chronic KidneyDisease (FIND-CKD). Diabetes Care. 4 Approximately 6.7
A new JAMA study revealed that a shocking 90% of US adults are at risk of developing cardiovascular-kidney-metabolic (CKM) syndrome, underscoring the need for preventative action before we face a wave of CKM-related heart disease. Stage 4 (heart disease, with or without kidneydisease) – 9.2%
Atherosclerotic cardiovasculardisease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
BackgroundThe relationship between resting heart rate (RHR) and the risk of end‐stage renal disease (ESRD) among those without cardiovasculardisease remains unclear. These results suggest that RHR may serve as a risk factor for kidneydisease in individuals without established cardiovasculardisease risk factors.
The goal of the phase 3b SOUL trial was to assess the cardiovascular efficacy of oral semaglutide, a GLP-1 receptor agonist, and to determine the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovasculardisease (ASCVD), chronic kidneydisease (CKD), or both.
ETs were shown to play important roles among others, in systemic hypertension, particularly when resistant or difficult to control, and in pulmonary hypertension, atherosclerosis, cardiac hypertrophy, subarachnoid hemorrhage, chronic kidneydisease, diabeticcardiovasculardisease, scleroderma, some cancers, etc.
Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidneydisease, or heart failure, as well as among adults with few cardiovascular risk factors.
What is the value of the new American Heart Association’s (AHA’s) PREVENT equation(s) for primary prevention that use routinely available clinical variables including obesity, diabetes, kidneydisease, and social risk for predicting 10- and 30-year absolute risk of cardiovasculardisease (CVD) including each atherosclerotic CVD (ASCVD) and heart (..)
It’s well known that heart disease is the U.S.’s s top cause of death, and our rising CVD rates have been widely covered, but a look back on some of the biggest stories of 2024 suggests that cardiovasculardisease is about to become a much bigger problem. A JAMA analysis of 11k adults revealed that only 10.6%
Owing to improved management, the life expectancy of patients with hemophilia has increased significantly and predisposes them to risk of cardiovasculardiseases and thrombotic events. The hemophilia cohort was slightly older (63.2[16.8]
Don’t worry—you can still access the 19th Annual CMHC sessions through our On-Demand platform, which offers 14 CME credits across four comprehensive tracks: Cardiorenal Health: Stay up-to-date with the latest on therapies for resistant hypertension, chronic kidneydisease markers, and cardiac risk assessment tools.
2–4 The studies will be well-known to nephrologists and demonstrated that angiotensin-receptor blockers (ARBs) had anti-proteinuric effects and/or slowed the decline of kidney function in patients with diabetickidneydisease. Clinicians and health care systems must be encouraged to make use of these treatments.”
BackgroundIn 2023, the American Heart Association defined the concept of cardiovascularkidneymetabolic (CKM) syndrome as a health disorder ascribed to connections among obesity, diabetes, chronic kidneydisease, and cardiovasculardisease. CKM syndrome stages 3 and 4 are considered advanced.
Cardiometabolic risk encompasses a complex spectrum of interrelated conditions, including cardiovasculardisease, type 2 diabetes, and metabolic syndrome. Key contributions: Advanced cardiac imaging (e.g., high-sensitivity troponin, NT-proBNP) in risk stratification Utilization of advanced echocardiographic techniques (e.g.,
Practical, Future-Focused Education Cardiorenal and metabolic diseases, fueled by poor lifestyle choices and health conditions, lead to type 2 diabetes, cardiovasculardisease, and chronic kidneydisease. The robust conference agenda begins with FDA updates and advancements in cardiorenal metabolic care.
Background:The Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes (SUSTAIN-6) trial showed cardiovasculardisease (CVD) benefits of semaglutide therapy in patients with type 2 diabetes mellitus (T2DM).Purpose:To year follow-up time).Results:Among
As a leader in the field of research-based cardiometabolic health education, CMHC is proud to present its CME education outcomes study at ADA (American Diabetes Association) 2024 Scientific Sessions, which offers its education-focused agenda to a wide number of healthcare practitioners from all areas of the U.S.
BackgroundThis study evaluated the effects of canagliflozin in patients with type 2 diabetes with and without prevalent cardiovasculardisease (secondary and primary prevention).Methods Canagliflozin reduced the risk of major adverse cardiovascular events (HR, 0.84 [95% CI, 0.76–0.94])
Themed “Decoding the Constellation of Cardiometabolic Health and Risk Factors,” this year’s congress will tackle the growing health threat posed by cardiometabolic diseases, affecting 47 million people in the US. Aronne, MD Expert Perspectives on Initiating and Maintaining Insulin Therapy in Type 2 Diabetes Patients Jay H.
“In addition to our new online hubs, we are continually designing live education for delivery as satellite symposia at other large conferences such as the American Heart Association or American Diabetes Association Scientific Sessions.
There are significant data that show that if you have obesity, you have a high risk of developing coronary heart disease, heart failure, type 2 diabetes (T2D) or risk factors such as hypertension and dyslipidemia. [1] 5, 6] So, it seems that once cardiovasculardisease is present, then obesity may offer some degree of protection.
PAD is a serious, progressive cardiovasculardisease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. Among those ages 65 and older, nearly 50% who underwent limb amputation died within one year after surgery, according to the 2024 Heart Disease and Stroke Statistics: A Report of U.S.
The European Society of Cardiology (ESC) Congress 2024 (August 30 – September 2, 2024) has wrapped up, delivering groundbreaking insights into cardiovasculardiseases and related conditions. Measuring eGFR and albuminuria is recommended for assessing kidneydisease in all hypertensive patients.
In addition, there are links to formal risk assessment in cardiovasculardisease. With bonus hyperlinks to NICE’s guidelines on hypertension in chronic kidneydisease and type I diabetes and type II diabetes and on and on. There are associated guidelines on hypertension in pregnancy.
The prevalence of HF risk factors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidneydisease; 22%. Overt cardiovasculardisease, which ranged from 2.1% (HF) to 13.6% (atrial fibrillation), was less common. were female, 25.6% were Black, 12.8%
Background:Racial disparities have been well described in cardiovasculardisease. Primary outcome was ischemic stroke, while secondary outcomes were all-cause mortality, heart failure, cardiogenic shock, MACE (composite of all-cause mortality, heart failure, and ischemic stroke), and acute kidney injury (AKI).Result:After
of patients had cardiovasculardisease, 10.9% diabetes, and 15.5% chronic kidneydisease. The results were reported as the pooled results using risk ratio (RR) and a confidence interval (CI) of 95%.Results:The
Bakris’s distinguished career in medicine spanned over four decades, marked by significant contributions to the fields of diabetickidneydisease, hypertension, and nephropathy progression. A Pioneering Journey: The Life and Legacy of Dr. George L. Bakris Dr. George L. Bakris was no-nonsense, yet kind-hearted as could be.
Risk factors such as smoking, chronic kidneydisease, and aging can contribute to plaque formation. The gradual loss of elasticity in arterial walls and the presence of other risk factors, such as high blood pressure and diabetes, contribute to the increased risk of cardiovasculardisease (CVD) observed in aging populations.
But resistance training hasn’t been the focus when it comes to improving cardiovascular health and preventing/reversing cardiovasculardiseases (CVDs) — that honor goes to aerobic exercise training, for which the cardiovascular benefits are well-established and vast. a higher metabolism). The answer is yes.
But resistance training hasn’t been the focus when it comes to improving cardiovascular health and preventing/reversing cardiovasculardiseases (CVDs) — that honor goes to aerobic exercise training, for which the cardiovascular benefits are well-established and vast. a higher metabolism). The answer is yes.
You’ll learn: What the Scarcity Loop is and how it guides our behaviors How ultraprocessed foods hack the Scarcity Loop About a small Amazonian tribe with virtually no incidence of cardiovasculardisease How to structure your diet to achieve success in our modern food environment And more! And this is important!
It’s been well-established that males and females respond differently to exercise. This was also observed in the current analysis — in which 58% of the training-induced responses were different between the sexes.
The study, “Association of Coronary Wall Thickening and Diminished Diastolic Function in Asymptomatic, Low CardiovascularDisease-Risk Persons Living with HIV” was published today in Radiology: Cardiothoracic Imaging , a journal of the Radiological Society of North America ( RSNA ), which issued a news summary on the study, detailed below.
SGLT-2 inhibitors, initially developed for type 2 diabetes, demonstrate profound cardiorenal and metabolic benefits. This review synthesizes evidence from clinical trials and mechanistic studies to elucidate their roles in cardiovasculardiseases, chronic kidneydisease, and non-alcoholic fatty liver disease.
Cardiovasculardisease remains the leading cause of death worldwide , claiming 18 million lives annually. 42% of adults are considered obese , increasing their risk of diabetes, hypertension, and cardiovascular issues. Moreover, cardiovasculardisease in women continues to be underrepresented and undertreated.
BackgroundCardiovascular disease(CVD) remains a significant global challenge. Asthma, which is characterized by airway hyperresponsiveness and reversible and limited airflow, plays an important role in cardiovasculardiseases.
Regular assessment of eGFR and UACR, particularly in high-risk populations such as those with diabetes or hypertension, provides crucial insights into patient health. Even small decreases in eGFRless than 60 mL/min/1.73mare associated with an increased cardiovascular risk.
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