Dr. Paddy Barrett

AUGUST 22, 2023

Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. A subsequent article will focus on the risk of late-onset dementia for those carriers of APOE4.

Cholesterol 52

Cholesterol Dementia Coronary Artery Disease Cardiovascular Disease 52

Stroke Journal

JANUARY 30, 2025

Background:White matter hyperintensities (WMH) of presumed vascular origin can be associated with vascular cognitive impairment and dementia. Stroke, Volume 56, Issue Suppl_1 , Page ADP15-ADP15, February 1, 2025. However, WMH are also seen in asymptomatic subjects. FLAIR/T1 images were segmented to create WMH masks.

Cerebrovascular Disease 40

Cerebrovascular Disease Dementia Risk Factors Cardiovascular Disease 40

Stroke Journal

FEBRUARY 1, 2024

Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovascular disease. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population.

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Diet 40

Dr. Paddy Barrett

FEBRUARY 21, 2025

Type 2 Diabetes When it comes to the increasing the risk of major chronic diseases such as cardiovascular disease, many cancers and dementia, type 2 diabetes plays a huge role. For example, people with type 2 diabetes are 10 times more likely to develop cardiovascular disease than those who do not have diabetes 10.

Obesity 81

Obesity Diabetes Cardiovascular Disease Chronic Disease 81

Dr. Paddy Barrett

SEPTEMBER 13, 2024

Insulin resistance is a major risk factor for the leading causes of death, the leading one being cardiovascular disease. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. But What Causes Insulin Resistance?

Risk Factors 106

Risk Factors Heart Disease Dementia Cardiovascular Disease 106

Circulation

NOVEMBER 14, 2024

BACKGROUND:Many studies have explored whether individual plasma protein biomarkers improve cardiovascular disease risk prediction. We sought to investigate the use of a plasma proteomics-based approach in predicting different cardiovascular outcomes.METHODS:Among 51 859 UK Biobank participants (mean age, 56.7

Cardiovascular Disease 40

Cardiovascular Disease Dementia Biomarkers Myocardial Infarction 40

Dr. Paddy Barrett

JANUARY 23, 2024

Cardiovascular disease is the leading cause of death worldwide. Over 80% of early heart disease is preventable. The real question is what the Tsimane tribe's risk factor profile looks like. As a consequence, high blood pressure is the single most important risk factor for early death worldwide 8.

Heart Disease 106

Heart Disease Blood Pressure Dementia Atherosclerosis 106

Dr. Paddy Barrett

MARCH 23, 2024

They get the diseases of ageing about 20 to 25 years later than everyone else. It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. Most adults, healthy centenarians included, will die from one of three things: Cardiovascular Disease.

Chronic Disease 106

Chronic Disease Quality of Life Dementia Cancer 106

Stroke Journal

OCTOBER 10, 2024

The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Cardiovascular diseases are the leading cause of death and disability in the United States and around the world. Stroke, Ahead of Print.

Atrial Fibrillation 75

Atrial Fibrillation Public Health Dementia Heart Failure 75

Hypertension Journal

SEPTEMBER 21, 2023

There has been considerable progress in the prevention and treatment of cardiovascular disease, reducing the population burden of cardiovascular morbidity and mortality. Here, we review these obstacles, motivated by SPRINT and the context of selecting an appropriate cognitive end point for future preventive randomized trials.

Dementia 40

Dementia Cardiovascular Interventions Blood Pressure Physiology 40

Physiologically Speaking

DECEMBER 15, 2023

But resistance training hasn’t been the focus when it comes to improving cardiovascular health and preventing/reversing cardiovascular diseases (CVDs) — that honor goes to aerobic exercise training, for which the cardiovascular benefits are well-established and vast. In short — do both!

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

But resistance training hasn’t been the focus when it comes to improving cardiovascular health and preventing/reversing cardiovascular diseases (CVDs) — that honor goes to aerobic exercise training, for which the cardiovascular benefits are well-established and vast. In short — do both!

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Stroke Journal

FEBRUARY 1, 2024

We related prevalent CVD or the individual components to the CSVD score using logistic regression analyses adjusted for age, sex, FHS cohort, time between MRI-clinic exam (model-1), and vascular risk factors (model-2).Results:In Stroke, Volume 55, Issue Suppl_1 , Page ATP15-ATP15, February 1, 2024. males), 8.4% had prevalent CVD, 4.1%

Atrial Fibrillation 40

Atrial Fibrillation Cardiovascular Disease Dementia Heart Failure 40

Cardiometabolic Health Congress

APRIL 12, 2024

Introduction: Addressing the Need for Improved LDL Management in the US There is a clear need for innovative treatments to combat cardiovascular disease (CVD). Heart disease remains the leading cause of death for men and women. However, every 40 seconds, an individual in the US suffers a heart attack.

Myocardial Infarction 64

Myocardial Infarction Cardiovascular Disease Heart Attack Heart attacks 64

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. Yes, many external factors impact these factors, but ultimately, you have significant control over all of these. Let’s look at what happens to NCD risk when these risk factors are optimised.

Cancer 97

Cancer Dementia Diabetes Cardiovascular Disease 97

Dr. Paddy Barrett

AUGUST 15, 2023

Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. Insulin resistance is unlikely to be the primary causal factor for these conditions but is likely to be a major accelerant. Subscribe now Take cardiovascular disease, for example.

Blood Pressure 52

Blood Pressure Risk Factors Diabetes Cholesterol 52

Cardiometabolic Health Congress

DECEMBER 7, 2023

Furthermore, it includes the latest recommendations which specifically address AF and thromboembolic risk assessment, anticoagulation, left atrial appendage occlusion, AF catheter or surgical ablation, and risk factor modification and AF prevention. million.

Atrial Fibrillation 111

Atrial Fibrillation Risk Factors Ablation Strokes 111

Dr. Paddy Barrett

MARCH 29, 2024

We have covered these extensively, but to reiterate, these are: Cardiovascular Disease. To most people's surprise, the leading causes of death are still heart disease and cancer. With cardiovascular disease killing about 25% more people every year than cancer. But this is global data. But equally preventable.

Cancer 106

Cancer Heart Disease Risk Factors Cardiovascular Disease 106

Dr. Smith's ECG Blog

APRIL 8, 2015

History of Cardiovascular disease (all studies): Especially any history of heart failure or structural cardiac disease, including valvular 4. Syncope without a prodrome, no precipitating factors (EGSYS) 5. —QRS Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease.

Arrhythmia 52

Arrhythmia Outcomes Risk Factors Chest Pain 52

Stroke Journal

MARCH 24, 2025

BACKGROUND:Modifiable risk factors play a central role in the development and course of neurodegenerative disorders of later life, including dementias. Stroke, Ahead of Print.

Risk Factors 40

Risk Factors Dementia Diet Education 40

Dr. Malcolm Kendrick

OCTOBER 30, 2024

The hypothesis that a raised cholesterol level causes heart disease [atherosclerotic cardiovascular disease (ASCVD)] is possibly the single most powerful idea in medicine. Which remains the single most influential study on cardiovascular disease, ever. At least some of it. It was simply a matter of time.

Cholesterol 145

Cholesterol Article Research Diet 145