Dr. Paddy Barrett

SEPTEMBER 19, 2023

I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

Dr. Paddy Barrett

FEBRUARY 21, 2025

Type 2 Diabetes When it comes to the increasing the risk of major chronic diseases such as cardiovascular disease, many cancers and dementia, type 2 diabetes plays a huge role. For example, people with type 2 diabetes are 10 times more likely to develop cardiovascular disease than those who do not have diabetes 10.

Obesity 81

Obesity Diabetes Cardiovascular Disease Chronic Disease 81

Hypertension Journal

SEPTEMBER 21, 2023

There has been considerable progress in the prevention and treatment of cardiovascular disease, reducing the population burden of cardiovascular morbidity and mortality. Here, we review these obstacles, motivated by SPRINT and the context of selecting an appropriate cognitive end point for future preventive randomized trials.

Dementia 40

Dementia Cardiovascular Interventions Blood Pressure Physiology 40

Dr. Paddy Barrett

JANUARY 23, 2024

Cardiovascular disease is the leading cause of death worldwide. Over 80% of early heart disease is preventable. Because if we can understand that, we can attempt to emulate it and also considerably delay the onset of cardiovascular disease and our risk of an early death as a consequence of it. Ann Glob Health.

Heart Disease 106

Heart Disease Blood Pressure Dementia Atherosclerosis 106

Dr. Paddy Barrett

MARCH 23, 2024

They get the diseases of ageing about 20 to 25 years later than everyone else. It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. Most adults, healthy centenarians included, will die from one of three things: Cardiovascular Disease.

Chronic Disease 106

Chronic Disease Quality of Life Dementia Cancer 106

Dr. Paddy Barrett

AUGUST 30, 2024

Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. High levels of aerobic fitness are closely linked to lower rates of future dementia 1. Regular physical activity is arguably one of the biggest factors preventing dementia. When it comes to preventing dementia, this could not be truer.

Heart Disease 111

Heart Disease Dementia Obesity Heart Attack 111

HCPLive

JANUARY 6, 2025

A study found that the protein ADM significantly mediates loneliness' link to cardiovascular disease, stroke, dementia, and mortality, emphasizing loneliness health risks.

Stroke 52

Stroke Strokes Dementia Cardiovascular Disease 52

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. For those in the ‘Ideal’ category, they were 51% less likely to have either dementia or depression. In most developed countries as of today, NCDs account for 89% of all deaths. The leading causes of death are clear.

Cancer 97

Cancer Dementia Diabetes Cardiovascular Disease 97

Stroke Journal

OCTOBER 10, 2024

The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Cardiovascular diseases are the leading cause of death and disability in the United States and around the world. Stroke, Ahead of Print.

Atrial Fibrillation 75

Atrial Fibrillation Public Health Dementia Heart Failure 75

Dr. Paddy Barrett

SEPTEMBER 13, 2024

Insulin resistance is a major risk factor for the leading causes of death, the leading one being cardiovascular disease. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. The higher the score, the higher the risk. Circulation.

Risk Factors 106

Risk Factors Heart Disease Dementia Diabetes 106

Dr. Paddy Barrett

AUGUST 23, 2024

While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. JAMA Netw Open. 2018;1(6):e183605. BMC Endocr Disord 22 , 297 (2022).

Exercise 116

Exercise Dementia Cancer Chronic Disease 116

Heart 2023 Conference

FEBRUARY 12, 2023

According to the study, eating one to three eggs each week reduces cardiovascular disease risk by 60%. In fact, the study discovered that people who consume four to seven eggs a week have a 75% decreased risk of acquiring cardiovascular disease. Early cardiovascular disease may hasten middle-aged cognitive deterioration!

Cardiovascular Disease 52

Cardiovascular Disease Dementia Plaque 52

Cardiometabolic Health Congress

JUNE 7, 2024

Ballantyne, MD , emphasized that while fellows may consider prevention “boring,” it is crucial for avoiding resource-intensive late-stage cardiovascular disease (CVD). He highlighted that cardiovascular health is essential for cognitive health, noting the common occurrence of vascular dementia.

Cardiovascular Disease 59

Cardiovascular Disease Obesity Heart Disease Risk Factors 59

Cardiometabolic Health Congress

APRIL 12, 2024

Introduction: Addressing the Need for Improved LDL Management in the US There is a clear need for innovative treatments to combat cardiovascular disease (CVD). Heart disease remains the leading cause of death for men and women. However, every 40 seconds, an individual in the US suffers a heart attack.

Myocardial Infarction 64

Myocardial Infarction Cardiovascular Disease Heart Attack Heart attacks 64

Dr. Paddy Barrett

AUGUST 22, 2023

Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. A subsequent article will focus on the risk of late-onset dementia for those carriers of APOE4.

Cholesterol 52

Cholesterol Dementia Coronary Artery Disease Cardiovascular Disease 52

Open Heart

APRIL 22, 2022

Objectives Elevated low-density lipoprotein cholesterol (LDL-C) increases the risk of recurrent cardiovascular disease (CVD) events. We used the Secondary Manifestations of Arterial Disease-Reduction of Atherothrombosis for Continued Health (SMART-REACH) model to estimate the expected benefit of up-titrating LLT. to –0.9)

Stroke 52

Stroke Strokes Cholesterol Dementia 52

Stroke Journal

JANUARY 30, 2025

Cognitive impairment (CGI) is common in patients with cardiovascular diseases, contributing to morbidity and mortality, especially among people over the age of 64. Cardiogenic dementia has been suggested to characterize patients suffering from cognitive decline after heart disease.

Dementia 40

Dementia Myocardial Infarction Ischemia Cardiovascular Disease 40

Stroke Journal

JANUARY 30, 2025

Introduction:Covert brain infarcts (CBIs) are associated with risk of stroke and dementia. The Atherosclerotic Cardiovascular Disease (ASCVD) risk score (>7.5%) had higher sensitivity (0.96) but similar accuracy (0.66) in comparison to the CBI scores. Stroke, Volume 56, Issue Suppl_1 , Page ADP22-ADP22, February 1, 2025.

Risk Factors 40

Risk Factors Cardiovascular Disease Dementia Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionPatients with cognitive impairment often have a history of cardiovascular disease (CVD) or multiple cardiovascular risk factors (CRFs) such as hypertension, obesity, and hypercholesterolemia. The literature reports that CVD with CRFs may increase the risk of developing vascular dementia and Alzheimer’s Disease.

Risk Factors 40

Risk Factors Dementia Chest Pain Quality of Life 40

Stroke Journal

JANUARY 30, 2025

Background:White matter hyperintensities (WMH) of presumed vascular origin can be associated with vascular cognitive impairment and dementia. Stroke, Volume 56, Issue Suppl_1 , Page ADP15-ADP15, February 1, 2025. However, WMH are also seen in asymptomatic subjects. FLAIR/T1 images were segmented to create WMH masks.

Cerebrovascular Disease 40

Cerebrovascular Disease Dementia Risk Factors Cardiovascular Disease 40

Stroke Journal

FEBRUARY 1, 2024

Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovascular disease. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population.

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Diet 40

Physiologically Speaking

DECEMBER 15, 2023

But resistance training hasn’t been the focus when it comes to improving cardiovascular health and preventing/reversing cardiovascular diseases (CVDs) — that honor goes to aerobic exercise training, for which the cardiovascular benefits are well-established and vast. The answer is yes.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

But resistance training hasn’t been the focus when it comes to improving cardiovascular health and preventing/reversing cardiovascular diseases (CVDs) — that honor goes to aerobic exercise training, for which the cardiovascular benefits are well-established and vast. The answer is yes.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

FEBRUARY 26, 2024

You’ll learn: What the Scarcity Loop is and how it guides our behaviors How ultraprocessed foods hack the Scarcity Loop About a small Amazonian tribe with virtually no incidence of cardiovascular disease How to structure your diet to achieve success in our modern food environment And more! And this is important!

Diet 52

Diet Cardiovascular Disease Exercise Research 52

Dr. Paddy Barrett

AUGUST 15, 2023

Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. Subscribe now Take cardiovascular disease, for example. Insulin resistance is unlikely to be the primary causal factor for these conditions but is likely to be a major accelerant.

Blood Pressure 52

Blood Pressure Risk Factors Diabetes Cholesterol 52

Circulation

NOVEMBER 14, 2024

BACKGROUND:Many studies have explored whether individual plasma protein biomarkers improve cardiovascular disease risk prediction. We sought to investigate the use of a plasma proteomics-based approach in predicting different cardiovascular outcomes.METHODS:Among 51 859 UK Biobank participants (mean age, 56.7

Cardiovascular Disease 40

Cardiovascular Disease Dementia Biomarkers Myocardial Infarction 40

Cardiometabolic Health Congress

DECEMBER 7, 2023

Published on November 30, 2023, in the Journal of the American College of Cardiology, these new guidelines are based on a comprehensive literature review from May 2022 to November 2022, and provide important recommendations to clinicians caring for patients with or at risk of developing cardiovascular disease (CVD). million.

Atrial Fibrillation 111

Atrial Fibrillation Risk Factors Ablation Stroke 111

Dr. Paddy Barrett

MARCH 29, 2024

We have covered these extensively, but to reiterate, these are: Cardiovascular Disease. To most people's surprise, the leading causes of death are still heart disease and cancer. With cardiovascular disease killing about 25% more people every year than cancer. But this is global data.

Cancer 106

Cancer Heart Disease Risk Factors Cardiovascular Disease 106

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP15-ATP15, February 1, 2024.

Atrial Fibrillation 40

Atrial Fibrillation Cardiovascular Disease Dementia Heart Failure 40

Dr. Paddy Barrett

MARCH 12, 2024

Improved levels of mitochondria efficiency are linked to lower rates of the major medical conditions likely to cause early death, namely, cardiovascular disease, cancer and dementia 2. High aerobic fitness levels, as measured by V02, are consistently linked to a longer life 1.

Exercise 98

Exercise Dementia Cancer Cardiovascular Disease 98

Stroke Journal

DECEMBER 5, 2024

Participants underwent brain magnetic resonance imaging scans every 3 to 4 years between 2005 and 2016. Cerebral blood flow (CBF) was measured through 2-dimensional phase-contrast magnetic resonance imaging; the cerebrovascular resistance index (CVRi) was defined as the ratio of mean arterial blood pressure to total CBF.

Blood Pressure 40

Blood Pressure Dementia Cardiovascular Disease Diabetes 40

Dr. Smith's ECG Blog

APRIL 8, 2015

History of Cardiovascular disease (all studies): Especially any history of heart failure or structural cardiac disease, including valvular 4. Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. Age greater than 65 (Sarasin and STePS) 3.

Arrhythmia 52

Arrhythmia Outcomes Chest Pain Risk Factors 52

Dr. Malcolm Kendrick

OCTOBER 30, 2024

The hypothesis that a raised cholesterol level causes heart disease [atherosclerotic cardiovascular disease (ASCVD)] is possibly the single most powerful idea in medicine. Which remains the single most influential study on cardiovascular disease, ever. At least some of it. It was simply a matter of time.

Cholesterol 145

Cholesterol Article Research Diet 145

Stroke Journal

MARCH 24, 2025

BACKGROUND:Modifiable risk factors play a central role in the development and course of neurodegenerative disorders of later life, including dementias.

Risk Factors 40

Risk Factors Dementia Diet Education 40