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A gentler approach to monitor for heart transplant rejection

Frontiers in Cardiovascular Medicine

Despite developments in circulating biomarker and imaging technology in the assessment of cardiovascular disease, the surveillance and diagnosis of heart transplant rejection has continued to rely on histopathologic interpretation of the endomyocardial biopsy.

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Cardiovascular Management of Patients Undergoing Hematopoietic Stem Cell Transplantation: From Pretransplantation to Survivorship: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with cardiovascular diseases. Cardiovascular evaluations are crucial in pretransplantation assessments, but guidelines are lacking.

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Using Stem Cell-derived Heart Muscle Cells to Advance Heart Regenerative Therapy

DAIC

Image courtesy of Hideki Kobayashi from Shinshu University milla1cf Tue, 04/30/2024 - 12:53 April 30, 2024 — Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high.

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Abstract Sa1109: Aerobic Capacity of Adults with Fontan Palliation: Disease-specific Reference Values and Relationship to Outcomes

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page ASa1109-ASa1109, November 12, 2024. However, the assessment of aerobic capacity in this population still relies on comparisons with people without cardiovascular disease, rather than comparison with the expected aerobic capacity of other Fontan patients. 15.2 - 23.9)

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Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation

Circulation

Circulation, Ahead of Print. BACKGROUND:Clonal hematopoiesis of indeterminate potential (CHIP), a common age-associated phenomenon, associates with increased risk of both hematological malignancy and cardiovascular disease.

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Highlights of ACC 2024

Cardiology Update

Investigators assessed if empagliflozin could lower the risk of hospitalization for heart failure (HF) or death from cardiovascular disease (CVD). The Impella CP is a catheter-based, axial flow pump that pumps blood directly from the left ventricle into the circulation. It is able to deliver 3.5L/min

Angina 52
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Abstract 4139383: Non-Inferiority Of Extracorporeal Photopheresis To Immunosuppression Therapy In Heart Transplantation Rejection

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4139383-A4139383, November 12, 2024. Background:Immunosuppressive (IS) therapy is currently used as first-line treatment for heart transplant (HTx) rejection. However, they are not without complications, and less toxic therapies are needed. years, males: 58.4%).