This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. But what if there's more to the picture than just cholesterol?
More than 70% of American Indian young adults aged 20-39 and 50% of American Indian teens have cholesterol levels or elevated fat in the blood that put them at risk for cardiovasculardisease, a new study suggests.
milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo.
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovasculardisease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.
A recently unveiled cardiovasculardisease risk calculator that measures a patient's risk for heart attack and stroke is better calibrated and more precise than its previous version, but if current treatment guidelines for cholesterol and blood pressure therapy remain unchanged, the new calculator may have unintended consequences, according to research (..)
Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.
Researchers have identified a new pathway that contributes to cardiovasculardisease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease.
Despite this, including them to a person’s food regimen can assist raise “suitable” ldl cholesterol degrees. However, they'll now no longer assist decrease “awful” ldl cholesterol with out extra food regimen changes. Some declare it could additionally decrease low-density lipoprotein (LDL) ldl cholesterol, called awful ldl cholesterol.
The 10 and 30year risks of total CVD, atherosclerotic CVD, coronary heart disease, stroke, and heart failure (HF) were estimated for patients without CVD history at each time point (n=1242910), using the social deprivation indexenhanced Predicting Risk of CardiovascularDisease EVENTs equations.
adults—and more than 2 in 5 adults aged 60 years and older—have elevated triglycerides, also known as hypertriglyceridemia , putting them at an increased risk for heart attacks and stroke. It is well known that high levels of low-density lipoprotein (LDL) cholesterol, known as the “bad” cholesterol, heighten cardiovascular risk.
Objectives Elevated low-density lipoprotein cholesterol (LDL-C) increases the risk of recurrent cardiovasculardisease (CVD) events. We examined use of lipid-lowering therapy (LLT) following ischaemic stroke, and estimated benefits from guideline-based up-titration of LLT. and women (coefficient –5.1 to –0.9)
Exercise in a regular pattern is one of the important life style modifications which everyone can adopt to prevent or delay cardiovasculardisease. Exercise helps in various ways for prevention of cardiovasculardisease. Maintaining normal blood pressure also reduces the risk of stroke and myocardial infarction.
BackgroundElevated lowdensity lipoprotein cholesterol is a risk factor for atherosclerotic cardiovasculardisease, including acute ischemic stroke (AIS), due to large and smallvessel disease. Lack of prestroke LLT use was associated with more severe stroke symptoms upon presentation.
Background and aims Epidemiology of atherosclerotic cardiovasculardisease might be different in patients with polygenic hypercholesterolemia plus high levels (≥30 mg/dl) of Lp(a) (H-Lpa) than in those with polygenic hypercholesterolemia alone (H-LDL). The median duration of follow-up was 10 years (IQR 3–16). 3.17, P = 0.006).
Methods A multicentre cross-sectional epidemiological study to estimate the prevalence of elevated Lp(a) in patients with a history of myocardial infarction, ischaemic stroke or peripheral artery disease conducted at 949 sites in 48 countries in North America, Europe, Asia, South America, South Africa and Australia between April 2019 and July 2021.
It encompasses several factors, including the strength and efficiency of the heart, the flexibility and health of the blood vessels, and the ability of the cardiovascular system to deliver oxygen and nutrients to the body’s tissues. Moreover, a healthy heart contributes to improved overall fitness, endurance, and quality of life.
Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023. The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease.
Raised lipoprotein(a) (Lp[a]) cholesterol is highly prevalent affecting 1 in 5 individuals and is also frequently associated with the inherited condition familial hypercholesterolaemia (FH).
Addressing an Unmet Need in Pediatric Patients with HeFH Heterozygous familial hypercholesterolemia (HeFH) affects about 1 in 313 people—characterized by dangerously high low-density lipoprotein cholesterol (LDL-C) levels. Untreated, it can trigger early heart disease.
26th August 2022 And so, after a great deal of faffing about, my article on cardiovasculardisease ‘Assessing cardiovasculardisease: looking beyond cholesterol’ has been made free to view. Eric Westman is a staunch ally in the crusade to look at different causal models of cardiovasculardisease.
Stroke, Volume 55, Issue Suppl_1 , Page A133-A133, February 1, 2024. Mendelian randomization (MR) studies suggest a causal effect of Fe status on ischemic stroke (IS).
reduction in low-density lipoprotein (LDL) cholesterol, on average, six months after starting treatment. LDL or “bad” cholesterol contributes to the development of fatty deposits in the arteries, which raises the risk of heart attacks, strokes and other forms of heart disease.
The overwhelming prevailing opinion among Cardiologists (including from our own Heartbeat Cardiology team w/hundreds of combined years of experience treating cardiovasculardisease) is that people can benefit from adopting a Mediterranean diet, so let’s dive in and understand what that really means.
I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. A therapy that has been proven repeatedly to reduce the probability of heart attacks and strokes in multiple double-blind randomised controlled studies 1. Let’s break this down.
High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heart attacks and strokes. Patients’ average triglyceride level at baseline was about 900 mg/dL. Patients were randomly assigned to one of four groups.
An elevated Lp(a) is the most common genetic cholesterol disorder impacting 10-20% of the population. Everyone should have an Lp(a) blood test at least once, but this is an absolutely must-do test if you have an early family history of heart disease. Small Interfering RNA to Reduce Lipoprotein(a) in CardiovascularDisease.
Stroke, Volume 55, Issue Suppl_1 , Page A10-A10, February 1, 2024. Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovasculardisease. Participants with prior stroke, transient ischemic attack (TIA) or myocardial infarction (MI) were excluded.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Utilizing a novel integration of FDG and NaF PET/CT imaging, our study explores the link between cardiovascular risk factors and regional cerebral metabolism.MethodsWe compared 79 healthy controls (mean age 44.5 ± 13.8
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovasculardisease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.
Eighty percent of heart attacks and strokes are preventable. partially because its key risk factor, high blood pressure, is a ‘silent killer,’ and most patients have no symptoms before their first heart attack or stroke. Change in blood pressure (BP), LDL cholesterol, and weight were evaluated from baseline to follow up.
adults have high cholesterol, according to the Centers for Disease Control and Prevention (CDC). Untreated, high cholesterol can lead to heart disease and stroke, which are two of the top causes of death in the U.S. Nearly two in five U.S.
In simple terms, the higher your blood pressure, the higher the risk of a future heart attack or stroke. Even systolic (Top number) blood pressures of greater than 90 mmHg increase the risk of future heart disease 2. The Cholesterol Secrets Masterclass? Cholesterol Secrets Masterclass. This is it. No fancy procedures.
Every year, the AHA reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors. In 2010, the AHA released a 2020 goal to improve the CV health of all Americans by 20%, while reducing CVD and stroke deaths by 20%. Excluding hypertension (CHD, HF, and stroke only), just 9.9%
Atherosclerotic cardiovasculardisease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
The 2023 Almanac results derived from the Global Burden of Disease (GBD) and spanning 1990 to 2022, were recently published in the Journal of American College of Cardiology. The vision of heart-healthy, stroke-free, and thriving communities worldwide is achievable through proactive measures and collaborative efforts.
February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovasculardisease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. per 1,000* - 122.4
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovasculardisease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.
The new model, which ultimately could change how cardiovasculardisease risk is assessed in doctors’ offices around the world, is described in a paper published online January 29 in the Journal of the American College of Cardiology. Parameters of the new model are available in the paper supplements.
Zerlasiran is a siRNA (short interfering RNA) designed to lower the body’s production of Lp(a), a key genetic risk factor for cardiovasculardisease affecting up to 20% of the world’s population. In this case, it aims to ‘silence’ LPA, a gene that tells the body to make a specific protein that is only found in Lp(a).
These are true innovators who propose novel approaches to major research challenges in the areas of heart disease, stroke and brain health. Loscalzo’s research will focus on the link between heart disease and certain foods, or chemicals naturally contained in foods.
A new peer-reviewed study published in the Journal of the American Heart Association , JAHA, found that Hello Heart’s digital heart health program was associated with reductions in blood pressure (BP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and weight. statins). .
Introduction Statins remain the first-line treatment for secondary prevention of cardiovascular (CV) events, with lowering of low-density lipoprotein cholesterol (LDL-C) being their therapeutic target. Recurrent stroke occurs in up to 19% of patients seven years after a first cerebrovascular event.
Specifically, LODOCO reduces cardiac event risk in adult patients with established atherosclerotic cardiovasculardisease (ASCVD) by an additional 31% as compared to placebo. Caristo’s CaRi-Heart technology applies advanced AI algorithms to routine cardiac CT scans to visualize and quantify coronary inflammation.
Introduction:Historically, Middle-Eastern (ME) immigrants have been aggregated with Non-Hispanic White (NHW) individuals, masking disparities in cardiovasculardiseases (CVD). Circulation, Volume 150, Issue Suppl_1 , Page A4139303-A4139303, November 12, 2024. NHW&6.8% years, [SD=18.9]) with 51% being female. NHW&6.8%
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content