Journal of Clinical Investigation - Cardiology

MARCH 1, 2024

Patients with chronic inflammatory disorders such as psoriasis have an increased risk of cardiovascular disease and elevated levels of LL37, a cathelicidin host defense peptide that has both antimicrobial and proinflammatory properties.

Atherosclerosis 122

Atherosclerosis Cholesterol Cardiovascular Disease Plaque 122

DAIC

MARCH 31, 2025

mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

Dr. Paddy Barrett

FEBRUARY 7, 2025

Over a long enough time frame, pretty much everyone will get heart disease. By the time you get to age 80, you will almost certainly have evidence of plaque in your coronary arteries - you will have heart disease. But remember: Heart disease doesn’t kill people. Heart disease happens slowly. Good Nutrition.

Heart Disease 106

Heart Disease Heart Attack Heart attacks Blood Pressure 106

Dr. Paddy Barrett

FEBRUARY 27, 2024

The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time. The answer: Risk Factors. The answer.

Risk Factors 111

Risk Factors Heart Disease Heart Attack Heart attacks 111

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide. The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Journal of the American Heart Association

MARCH 6, 2024

We used carotid ultrasounds to detect plaque at baseline and follow‐up in 2006 to 2009 (median follow‐up=5.5 had low‐density lipoprotein cholesterol ≥160 mg/dL, which is higher than the recommended threshold for lifestyle or medical interventions in young adults of 20 to 39 years old. Lipids were measured after a 12‐hour fast.

Plaque 75

Plaque Cholesterol Ultrasound Risk Factors 75

DAIC

APRIL 7, 2024

It is well known that high levels of low-density lipoprotein (LDL) cholesterol, known as the “bad” cholesterol, heighten cardiovascular risk. A total of 154 patients (median age 62 years, 42% women) with high triglyceride levels and other risk factors for cardiovascular disease participated in the study at 24 sites in the U.S.

Cholesterol 116

Cholesterol Heart Attack Heart attacks Myocardial Infarction 116

DAIC

JANUARY 25, 2024

Specifically, LODOCO reduces cardiac event risk in adult patients with established atherosclerotic cardiovascular disease (ASCVD) by an additional 31% as compared to placebo. Caristo’s CaRi-Heart technology applies advanced AI algorithms to routine cardiac CT scans to visualize and quantify coronary inflammation.

Heart Attack 110

Heart Attack Heart attacks Technology Cardiovascular Disease 110

JAMA Cardiology

MARCH 4, 2025

This is because the test is widely available, fast, highly reproducible, low radiation, directly reflective of total coronary plaque burden, and highly predictive of future atherosclerotic cardiovascular disease (ASCVD) events.

Plaque 59

Plaque Cholesterol Cardiovascular Disease 59

All About Cardiovascular System and Disorders

APRIL 30, 2024

Exercise in a regular pattern is one of the important life style modifications which everyone can adopt to prevent or delay cardiovascular disease. Exercise helps in various ways for prevention of cardiovascular disease. High density lipoprotein cholesterol in the blood increases with regular exercise.

Exercise 52

Exercise Heart Disease Blood Pressure Cholesterol 52

Frontiers in Cardiovascular Medicine

MARCH 21, 2024

The Wnt signaling pathway is thought to play an active role in the pathogenesis of several cardiovascular diseases; however, a better understanding of this system in atherosclerosis is yet to be unraveled.

Atherosclerosis 64

Atherosclerosis Plaque Cholesterol Cardiovascular Disease 64

Dr. Paddy Barrett

JANUARY 23, 2024

Cardiovascular disease is the leading cause of death worldwide. Over 80% of early heart disease is preventable. However, most adults will start to develop advanced plaque in their coronary arteries early in life. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque.

Heart Disease 105

Heart Disease Blood Pressure Dementia Atherosclerosis 105

Physiologically Speaking

FEBRUARY 23, 2024

However, a series of recent studies in mice and in humans reveals that protein may promote a cascade of events in the body that lead to cardiovascular disease. All of this is true, yet some observational studies (with all of their inherent flaws) have associated a high (animal) protein intake with cardiovascular disease risk.

Physiology 111

Physiology Atherosclerosis Diet Cardiovascular Disease 111

GEMMS

NOVEMBER 22, 2023

By understanding the significance of cardiovascular health, we can make informed choices and adopt lifestyle habits that promote a strong and resilient heart. Risk factors for cardiovascular disease Understanding the risk factors for cardiovascular disease is crucial for maintaining optimal cardiovascular health.

Blood Pressure 52

Blood Pressure Cholesterol Diet Exercise 52

Dr. Malcolm Kendrick

AUGUST 26, 2022

26th August 2022 And so, after a great deal of faffing about, my article on cardiovascular disease ‘Assessing cardiovascular disease: looking beyond cholesterol’ has been made free to view. Eric Westman is a staunch ally in the crusade to look at different causal models of cardiovascular disease.

Cardiovascular Disease 40

Cardiovascular Disease Cholesterol Article Plaque 40

DAIC

APRIL 7, 2024

High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heart attacks and strokes. An estimated 1 in 5 U.S. Patients’ average triglyceride level at baseline was about 900 mg/dL.

Heart Attack 110

Heart Attack Heart attacks Plaque Cholesterol 110

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Circulation

NOVEMBER 11, 2024

Background:The role of immune suppressive microenvironment, promulgated by the presence of Myeloid Derived Suppressor Cells (MDSC) have been the major focus of research delineating the underlying mechanisms of cardiovascular diseases (CVD). 3ng/day for 15 days).M-MDSCs Further, CCR5 modulation expanded IL10+M-MDSCin vivo.

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Diet 40

Heart 2023 Conference

APRIL 20, 2022

Avocado consumption of at least two servings per week is linked to a lower risk of cardiovascular disease. Harvard University Heart Letter) A clinical polygenic risk score test for diseases ranging from atrial fibrillation (AFib) to breast cancer was piloted by scientists.

Pulmonary 52

Pulmonary Hypertension AFIB COVID-19 52

Stroke Journal

NOVEMBER 9, 2023

This article describes the pathway from gene discovery to novel therapeutic approaches that are now entering man.HDAC9expression is elevated in human atherosclerotic plaque, while in animal and cellular models, reducing HDAC9 (histone deacetylase 9) protein is associated with reduced disease.

Stroke 40

Stroke Strokes Atherosclerosis Coronary Artery Disease 40

Journal of the American Heart Association

NOVEMBER 23, 2023

BackgroundPatients with nonalcoholic fatty liver disease are at increased risk to develop atherosclerotic cardiovascular diseases. Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023.

Aortic 40

Aortic Aneurysm Plaque Cholesterol 40

Dr. Paddy Barrett

MAY 31, 2024

The mistake most people make when it comes to heart disease is thinking that when someone has a heart attack that, the condition of ‘heart disease’ just appeared. But heart disease presents slowly. The amount of plaque is an excellent predictor of the risk of heart attack over the following 10-year period 1.

Heart Disease 95

Heart Disease Plaque Heart Attack Heart attacks 95

Frontiers in Cardiovascular Medicine

FEBRUARY 16, 2024

Introduction Atherosclerosis is a chronic inflammatory disease caused by the deposition of lipids within the artery wall. During atherogenesis, efficient autophagy is needed to facilitate efferocytosis and cholesterol efflux, limit inflammation and lipid droplet buildup, and eliminate defective mitochondria and protein aggregates.

Atherosclerosis 64

Atherosclerosis Plaque Diet Cholesterol 64

Cardiometabolic Health Congress

NOVEMBER 22, 2024

Another promising advancement is MK-0616 , an oral PCSK9 inhibitor in Phase 3 trials, showing a significant reduction in LDL cholesterol, which provides a more convenient alternative to current injection-based therapies​.

Blood Pressure 59

Blood Pressure Obesity Preserved Ejection Fraction Coronary Artery Disease 59