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Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heartattack, and more, making it the focus of many heart health campaigns. But what if there's more to the picture than just cholesterol?
Only when you have a clear idea of those three factors can you decide whether or not to take a medication to lower your LDL cholesterol. I use statins in the question posed above because that is what most people think and, in fact, what they will start with when looking to lower their LDL cholesterol with a medication. Not zero risk.
More than 70% of American Indian young adults aged 20-39 and 50% of American Indian teens have cholesterol levels or elevated fat in the blood that put them at risk for cardiovasculardisease, a new study suggests.
A recently unveiled cardiovasculardisease risk calculator that measures a patient's risk for heartattack and stroke is better calibrated and more precise than its previous version, but if current treatment guidelines for cholesterol and blood pressure therapy remain unchanged, the new calculator may have unintended consequences, according to research (..)
milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heartattack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo.
Eighty percent of heartattacks and strokes are preventable. partially because its key risk factor, high blood pressure, is a ‘silent killer,’ and most patients have no symptoms before their first heartattack or stroke. The monitor and app recorded blood pressure, heart rate, and the appearance of irregular heartbeat.
Atherosclerotic cardiovasculardisease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
Researchers have identified a new pathway that contributes to cardiovasculardisease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heartdisease.
By the time you get to age 80, you will almost certainly have evidence of plaque in your coronary arteries - you will have heartdisease. But remember: Heartdisease doesn’t kill people. Heartattacks do. And while heartattacks happen suddenly. Heartdisease happens slowly.
In simple terms, the higher your blood pressure, the higher the risk of a future heartattack or stroke. Even systolic (Top number) blood pressures of greater than 90 mmHg increase the risk of future heartdisease 2. The Cholesterol Secrets Masterclass? Cholesterol Secrets Masterclass. This is it.
In my opinion, or should I say ‘allegedly’ what actually happened here was that Barney Calman had heard from various cardiology experts that cholesterol and statin ‘deniers’ were causing people to stop taking their drugs. As a writer and lecturer, he has a specialist interest in the epidemiology of cardiovasculardisease.
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovasculardisease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heartdisease, said Matthew J.
When you look at the risk of having a heartattack, it is true that the older you are, the greater the odds of having a heartattack 1. While only 1-2% of those having a heartattack are less than 65 years of age, 1-2% of this very large number means a LOT of heartattacks. So far, so good.
The Minneapolis Heart Institute Foundation (MHIF) is presenting leading research focused on trends in ST-elevation myocardial infarction (STEMI), the most severe form of a heartattack, at the American College of Cardiology’s Annual Scientific Session (ACC.24), 24), being held April 6-8 in Atltanta, GA.
The new model, which ultimately could change how cardiovasculardisease risk is assessed in doctors’ offices around the world, is described in a paper published online January 29 in the Journal of the American College of Cardiology. Parameters of the new model are available in the paper supplements.
Zerlasiran is a siRNA (short interfering RNA) designed to lower the body’s production of Lp(a), a key genetic risk factor for cardiovasculardisease affecting up to 20% of the world’s population. In this case, it aims to ‘silence’ LPA, a gene that tells the body to make a specific protein that is only found in Lp(a).
A new peer-reviewed study published in the Journal of the American Heart Association , JAHA, found that Hello Heart’s digital heart health program was associated with reductions in blood pressure (BP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and weight. statins). .
But What About Stress & HeartDisease? When stress is included in the risk factor profile for a future heartattack, it comes in third on the list after abnormal cholesterol and smoking 1. 5 Effects of stress on the development and progression of cardiovasculardisease. The link is real.
Exercise prevents and reverses cardiovasculardisease, but whether high-intensity exercise training (HIIT) is safe and effective for adults after minimally invasive heart surgery is unknown. Exercise is a wonder drug for cardiovasculardisease (CVD) prevention and reversal. HbA1c also didn’t change.
In short, we were effectively accused of being liars, and ‘ purveyors of misinformation ’ about statins (drugs that lower LDL/cholesterol). Because of our lies hundreds of thousands of people had stopped taking statins, resulting in (potentially) many thousands of heartattacks, strokes and deaths.
Maintaining cardiovascular health reduces the risk of developing various heartdiseases, including heartattack, stroke, and high blood pressure. Moreover, a healthy heart contributes to improved overall fitness, endurance, and quality of life.
A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heartattack, stroke and death for people with Peripheral Artery Disease (PAD).
High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heartattacks and strokes. Patients’ average triglyceride level at baseline was about 900 mg/dL.
reduction in low-density lipoprotein (LDL) cholesterol, on average, six months after starting treatment. LDL or “bad” cholesterol contributes to the development of fatty deposits in the arteries, which raises the risk of heartattacks, strokes and other forms of heartdisease.
Cardiovasculardisease remains the leading cause of death worldwide, and it poses a significant threat to men’s health. While cardiovascular risk affects both genders, men often face unique challenges and factors that increase their susceptibility.
I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. A therapy that has been proven repeatedly to reduce the probability of heartattacks and strokes in multiple double-blind randomised controlled studies 1. Let’s break this down.
An elevated Lp(a) is the most common genetic cholesterol disorder impacting 10-20% of the population. Everyone should have an Lp(a) blood test at least once, but this is an absolutely must-do test if you have an early family history of heartdisease. J Am Coll Cardiol. 2021 Aug 3;78(5):421-433. J Am Coll Cardiol.
Many of the commonest and most deadly diseases afflicting humanity would be picked up early, then treated. People at risk of cardiovasculardisease would have their cholesterol levels checked. The aim is to reduce death and damage from nasty things such as heartattacks and strokes. The aim of all this?
Share JUPITER In 2008 a landmark paper was published showing that in people without cardiovasculardisease and relatively normal LDL-cholesterol (<3.4 mmol/l or 130 mg/dl), the use of rosuvastatin 20mg significantly reduced the likelihood of major cardiovascular events 1. Share But what about events? What To Do?
Discovering discrepancies in a major published trial from the pharma-academic complex would be a boost to those seeking to force trial data to be public, and that is exactly what a group of investigators attempted to do with a major cholesterol lowering trial published in 2017. Cholesterol lowering is big business. billion dollars.
Getty Images milla1cf Mon, 04/29/2024 - 13:06 April 29, 2024 — Women with heartdisease are less often treated with cholesterol-lowering drugs than men, according to research presented today at ESC Preventive Cardiology 2024 , a scientific congress of the European Society of Cardiology ( ESC ).1 80 years or older).
adults—and more than 2 in 5 adults aged 60 years and older—have elevated triglycerides, also known as hypertriglyceridemia , putting them at an increased risk for heartattacks and stroke. It is well known that high levels of low-density lipoprotein (LDL) cholesterol, known as the “bad” cholesterol, heighten cardiovascular risk.
Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heartattack, or stroke in adults with known heartdisease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.
They will also selectively support clinical research involving the CaRi-Heart technology for coronary inflammation diagnostics and LODOCO 0.5 Caristo shares Agepha Pharma’s passion for fighting coronary inflammation, which is one of the primary drivers of heartattack risks,” said Frank Cheng , CEO of Caristo Diagnostics. “We
The mistake most people make when it comes to heartdisease is thinking that when someone has a heartattack that, the condition of ‘heartdisease’ just appeared. Heartattacks present suddenly. But heartdisease presents slowly. CT Coronary Angiogram.
Females have about a 10-year advantage over males when it comes to the onset of cardiovasculardisease 1. On average, females present with heartattacks later in life. Because of these facts, females are considered to be ‘ lower risk ’ when it comes to cardiovasculardisease. Earlier in life.
Introduction:Historically, Middle-Eastern (ME) immigrants have been aggregated with Non-Hispanic White (NHW) individuals, masking disparities in cardiovasculardiseases (CVD). Circulation, Volume 150, Issue Suppl_1 , Page A4139303-A4139303, November 12, 2024. NHW&6.8% years, [SD=18.9]) with 51% being female. NHW&6.8%
When they inevitably have a heartattack, the physician and the patient are often surprised, but if they had looked, they might have seen where that risk was coming from and what to have done about it. It is genetically mediated, so if you have an early family history of heartdisease, this is something to consider 2.
Erectile dysfunction (ED) is a common concern among men, especially those dealing with cardiovasculardisease. The connection between heart health, vascular risk factors, and sexual function is well-documented, with poor cardiovascular health often leading to or exacerbating erectile issues.
I, Dr Malcolm Kendrick, with or without other co-conspirators, would be accused of spreading misinformation about cholesterol and statins. This misinformation would have resulted in many thousands of people giving up their medication and suffering heartattacks and strokes as a result. Why do these attacks happen?
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