Science Daily - Heart Disease

DECEMBER 19, 2024

Researchers have discovered that certain components of so-called 'good' cholesterol -- high-density lipoproteins (HDL) -- may be associated with an increased prevalence of cardiovascular disease.

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DAIC

APRIL 7, 2024

milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo.

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Medical Xpress - Cardiology

FEBRUARY 12, 2025

The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai researcher of a Phase II trial.

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Becker's Hospital Review - Cardiology

FEBRUARY 20, 2024

Niacin , a common B vitamin once recommended to patients as a way to help lower cholesterol, has been linked to cardiovascular disease, Cleveland Clinic researchers announced Feb.

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Science Daily - Heart Disease

NOVEMBER 18, 2024

Salk scientists have tracked the flow of trans fats using mouse models to describe the molecular mechanisms that cause trans fats to promote atherosclerotic cardiovascular disease (ASCVD), explaining how industrially produced trans-unsaturated fatty acids in our food significantly promote ASCVD and encouraging lawmakers to impose regulations on the (..)

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JAMA Cardiology

JULY 2, 2024

This randomized clinical trial evaluates the safety and efficacy of lerodalcibep vs placebo in reduction of low-density lipoprotein cholesterol in patients with or at risk of cardiovascular disease.

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JAMA Cardiology

NOVEMBER 19, 2024

This systematic review and individual patient data meta-analysis investigates the association of an alternative low-density lipoprotein (LDL) strategy with differences in long-term efficacy and safety in patients with atherosclerotic cardiovascular disease (ASCVD) compared with a high-intensity statin strategy.

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Medical Xpress - Cardiology

DECEMBER 19, 2024

Houston Methodist researchers have discovered that certain components of so-called "good" cholesterolhigh-density lipoproteins (HDL)may be associated with an increased prevalence of cardiovascular disease.

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DAIC

APRIL 24, 2024

The app also recorded other significant heart health risk factors, such as cholesterol, weight, and physical activity via integration with external sources including electronic medical records and fitness trackers. Change in blood pressure (BP), LDL cholesterol, and weight were evaluated from baseline to follow up.

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The British Journal of Cardiology

DECEMBER 3, 2024

This year, the cholesterol charity took on an international theme, looking at the global cardiovascular disease (CVD) prevention picture. There was also a particular focus on women and CVD disease, alongside a review of how familial hypercholesterolaemia (FH) care has advanced in recent decades.

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Cardiology Update

JANUARY 24, 2024

The 2023 Almanac results derived from the Global Burden of Disease (GBD) and spanning 1990 to 2022, were recently published in the Journal of American College of Cardiology. The post Global Trends in Cardiovascular Diseases: Insights from the 2023 Almanac appeared first on Cardiology Update. Original article: Mensah GA et al.

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DAIC

FEBRUARY 1, 2024

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. per 1,000* - 122.4

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The New England Journal of Medicine

AUGUST 30, 2024

Measurement of low-density lipoprotein cholesterol, high-sensitivity C-reactive protein, and lipoprotein(a) predicted the 30-year cardiovascular disease risk among women enrolled in the Women’s Health Study.

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Cardiovascular Diabetology

JANUARY 1, 2025

The analyses of longitudinal changes in remnant cholesterol (RC) and cardiovascular disease (CVD) remains are limited. The objective of the study was to investigate the associations of longitudinal changes in.

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Cardiovascular Diabetology

MARCH 9, 2025

Cardiovascular disease (CVD) represents a significant global health challenge, characterized by high incidence rates and substantial morbidity and mortality. A newer index, the Cholesterol, High-Density Lipopr.

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DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

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American College of Cardiology

MAY 22, 2024

Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.

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Science Daily - Heart Disease

SEPTEMBER 10, 2024

When they become fathers, men who have an unhealthy, high-cholesterol diet can cause increased risk of cardiovascular disease, or CVD, in their daughters, a mouse study has found.

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Medical Xpress - Cardiology

DECEMBER 13, 2023

A recent trial of a novel gene-editing technique that lowered dangerously high cholesterol by up to 55% has generated talk of a new front opening against cardiovascular disease, which kills nearly 700,000 Americans each year and is the nation's leading cause of death.

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The New England Journal of Medicine

AUGUST 30, 2024

Taking a long-term view of cardiovascular disease prevention is an attractive strategy since atherosclerosis begins early in life and progresses over decades. Lowering low-density lipoprotein (LDL) cholesterol levels and improving lifestyle habits are mainstay strategies for reducing the risk of cardiovascular disease.1

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Journal of the American Heart Association

FEBRUARY 29, 2024

The objective of this study was to examine the prospective association between plasma RvD2 and the risk of atherosclerotic cardiovascular disease (ASCVD) at the population level.Methods and ResultsA cohort of 2633 community‐dwelling individuals aged 35–60 years was followed for 8 years in this study. P<0.001).

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Science Daily - Heart Disease

NOVEMBER 13, 2023

Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.

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Journal of the American Heart Association

MARCH 8, 2024

Lowering low‐density lipoprotein cholesterol (LDL‐C) is a cornerstone of reducing risk for atherosclerotic cardiovascular disease. Journal of the American Heart Association, Ahead of Print. Barriers include poor adherence, clinical inertia, concern for side effects, cost, and complex prior authorization processes.

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Cardiovascular Diabetology

OCTOBER 13, 2024

Older general population-based studies found an inverse association between serum HDL-cholesterol and both cardiovascular disease (CVD) events and mortality, but more recent data have suggested a U-shaped rela.

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Science Daily - Heart Disease

FEBRUARY 20, 2024

But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease. The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide.

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Frontiers in Cardiovascular Medicine

NOVEMBER 19, 2024

BackgroundOne measurement of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is considered to be associated with insulin resistance and cardiovascular disease (CVD) risk. This association remained significant even after further adjustment for single measurements of NHHR.

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Dr. Malcolm Kendrick

DECEMBER 5, 2024

In my opinion, or should I say ‘allegedly’ what actually happened here was that Barney Calman had heard from various cardiology experts that cholesterol and statin ‘deniers’ were causing people to stop taking their drugs. As a writer and lecturer, he has a specialist interest in the epidemiology of cardiovascular disease.

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Cardiometabolic Health Congress

JANUARY 15, 2025

Atherosclerosisa key driver of cardiovascular disease (CVD)continues to be a significant global health issue. These cases are particularly challenging because traditional prevention strategies, which target known risks like high LDL cholesterol, hypertension, diabetes, and smoking, may not apply.

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Circulation

NOVEMBER 29, 2023

BACKGROUND:Cholesterol efflux capacity (CEC) predicts cardiovascular disease independently of high-density lipoprotein (HDL) cholesterol levels. Enhanced CEC, as seen with the smaller particles, predicts decreased cardiovascular disease risk. Circulation, Ahead of Print.

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Medical Xpress - Cardiology

FEBRUARY 23, 2024

When people hear about predicting heart disease, most will think of cholesterol levels.

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Journal of Clinical Investigation - Cardiology

MARCH 1, 2024

Patients with chronic inflammatory disorders such as psoriasis have an increased risk of cardiovascular disease and elevated levels of LL37, a cathelicidin host defense peptide that has both antimicrobial and proinflammatory properties.

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JAMA Cardiology

JANUARY 16, 2024

This prespecified analysis of the Cholesterol Lowering via Bempedoic Acid, an ATP Citrate Lyase (ACL)–Inhibiting Regimen (CLEAR) Outcomes trial investigates if bempedoic acid is associated with a reduction in the total burden of cardiovascular events in patients at high risk for cardiovascular disease.

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Med Page Today

AUGUST 31, 2024

(MedPage Today) -- LONDON -- A combination of three factors -- high-sensitivity C-reactive protein (hsCRP), LDL cholesterol, and lipoprotein(a), or lp(a) -- independently predicted cardiovascular disease over 30 years in women who were initially.

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Cholesterol Cardiovascular Disease 93

Medical Xpress - Cardiology

JULY 29, 2024

A recently unveiled cardiovascular disease risk calculator that measures a patient's risk for heart attack and stroke is better calibrated and more precise than its previous version, but if current treatment guidelines for cholesterol and blood pressure therapy remain unchanged, the new calculator may have unintended consequences, according to research (..)

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Science Daily - Heart Disease

FEBRUARY 19, 2024

Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease.

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Cardiovascular Diabetology

JANUARY 7, 2025

Remnant cholesterol (remnant-C) contributes to atherosclerotic cardiovascular disease (ASCVD), particularly in individuals with impaired glucose metabolism. Patients with impaired glu.

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Heart 2023 Conference

MAY 9, 2022

Despite this, including them to a person’s food regimen can assist raise “suitable” ldl cholesterol degrees. However, they'll now no longer assist decrease “awful” ldl cholesterol with out extra food regimen changes. Some declare it could additionally decrease low-density lipoprotein (LDL) ldl cholesterol, called awful ldl cholesterol.

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