Circulation: Genomic and Precision Medicine

DECEMBER 7, 2023

BACKGROUND:Few clinical data are available onNEXNmutation carriers, and the gene’s involvement in cardiomyopathies or sudden death has not been fully established. years), 21 presented with dilated cardiomyopathy (prevalence, 0.33%), and 3 presented with hypertrophic cardiomyopathy (prevalence, 0.14%).

Sudden Cardiac Death 40

Sudden Cardiac Death Cardiomyopathy Circulation 40

American College of Cardiology

MAY 2, 2024

What is the prognostic value of extent of late gadolinium enhancement (LGE) in predicting sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM)?

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Sudden Cardiac Death Cardiomyopathy Article 64

Circulation: Genomic and Precision Medicine

FEBRUARY 28, 2024

Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death. Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiomyopathy 72

Cardiomyopathy Sudden Cardiac Death Article Heart Failure 72

HeartRhythm

MAY 7, 2024

Implantable cardioverter defibrillator (ICD) prevents sudden cardiac death (SCD) in patients with ischemic cardiomyopathy (ICM). Catheter ablation has been shown to effectively reduce ventricular tachycardia (VT) recurrence, yet its efficacy in patients without an ICD implantation remains uncertain.

Sudden Cardiac Death 45

Sudden Cardiac Death Tachycardia Cardiomyopathy Ablation 45

HeartRhythm

DECEMBER 31, 2023

There has been a recent surge of interest in efforts to refine the risk stratification for sudden cardiac death (SCD) in children and adolescents with hypertrophic cardiomyopathy (HCM).

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Pediatrics 40

HeartRhythm

OCTOBER 27, 2024

Sudden cardiac death (SCD) remains a major health problem in all continents. It usually affects older patients suffering from coronary artery disease and cardiomyopathies. This group of patients defines the sudden arrhythmic death syndrome (SADS) where the cause of death is unknown.

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Sudden Cardiac Death Coronary Artery Disease Cardiac Arrest Cardiomyopathy 73

Frontiers in Cardiovascular Medicine

JULY 11, 2024

BackgroundDilated cardiomyopathy (DCM) is a heterogeneous myocardial disorder with diverse genetic or acquired origins. Notable advances have been achieved in discovering and understanding the genetics of DCM.

Cardiomyopathy 52

Cardiomyopathy Research Sudden Cardiac Death Document 52

Heart BMJ

JUNE 25, 2024

Hypertrophic cardiomyopathy (HCM) stands as one of the most common inheritable myocardial disease and is often marked by its association with sudden cardiac death (SCD) in the young. 1 2 Traditionally, risk assessment in HCM has focused mainly on estimating the likelihood of SCD.

Cardiomyopathy 52

Cardiomyopathy Sudden Cardiac Death Atrial Fibrillation Risk Factors 52

HeartRhythm

APRIL 30, 2024

Predictive factors of benefit from implantation of an implantable cardioverter-defibrillator (ICD) for primary prophylaxis of sudden cardiac death in patients with nonischemic cardiomyopathy (NICM) have not been clarified.

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Sudden Cardiac Death Cardiomyopathy Defibrillator 40

HeartRhythm

APRIL 30, 2024

Hypertrophic cardiomyopathy (HCM) is associated with risk of sudden cardiac death (SCD). Since approval in late 2012, the subcutaneous implantable cardioverter-defibrillator (SICD) has been used as an alternative to the traditional transvenous ICD (TV-ICD) for SCD prevention in HCM.

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Defibrillator Sudden Cardiac Death Cardiomyopathy 40

Frontiers in Cardiovascular Medicine

MARCH 13, 2024

Peripartum Cardiomyopathy (PPCM) is a polymorphic myocardial disease occurring late during pregnancy or early after delivery. The issue is relevant since some arrhythmias are associated to sudden cardiac death occurring in young patients, and the overall risk does not cease during the early postpartum period.

Cardiomyopathy 59

Cardiomyopathy Sudden Cardiac Death Outpatient Arrhythmia 59

HeartRhythm

NOVEMBER 27, 2023

Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease characterized by replacement of ventricular myocardial by fibrofatty scar tissue which underlies morpho-functional ventricular abnormalities and life-threatening ventricular arrhythmias potentially responsible of sudden cardiac death (SCD), mostly in young people and athletes 1,2.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Arrhythmia 40

American College of Cardiology

OCTOBER 2, 2024

What is the association between late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (cMRI) and sudden cardiac death (SCD) in pediatric patients with hypertrophic cardiomyopathy (HCM), and does it add to pediatric SCD risk models?

Sudden Cardiac Death 48

Sudden Cardiac Death Pediatrics Cardiomyopathy Article 48

HeartRhythm

APRIL 30, 2024

Frequent premature ventricular contractions (PVCs) are linked to development of cardiomyopathy (CM) characterized by reduced LV ejection fraction and increased risk of sudden cardiac death. PVC-CM is thought to be triggered by elevated mechanical myocardial strain due to dyssynchronous contraction during PVCs.

Sudden Cardiac Death 40

Sudden Cardiac Death Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

Hypertrophic cardiomyopathy (HCM) is associated with risk of sudden cardiac death (SCD). Since approval in late 2012, the subcutaneous implantable cardioverter-defibrillator (SICD) has been used as an alternative to the traditional transvenous ICD (TV-ICD) for SCD prevention in HCM.

Defibrillator 40

Defibrillator Sudden Cardiac Death Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

Hypertrophic cardiomyopathy (HCM) has a prevalence of 1 in 500 people and highly increases the risk of sudden cardiac death (SCD). Diagnosis is typically based on the Echocardiogram, while cardiac MRI is used for detection of myocardial scarring through Late Gadolinium Enhancement (LGE), an important risk marker for SCD.

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Sudden Cardiac Death Cardiomyopathy Electrocardiogram Echocardiogram 40

HeartRhythm

SEPTEMBER 14, 2023

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic cardiomyopathy resulting from disordered function of the intercalated discs with mainly arrhythmic manifestation, which can be difficult to diagnose because of its variable presentation. The incidence of ARVC is reported to be 1:2000 to 1:5000.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Arrhythmia 40

HeartRhythm

FEBRUARY 13, 2024

Hypertrophic cardiomyopathy (HCM) is the leading cause of sudden cardiac death (SCD) in youth. Cardiac; magnetic resonance imaging (CMR) has been invaluable in improving the risk stratification of these patients for SCD1.

Sudden Cardiac Death 40

Sudden Cardiac Death Cardiomyopathy 40

HeartRhythm

OCTOBER 19, 2023

Hypertrophic cardiomyopathy (HCM)-related sudden cardiac death (SCD) rates with contemporary management are low; however, high-intensity exercise can induce fatal arrhythmias in HCM patients. Thus, current guidelines recommend avoiding high-intensity exercise in HCM patients at high risk for SCD1,2.

Exercise 40

Exercise Cardiomyopathy Sudden Cardiac Death Cardiovascular Disease 40

European Journal of Heart Failure

FEBRUARY 26, 2024

Dilated cardiomyopathy with arrhythmic phenotype. Abstract Aims Dilated cardiomyopathy (DCM) with arrhythmic phenotype combines phenotypical aspects of DCM and predisposition to ventricular arrhythmias, typical of arrhythmogenic cardiomyopathy.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Arrhythmia Tachycardia 40

European Journal of Heart Failure

SEPTEMBER 24, 2023

Abstract Cardiomyopathies represent significant contributors to cardiovascular morbidity and mortality. Furthermore, medications targeting core disease processes and/or their downstream adverse effects have been introduced for several cardiomyopathies.

Document 40

Document Cardiomyopathy Sudden Cardiac Death Heart Failure 40

Circulation

NOVEMBER 11, 2024

Introduction:We present a case of hypertrophic obstructive cardiomyopathy (HOCM) with incidental wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) discovered after septal myectomy.Case presentation:A 62-year-old male with a history of bilateral carpal tunnel syndrome as well as a family history of sudden cardiac death consistent with HOCM on (..)

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Echocardiogram Bicuspid/Mitral 40

Circulation: Cardiovascular Quality & Outcomes

JANUARY 19, 2024

Background:Serum troponins and CK-MB (creatine kinase-MB) are readily detectable and reliable cardiac-specific biomarkers of subclinical myocardial injury. This study explores the roles of cTnI (cardiac troponin I) and CK-MB in hypertrophic cardiomyopathy (HCM).Methods:This Higher cTnI (per 0.05

Biomarkers 40

Biomarkers Sudden Cardiac Death Coronary Artery Bypass Graft Cardiomyopathy 40

Heart BMJ

JANUARY 10, 2024

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disease characterised by fibrofatty replacement of the ventricular myocardium due to specific mutations, leading to ventricular arrhythmias and sudden cardiac death.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Ablation Arrhythmia 40

Open Heart

APRIL 20, 2022

Objectives To describe a cohort of patients with arrhythmogenic left ventricular cardiomyopathy (ALVC), focusing on the spectrum of the clinical presentations. Twenty-one (41%) had normal echocardiogram, 13 (25%) a hypokinetic non-dilated cardiomyopathy (HNDC) and 17 (33%) a dilated cardiomyopathy (DCM).

Cardiomyopathy 52

Cardiomyopathy Chest Pain Sudden Cardiac Death Heart Failure 52

The American Journal of Cardiology

APRIL 19, 2024

Publication date: Available online 18 April 2024 Source: The American Journal of Cardiology Author(s): Xinyu Zhu, Yuan Tian, Ying Shi, Jianxiu Lian, Honghu Shen, Lulu Li, Haishan Wu, Pengfei Liu

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Sudden Cardiac Death Risk Factors Cardiomyopathy 40

DAIC

APRIL 9, 2024

Maron, MD , a cardiologist and director of the Hypertrophic Cardiomyopathy Center at Lahey Hospital and Medical Center in Burlington, Massachusetts, and the study’s lead author. It causes the heart muscle to become stiff and thick, making it harder for the heart to pump blood properly and increasing the risk of sudden cardiac death.

Cardiomyopathy 52

Cardiomyopathy Quality of Life Preserved Ejection Fraction Chest Pain 52

Circulation

NOVEMBER 11, 2024

It presents in acute, indeterminate, and chronic phases, with chronic cardiomyopathy being the most severe form, leading to heart failure, arrhythmias, and sudden cardiac death. Introduction:Chagas disease is a significant cause of tropical disease-related mortality.

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Sudden Cardiac Death Cardiomyopathy Heart Failure Arrhythmia 40

American College of Cardiology

DECEMBER 12, 2023

How does the 2022 European Society of Cardiology (ESC) risk model for sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) perform compared with risk models from previous guidelines? And does late gadolinium enhancement (LGE) further improve SCD risk stratification?

Sudden Cardiac Death 44

Sudden Cardiac Death Cardiomyopathy Article 44

HeartRhythm

APRIL 30, 2024

There is an unmet need for better risk stratification for sudden cardiac death in the era of primary prevention ICD therapy. Scar burden on LGE-CMR imaging may be a risk marker for ventricular arrhythmia post-myocardial infarction (MI).

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Sudden Cardiac Death Risk Factors Myocardial Infarction Cardiomyopathy 40

DAIC

MAY 9, 2024

The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). Ommen, MD, FACC , medical director of the Mayo Hypertrophic Cardiomyopathy Clinic and chair of the guideline writing committee.

Cardiomyopathy 52

Cardiomyopathy Pediatrics Quality of Life Sudden Cardiac Death 52

HeartRhythm

JUNE 3, 2024

Most patients with VT and structural heart disease preparing for ablation either have or are about to receive an implantable cardioverter defibrillator (ICD) shortly after the procedure to prevent sudden cardiac death from recurrent ventricular arrhythmias (VA).

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Sudden Cardiac Death Tachycardia Ablation Defibrillator 40

Circulation: Genomic and Precision Medicine

NOVEMBER 28, 2023

BACKGROUND:Hypertrophic cardiomyopathy (HCM) is an important cause of sudden cardiac death associated with heterogeneous phenotypes, but there is no systematic framework for classifying morphology or assessing associated risks. Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Hypertension Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142952-A4142952, November 12, 2024.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Defibrillator Risk Factors 40

Circulation

NOVEMBER 11, 2024

Since its identification in 1981 its diagnosis has increased due to the advancements in cardiac imaging. It’s association with ventricular arrythmia (VA) and sudden cardiac death (SCD) underscores the importance of its identification. Electrocardiogram (ECG) showed sustained monomorphic VT at a rate of 160 bpm.

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Bicuspid/Mitral Aneurysm Sudden Cardiac Death Tachycardia 40

HeartRhythm

APRIL 30, 2024

Current clinical guidelines fall short in accurately identifying HCM patients at risk for sudden cardiac death due to VA.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia Risk Factors Cardiomyopathy 40

DAIC

FEBRUARY 22, 2024

Researchers Elizabeth Jordan and Ray Hershberger, MD discuss the results of genetic tests that indicate a risk for dilated cardiomyopathy. Dilated cardiomyopathy can be a silent killer DCM is a condition in which the heart muscle weakens and the left ventricle enlarges. The Dilated Cardiomyopathy Consortium was funded by a $12.4

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Heart Failure Sudden Cardiac Death Heart Transplant Cardiomyopathy 104