European Journal of Heart Failure

DECEMBER 7, 2023

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). As the severity of obesity increased, symptoms (Kansas City Cardiomyopathy Questionnaire score) and 6-min walk distance worsened.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Obesity Heart Failure BMI 40

American College of Cardiology

JUNE 24, 2024

Semaglutide reduces body weight to a greater extent in women with obesity-related heart failure with preserved ejection fraction (HFpEF) than in men, and improved Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) to the same extent in both women and men, according to results from a prespecified secondary analysis of pooled (..)

Preserved Ejection Fraction 59

Preserved Ejection Fraction Obesity Heart Failure Cardiomyopathy 59

Cardiovascular Diabetology

OCTOBER 18, 2024

Type 2 diabetes mellitus (T2DM) is a major risk factor for heart failure with preserved ejection fraction and cardiac arrhythmias. Precursors of these complications, such as diabetic cardiomyopathy, remain inc.

Preserved Ejection Fraction 52

Preserved Ejection Fraction Diabetes Heart Failure Risk Factors 52

JAMA Cardiology

SEPTEMBER 30, 2022

This retrospective cohort study attempts to derive and validate a simple transthyretin amyloid cardiomyopathy score to predict increased risk of transthyretin amyloid cardiomyopathy in patients with heart failure and preserved ejection fraction.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Cardiomyopathy Heart Failure 40

HeartRhythm

APRIL 30, 2024

Little is known about pacing-induced cardiomyopathy (PICM) in patients with preserved ejection fraction (EF).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Pacemaker Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

The incidence of pacemaker mediated cardiomyopathy (PMC) by right ventricular (RV) pacing has been estimated at 10% to 20%. Left bundle brunch area (LBBA) pacing may result in a lower risk for the of development of PMC.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Pacemaker Cardiomyopathy 40

Frontiers in Cardiovascular Medicine

FEBRUARY 11, 2024

ATTRwt was previously known as “senile amyloidosis” and causes cardiomyopathy which may lead to heart failure with a preserved ejection fraction, affecting predominantly elderly men. The exact prevalence of ATTRwt in the general population remains unclear, but its occurrence may be underestimated in women.

Preserved Ejection Fraction 59

Preserved Ejection Fraction Cardiomyopathy Document Heart Failure 59

HeartRhythm

SEPTEMBER 4, 2024

Transthyretin cardiac amyloidosis (ATTR-CA) is the most common type of amyloid cardiomyopathy which frequently presents with cardiac arrythmias. However, the impact of SGLT2i on cardiovascular outcomes in patients with established cardiac arrythmias and ATTR-CA has not yet been evaluated.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Outcomes Heart Failure Cardiomyopathy 40

Circulation: Heart Failure

DECEMBER 18, 2023

RESULTS:In hypertrophic cardiomyopathy, RT (estimated marginal mean [95% CI]) was 3.4 (0.4–6.4) mm Hg in HF with preserved ejection fraction patients and was also exacerbated by exercise. mm Hg, increasing to 18.5 mm Hg with exercise (P<0.001). In controls, RT was 0.0 mm Hg and 1.2 (0.3–2.8)

Preserved Ejection Fraction 40

Preserved Ejection Fraction Exercise Cardiomyopathy Heart Failure 40

Circulation

NOVEMBER 11, 2024

Introduction:Mavacamten is a cardiac myosin inhibitor that has been approved for obstructive hypertrophic cardiomyopathy (oHCM). The CardioMEMS PA (pulmonary artery) sensor allows remote pulmonary artery diastolic (PAD) pressure monitoring to adjust diuresis in heart failure with preserved ejection fraction (HFpEF).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Cardiomyopathy Heart Failure Pulmonary 40

Frontiers in Cardiovascular Medicine

OCTOBER 10, 2024

Patients diagnosed with reduced ejection fraction (HFrEF) and with heart failure with mildly reduced ejection fraction (HFmrEF) were treated with Vericiguat combined with “ARNI, BB, MRA, SGLT2i” therapy. vs. 43.1 ± 8.5%, P < 0.01), LVEDD (60.5 ± 8.1 vs. 58.2 ± 7.3 mm, mm, P < 0.01), NT-proBNP (4,567.8 ± 5,163.9

Heart Failure 52

Heart Failure Preserved Ejection Fraction Cardiac Function Quality of Life 52

Journal of Cardiovascular Electrophysiology

DECEMBER 15, 2023

Impact of preceding systolic heart failure on risk of pacemaker-induced cardiomyopathy Abstract Background Pacemaker-induced cardiomyopathy is a well described phenomenon in patients with preserved ejection fraction at the time of permanent pacemaker implant.

Heart Failure 40

Heart Failure Preserved Ejection Fraction Pacemaker Cardiomyopathy 40

DAIC

FEBRUARY 29, 2024

12:15 p.m.

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

European Journal of Heart Failure

APRIL 13, 2025

The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status. Of the 6001 patients randomized in FINEARTS-HF, 773 patients (12.9%) had COPD.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Pulmonary Peripheral Arterial Disease 40

DAIC

MARCH 25, 2025

25 include Efficacy and safety of finerenone across the spectrum of kidney risk in heart failure with mildly reduced or preserved ejection fraction during the session;"Innovations and Insights in Heart Failure With Preserved Ejection Fraction: Emerging Therapies, Biomarkers and Mechanistic Studies."

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Kidney Disease Research 52

European Journal of Heart Failure

DECEMBER 13, 2023

BMI, body mass index; CI, confidence interval; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. ABSTRACT Aim Chronic obstructive pulmonary disease (COPD) is common in heart failure with a mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and is associated with worse outcomes.

Preserved Ejection Fraction 75

Preserved Ejection Fraction Heart Failure Pulmonary Quality of Life 75

Circulation

DECEMBER 7, 2023

In the 504 patients with HF with preserved ejection fraction, the median placebo-corrected 16-week difference in KCCQ-TSS and KCCQ-PLS was 3.2 (95% P=0.50) for 6MWD.CONCLUSIONS:Dapagliflozin improved the KCCQ-TSS in patients with HF with reduced ejection fraction but did not improve KCCQ-PLS or 6MWD. 95% CI, 0.4,

Preserved Ejection Fraction 84

Preserved Ejection Fraction Heart Failure Exercise Cardiomyopathy 84

DAIC

MARCH 25, 2025

25 include Efficacy and safety of finerenone across the spectrum of kidney risk in heart failure with mildly reduced or preserved ejection fraction during the session;"Innovations and Insights in Heart Failure With Preserved Ejection Fraction: Emerging Therapies, Biomarkers and Mechanistic Studies."

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Research Academic 52

European Journal of Heart Failure

APRIL 10, 2025

Finerenone and glycaemic status in patients with heart failure with mildly reduced/preserved ejection fraction. CI, confidence interval; CV, cardiovascular; HF, heart failure; HR, hazard ratio; RR, rate ratio.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Diabetes Cardiomyopathy 40

Circulation

NOVEMBER 17, 2024

Background: Patients with heart failure, a preserved ejection fraction (HFpEF), and obesity have significant disability and suffer frequent exacerbations of heart failure. Circulation, Ahead of Print. n=393) were female; BMI 38.26.7kg/m2, KCCQ-CSS 53.518.5,

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Obesity Quality of Life 40

DAIC

APRIL 9, 2024

Maron, MD , a cardiologist and director of the Hypertrophic Cardiomyopathy Center at Lahey Hospital and Medical Center in Burlington, Massachusetts, and the study’s lead author. For more information on hypertrophic cardiomyopathy, visit CardioSmart.org/HCM. The safety and tolerability of the drug in this phase 2 trial was excellent.

Cardiomyopathy 52

Cardiomyopathy Quality of Life Chest Pain Preserved Ejection Fraction 52

Circulation

NOVEMBER 11, 2023

Background:Patients with heart failure (HF) with preserved ejection fraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. Circulation, Ahead of Print. In the STEP-HFpEF trial, once-weekly semaglutide 2.4 In the STEP-HFpEF trial, once-weekly semaglutide 2.4

Preserved Ejection Fraction 40

Preserved Ejection Fraction Quality of Life Obesity Heart Failure 40

International Journal of Cardiovascular Sciences

OCTOBER 21, 2024

Santos Most Cited Article – Reduction in Hospitalization and Increase in Mortality Due to Cardiovascular Diseases during the COVID-19 Pandemic in Brazil Authors: Paulo Garcia Normando, José de Arimatéia Araujo-Filho, Gabriela de Alcântara Fonseca, Rodrigo Elton Ferreira Rodrigues, Victor Agripino Oliveira, Ludhmila Abrahão Hajjar, André Luiz (..)

Article 52

Article Preserved Ejection Fraction COVID-19 Heart Failure 52

DAIC

APRIL 6, 2024

The trial, called RELIEVE-HF , is the first randomized placebo-procedure controlled trial of interatrial shunting that included patients with both major types of heart failure : heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).

Heart Failure 81

Heart Failure Quality of Life Outcomes Preserved Ejection Fraction 81

DAIC

APRIL 6, 2024

The trial, called RELIEVE-HF , is the first randomized placebo-procedure controlled trial of interatrial shunting that included patients with both major types of heart failure : heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).

Heart Failure 75

Heart Failure Quality of Life Preserved Ejection Fraction Hospital 75

Dr. Smith's ECG Blog

OCTOBER 28, 2023

LVH is a common etiology of heart failure with preserved ejection fraction, as it may results in a stiff ventricle with poor diastolic relaxation. LVH can have very thick-walled ventricles and a correspondingly small LV cavity. We gave him IV fluids and metoprolol, and his pulse normalized, after which he felt completely well.

Preserved Ejection Fraction 57

Preserved Ejection Fraction Sudden Cardiac Death Chest Pain Heart Failure 57

Cardiology Update

APRIL 9, 2024

STEP-HFpEF DM 5 ( NCT04916470 ) explored the effects of semaglutide in obesity-related HF with preserved ejection fraction (HFpEF) and type 2 diabetes. Patients receiving semaglutide showed a greater change in Kansas City Cardiomyopathy Questionnaire (KCCQ) clinical summary scores at 52 weeks than placebo.

Angina 52

Angina Myocardial Infarction Aortic valve Coronary Artery Disease 52

Journal of the American Heart Association

MARCH 13, 2025

The risk of allcause and noncardiovascular mortality and first allcause hospitalization was higher with EF values &gt;55% in crude but not adjusted analyses.ConclusionsAmong patients with HF with preserved EF, 21% had EF 60%.

Preserved Ejection Fraction 70

Preserved Ejection Fraction Heart Failure Peripheral Arterial Disease Cardiomyopathy 70

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2025

BackgroundThe mortality of patients with acute myocardial infarction (MI) raised rapidly in last decade and obesity are becoming the major cause to CAD progression, thus inducing heart failure preserved ejection fraction (HFpEF). Nine hub genes were obtained, including OGN, SELL, FOS, NKG7, LOX, HBB, CXCL9, CP and ALOX5.

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Myocardial Infarction Download 52