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The Role of Genetics in Heart Disease: Can You Prevent It?

MIBHS

Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries. Cardiomyopathies: These diseases affect the heart muscle, impairing its ability to pump blood effectively.

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What is Takotsubo Cardiomyopathy (Broken Heart Syndrome)?

BoardVitals - Cardiovascular

Because it’s the month that houses Valentine’s Day, it is obviously the most appropriate month to share information about takotsubo cardiomyopathy. Takotsubo cardiomyopathy is commonly known by a few other names as well – stress cardiomyopathy, apical ballooning syndrome, broken heart syndrome, and stress-induced cardiomyopathy.

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What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

Dr. Smith's ECG Blog

Angiogram No obstructive epicardial coronary artery disease Cannot exclude non-ACS causes of troponin elevation including coronary vasospasm, stress cardiomyopathy, microvascular disease, etc. We know that most type 1 acute MI due to plaque rupture and thrombosis occurs in lesions that are less than 50% (see Libby reference).

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Understanding an Enlarged Heart (Cardiomegaly): Causes, Symptoms, and Treatment

MIBHS

Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart. Cardiomyopathy Cardiomyopathy is a condition that affects the heart muscle, causing it to become enlarged, thick, or rigid.

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ECG Blog #415 — The Cath showed NO Occlusion!

Ken Grauer, MD

Non-obstructive coronary disease at the time cardiac cath is done does not necessarily imply there was no plaque rupture with thrombus. These plaques will often not be recognized as "culprits" — because no fissuring or ulceration is seen. Longterm prognosis of patients with MINOCA clearly depends on the underlying etiology.

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Concerning EKG with a Non-obstructive angiogram. What happened?

Dr. Smith's ECG Blog

The commonest causes of MINOCA include: atherosclerotic causes such as plaque rupture or erosion with spontaneous thrombolysis, and non-atherosclerotic causes such as coronary vasospasm (sometimes called variant angina or Prinzmetal's angina), coronary embolism or thrombosis, possibly microvascular dysfunction. It is not rare.

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"A patient just arrived as a transfer for NSTEMI."

Dr. Smith's ECG Blog

Given her lack of risk factors for coronary disease, and the fact that she was a 53 year old woman with compatible history and echo findings, stress cardiomyopathy rose to the top of my differential. Of course, stress cardiomyopathy is a diagnosis of exclusion. But not all OMI is atherosclerotic in nature.

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