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Background Heart failure (HF) is a serious and common condition affecting millions of people worldwide, with obesity being a major cause of metabolic disorders such as diabetes and cardiovascular disease. Conclusions The findings suggest that fenofibrate may be a useful therapeutic agent for obesity- and diabetes-related cardiomyopathy.
Case presentation A 43-year-old man with a body mass index of 41 kg/m 2 was admitted to our hospital for acute heart failure due to dilated cardiomyopathy. We initiated a mobilization program, but the patient's mobility was highly limited due to severe obesity and symptomatic orthostatic hypotension.
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Semaglutide reduces body weight to a greater extent in women with obesity-related heart failure with preserved ejection fraction (HFpEF) than in men, and improved Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) to the same extent in both women and men, according to results from a prespecified secondary analysis of pooled (..)
Cardiomyopathy, a heterogeneous pathological condition characterized by changes in cardiac structure or function, represents a significant risk factor for the prevalence and mortality of cardiovascular disease (CVD). Research conducted over the years has led to the modification of definition and classification of cardiomyopathy.
And of course Ken's comments at the bottom) An elderly obese woman with cardiomyopathy, Left bundle branch block, and chronic hypercapnea presented hypoxic with altered mental status. By Smith with comments from our electrophysiologist, Rehan Karim. She was intubated. Bedside cardiac ultrasound showed moderately decreased LV function.
Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. Overall, 60.9%
Introduction:Mavacamten is a cardiac myosin inhibitor that has been approved for obstructive hypertrophic cardiomyopathy (oHCM). Circulation, Volume 150, Issue Suppl_1 , Page A4123391-A4123391, November 12, 2024.
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Between 2016 and 2018, 3285 MESA participants from 6 field centers underwent comprehensive speckle-tracking echocardiography with passive leg raise maneuver, Kansas City Cardiomyopathy Questionnaire, 6-minute walk test, arterial stiffness assessment, and proteomics (including NT-proBNP [N-terminal pro-B-type natriuretic peptide]).Results:Median
A 35-year-old gravida 1, para 0 with biventricular heart failure (LVEF 25%), nonischemic cardiomyopathy, history stroke, history of left ventricular thrombus, class III obesity, and chronic kidney disease who had been followed by Cardio-Obstetrics throughout her pregnancy presented at 34 weeks gestation for planned induction of labor.
Cardiomyopathies: These diseases affect the heart muscle, impairing its ability to pump blood effectively. Mutations in specific genes often cause hypertrophic cardiomyopathy and dilated cardiomyopathy. Medication and Medical Interventions Sometimes, lifestyle changes alone may not be enough to counteract genetic risks.
Background We aimed to clarify the existence and pathological features of obesitycardiomyopathy (OCM) in Japan using our series of autopsy cases. We compared cases of OCM with those with obesity without cardiac hypertrophy (OB) and normal weight without cardiac hypertrophy (normal control).
Heavy and repeated binge drinking can lead to alcoholic cardiomyopathy, a condition in which the heart muscle weakens and struggles to pump blood efficiently. Additionally, alcohol contributes to weight gain, as many alcoholic beverages are high in empty calories, leading to an increased risk of obesity and its associated heart complications.
Background:Patients with heart failure (HF) with preserved ejection fraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. Circulation, Ahead of Print. In the STEP-HFpEF trial, once-weekly semaglutide 2.4 In the STEP-HFpEF trial, once-weekly semaglutide 2.4
Background: Patients with heart failure, a preserved ejection fraction (HFpEF), and obesity have significant disability and suffer frequent exacerbations of heart failure. Circulation, Ahead of Print. n=393) were female; BMI 38.26.7kg/m2, KCCQ-CSS 53.518.5,
We aimed to investigate the safety of intravenous tissue plasminogen activator (IV tPA) and mechanical thrombectomy (MT) for acute ischemic stroke (AIS), and compare the functional outcome in cardiomyopathy patients with and without HF. 37.6%, p < 0.001), obesity (9.2% 24.2%, p < 0.001), diabetes mellitus (39.7%
Updated Mayo Clinic HCM Genotype Predictor Score: Iuri Ferreira Felix, MD (USA) presented the updated Mayo Clinic HCM Genotype Predictor Score, a valuable screening tool for identifying hypertrophic cardiomyopathy (HCM) patients with a high likelihood of testing positive for genetic mutations.
She is one of the first fellowship-trained obesity medicine physicians in the world. Anuradha Lala-Trindade, MD: She focuses on the selection and care of patients with mechanical circulatory support devices and heart transplantation, genetic cardiomyopathies, and perioperative management of high-risk cardiac surgical cases.
STEP-HFpEF DM 5 ( NCT04916470 ) explored the effects of semaglutide in obesity-related HF with preserved ejection fraction (HFpEF) and type 2 diabetes. Investigators randomized 616 adult patients with HFpEF and obesity to receive either once weekly semaglutide (n=310) or placebo (n=306).
Institutional Coronary Artery Bypass Case Volumes and Outcomes European Journal of Heart Failure October 2023 Makoto Mori Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation The Annals of Thoracic Surgery August 2023 Carlos Diaz-Castrillion Volume-Failure to Rescue Relationship in Acute Type A Aortic Dissections: An Analysis of The Society (..)
Institutional Coronary Artery Bypass Case Volumes and Outcomes European Journal of Heart Failure October 2023 Makoto Mori 1 Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation The Annals of Thoracic Surgery August 2023 Carlos Diaz-Castrillion 2 Volume-Failure to Rescue Relationship in Acute Type A Aortic Dissections: An Analysis of The (..)
SUMMIT Trial : Weekly subcutaneous tirzepatide showed significant reductions in CV death and HF-related events among patients with HFpEF and obesity. VANISH2 Trial : Catheter ablation as first-line therapy reduced VT episodes more effectively than antiarrhythmic drugs in ischemic cardiomyopathy patients. Access the full study.
BackgroundThe mortality of patients with acute myocardial infarction (MI) raised rapidly in last decade and obesity are becoming the major cause to CAD progression, thus inducing heart failure preserved ejection fraction (HFpEF). Nine hub genes were obtained, including OGN, SELL, FOS, NKG7, LOX, HBB, CXCL9, CP and ALOX5.
November 2024 Approvals Acoramidis Approval Date: November 22, 2024 Indication: Approved for adults with transthyretin amyloid cardiomyopathy (ATTR-CM), a rare and severe cardiac condition.
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