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The New England Journal of Medicine
OCTOBER 30, 2024
A 69-year-old man with a history of MI and cardiomyopathy presented with 2 days of dyspnea. Regular tachycardia (124 beats per min), diaphoresis, and rales were present. A diagnosis was made.
Circulation: Cardiovascular Imaging
OCTOBER 2, 2024
Circulation: Cardiovascular Imaging, Ahead of Print.
Frontiers in Cardiovascular Medicine
DECEMBER 13, 2023
In this review, we comprehensively review the regulation mechanism of SFⅡ helicases in CVDs including atherosclerosis, myocardial infarction, cardiomyopathies, and heart failure, which will contribute to the investigation of ideal therapeutic targets for CVDs.
EMS 12-Lead
MAY 20, 2022
She reports a known history of Hypertrophic Cardiomyopathy (HCM) with left ventricular outflow tract obstruction and is on daily beta blocker therapy. Diagnosis and management of hypertrophic cardiomyopathy: Expert analysis. Chapter 10: Hypertrophic Cardiomyopathy (pg. References Naidu, S. American College of Cardiology.
DAIC
FEBRUARY 29, 2024
12:15 p.m.
103 
All About Cardiovascular System and Disorders
APRIL 30, 2024
Hypertrophic cardiomyopathy is a genetic disorder with a guarded prognosis which occurs in about 1:500 individuals. The most common symptom of hypertrophic cardiomyopathy is dyspnoea which occurs in 90% of cases and is due to elevated left ventricular diastolic pressures as a consequence of the diastolic dysfunction.
Dr. Smith's ECG Blog
NOVEMBER 15, 2023
Angiogram No obstructive epicardial coronary artery disease Cannot exclude non-ACS causes of troponin elevation including coronary vasospasm, stress cardiomyopathy, microvascular disease, etc. Medical Therapy for Secondary Prevention and Long-Term Outcome in Patients With Myocardial Infarction With Nonobstructive Coronary Artery Disease.
Frontiers in Cardiovascular Medicine
OCTOBER 10, 2024
The intergroup comparison showed the therapeutic effect of the combination was equivalent in HF caused by myocardial Infarction (MI), dilated cardiomyopathy (DCM) or Valvular Heart Disease (VHD).ConclusionVericiguat and improved patients’ quality of life scores.
Dr. Smith's ECG Blog
OCTOBER 30, 2023
This is without any intervening infarction. He has "ischemic cardiomyopathy" and "congestive heart failure." In the present STEMI/NSTEMI paradigm, these 2 greatly different (heterogeneous) infarcts are lumped together as one kind of infarct! And this is after undergoing very rapid intervention.
122 
Cardiology Update
JUNE 24, 2024
This comprehensive approach allows for precise differentiation between various cardiomyopathies, myocarditis, and myocardial infarction. Hundley describes that CMR has become a “one-stop shop” for evaluating cardiovascular morphology, perfusion, function, and tissue characterization in a single examination.
Journal of Clinical Investigation - Cardiology
APRIL 1, 2025
Protein aggregates are emerging therapeutic targets in rare monogenic causes of cardiomyopathy and amyloid heart disease, but their role in more prevalent heart-failure syndromes remains mechanistically unexamined. 25-Hydroxycholesterol attenuated CRYAB serine 59 phosphorylation and rescued postmyocardial infarction adverse remodeling.
Dr. Smith's ECG Blog
NOVEMBER 30, 2022
by making it clear to everyone that this is NOT an EKG that one sees with takotsubo cardiomyopathy. Hospital Course The patient was taken emergently to the cath lab which did not reveal any significant coronary artery disease, but she was noted to have reduced EF consistent with Takotsubo cardiomyopathy. It can only be seen by IVUS.
52 
Circulation
OCTOBER 19, 2023
This study aimed to assess the association between PVC burdens during submaximal exercise and major adverse cardiovascular events (MI/HF/LTVA: myocardial infarction [MI], heart failure [HF], and life-threatening ventricular arrhythmia [LTVA]), and all-cause mortality.
40 
Dr. Smith's ECG Blog
APRIL 25, 2023
See our publication: ST depression in lead aVL differentiates inferior ST-elevation myocardial infarction from pericarditis There is STE in inferior leads, high lateral leads, and V4-V6. When there is ST depression (as in aVL, V2, V3), then top on the differential is OMI or myocarditis.
52 
Dr. Smith's ECG Blog
JANUARY 31, 2020
So this is indeed diagnostic of myocardial infarction. Not immediately, at least, because this is NOT diagnostic of ACUTE (occlusion) myocardial infarction (Acute OMI). So I made an ED diagnosis of Non-Occlusion Myocardial Infarction (NOMI), and his next day angiogram confirmed NOMI.
52 
Dr. Sanjay Gupta
DECEMBER 19, 2022
The term MINOCA stands for Myocardial infarction with non-obstructive coronary arteries. Then I think it is important that patient has an assessment of the function of the heart by means of an ultrasound to look for cardiomyopathies, Takotsubo etc. I’ll try and explain this a bit better by using a case study.
Dr. Smith's ECG Blog
JULY 31, 2018
This is diagnostic of myocardial infarction. Troponins may be negative with very rapid reperfusion, or measured too late, or chronically elevated due to cardiomyopathy or renal failure. She felt more comfortable being admitted. Subsequent events: Later, before being taken to her room, the 2nd troponin returned at 1.01
52 
Dr. Smith's ECG Blog
AUGUST 13, 2020
Alternatively , it is someone who has an old myocardial infarction and is now very sick with something else. He had a h/o ischemic cardiomyopathy and right MCA stroke. Below is my response. There is sinus tach. There is an incomplete RBBB and LAFB. There are QR-waves in aVL and V2, and a QS-wave in V3.
52 
Dr. Smith's ECG Blog
MAY 19, 2022
The important point for our purposes is that they do no represent myocardial infarction. Hypertrophic Cardiomyopathy or Normal ("Variant")? Dr. Smith note: I wouldn't necessarily consider this ENTIRELY "benign." It may even be that patients with ECGs with this morphology have a higher long term risk.
52 
All About Cardiovascular System and Disorders
APRIL 14, 2024
A triphasic left ventricular filling pattern with an additional mid diastolic wave, called T wave by some authors and L wave by others, can occur in situations of left ventricular diastolic dysfunction, especially in hypertrophic cardiomyopathy. Another video on this channel describes triphasic mitral flow in more detail. Møller JE et al.
EMS 12-Lead
APRIL 2, 2022
He reported a history of ischemic cardiomyopathy with coronary stent placement approximately 10 years prior, but could not recall the specific artery involved. Terminal QRS distortion is present in anterior myocardial infarction but absent in early repolarization. Attached is the first ECG. 3] Smith, S. 4] Baranchuk, A, et al.
Dr. Smith's ECG Blog
APRIL 17, 2023
Next trop 85,528 ng/L (consistent with a massive myocardial infarction), none further measured. LCX: minimal luminal irregularities RCA: minimal luminal irregularities Aspiration thrombectomy and PCI performed with resultant TIMI 3 flow in LAD and D1. 1824 post cath: Mot much different than the ECG above, but QOH: "OMI, Low confidence."
52 
Journal of the American Heart Association
APRIL 7, 2025
BackgroundStrain assessed by cardiac magnetic resonance (CMR) is a key prognostic indicator in myocardial infarction. However, the strain characteristics and prognostic value in myocardial infarction with nonobstructive coronary arteries (MINOCA) with different causes are unclear.
All About Cardiovascular System and Disorders
FEBRUARY 24, 2024
Arrhythmogenic Cardiomyopathy was better known as Arrhythmogenic Right Ventricular Dysplasia or ARVD and sometimes as Arrhythmogenic Right Ventricular Cardiomyopathy or ARVC earlier. A study published in JACC has compared the phenotypic expression and clinical outcomes in patients with arrhythmogenic cardiomyopathy [2].
BoardVitals - Cardiovascular
FEBRUARY 10, 2020
Because it’s the month that houses Valentine’s Day, it is obviously the most appropriate month to share information about takotsubo cardiomyopathy. Takotsubo cardiomyopathy is commonly known by a few other names as well – stress cardiomyopathy, apical ballooning syndrome, broken heart syndrome, and stress-induced cardiomyopathy.
Hypertension Journal
DECEMBER 28, 2023
The noradrenergic phenotype had significantly more atherosclerotic complications (composite end point of type 1 myocardial infarction and symptomatic peripheral artery disease; odds ratio, 3.58 [95% CI, 1.59–8.83];P=0.003), 0.57];P=0.002).
DAIC
APRIL 30, 2024
Myocardial infarctions , commonly known as “heart attacks,” are on the rise, resulting in a significant number of deaths each year. We are already employing the same cardiac spheroids on patients with ischemic cardiomyopathy,” comments Asst.
105 HeartRhythm
APRIL 30, 2024
Sudden cardiac death (SCD) risk stratification is based on clinically recognized risk factors (RF), such as reduced left ventricular (LV) ejection fraction (EF), heart failure (HF), prior myocardial infarction (MI), and syncope. These RFs fail to capture the majority of SCDs.
Journal of the American Heart Association
FEBRUARY 23, 2024
BackgroundRecent studies have indicated high rates of future major adverse cardiovascular events in patients with Takotsubo cardiomyopathy (TC), but there is no well‐established tool for risk stratification. Journal of the American Heart Association, Ahead of Print.
Open Heart
OCTOBER 7, 2024
Background Takotsubo cardiomyopathy (TC) is an established differential diagnosis of myocardial infarction with non-obstructive coronaries with significant interest but limited data on prognostication. We reviewed the characteristics and in-hospital outcomes and developed a novel risk score for TC.
52 
DAIC
JUNE 19, 2024
Within the last six months, separate AI-ECG algorithms for detecting Low Ejection Fraction (Anumana), Hypertrophic cardiomyopathy (Viz.ai), and Occlusion Myocardial infarction (Powerful Medical) have all been granted regulatory clearance (the latter under the EU MDR) and are in the early stages of deployment.
105 
European Journal of Heart Failure
OCTOBER 5, 2023
In this study, two independent cohorts were used to investigate for cardiovascular magnetic resonance (CMR) and genetic features of dilated cardiomyopathy (DCM) in individuals with coronary artery disease (CAD). Methods and results This study includes two cohorts.
DAIC
MARCH 21, 2024
Impella Left Sided Blood Pumps also are used when there is ongoing cardiogenic shock that occurs less than 48 hours after a severe heart attack (acute myocardial infarction), open-heart surgery, or when the heart is not functioning well due to a condition called cardiomyopathy.
Stroke Journal
JANUARY 30, 2025
Background:Clinical and genetic predispositions are significant in predicting atrial fibrillation (AF); however, their role in patients with hypertrophic cardiomyopathy (HCM) remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page ATMP101-ATMP101, February 1, 2025.
40 
HeartRhythm
APRIL 30, 2024
Scar burden on LGE-CMR imaging may be a risk marker for ventricular arrhythmia post-myocardial infarction (MI). There is an unmet need for better risk stratification for sudden cardiac death in the era of primary prevention ICD therapy.
Journal of the American Heart Association
JANUARY 9, 2024
BackgroundHeart failure is a common complication after myocardial infarction (MI) and is associated with increased mortality. Whether remote heart failure symptoms assessment after MI can improve risk stratification is unknown.
Stroke: Vascular and Interventional Neurology
NOVEMBER 9, 2023
We aimed to investigate the safety of intravenous tissue plasminogen activator (IV tPA) and mechanical thrombectomy (MT) for acute ischemic stroke (AIS), and compare the functional outcome in cardiomyopathy patients with and without HF. This finding was regardless of the type of intervention received, including tPA (15.9% 22.3%, p= 0.321).
Dr. Paddy Barrett
MAY 17, 2024
Sudden heart failure has been well described after the death of a loved one and is known as Takatubo Cardiomyopathy after the shape of a Japanese octopus fishing pot. That event might have been a heart rhythm issue or even a cardiac arrest. This is more commonly known as ‘Broken Heart Syndrome.
104 
Open Heart
AUGUST 25, 2023
Background Consensus guidelines support the use of implanted cardioverter-defibrillators (ICD) for primary prevention of sudden cardiac death in patients with either non-ischaemic or ischaemic cardiomyopathy with left ventricular ejection fraction (LVEF) ≤35%. vs 19.1%, p<0.0001) and myocardial infarction (56.1%
Dr. Smith's ECG Blog
NOVEMBER 12, 2020
Clin Chem [Internet] 2020;Available from: [link] Smith mini-review: Troponin in Emergency Department COVID patients Cardiac Troponin (cTn) is a nonspecific marker of myocardial injury. In normal times, the most common use of cTni is in diagnosing, or ruling out, acute myocardial infarction (AMI, a subcategory of acute myocardial injury.
Dr. Smith's ECG Blog
DECEMBER 5, 2016
There is ST elevation in V2 and V3 There are inverted T-waves in V2 and V3 There are prominent U-waves in V2 and V3 Many responders were worried about ischemia or hypertrophic cardiomyopathy. Here was Massimo's response: "I'm very sure of Early Repolarization (ERP) diagnosis in this case. See this post on Benign T-wave Inversion.
52 
Wellnest
JUNE 1, 2023
And, addressing myocardial infarction, recent studies have shown that 1-4% of Athletes untimely die due to myocarditis caused by COVID-19. Covid-19 and Risk of Myocarditis in Athletes: Recent Studies There is growing evidence that the SARS-CoV-2 version of the Covid-19 virus can directly infiltrate myocardial cells.
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EMS 12-Lead
JUNE 1, 2022
Detailed Considerations LBBB and Myocardial Infarction In the emergent setting it’s important to assess LBBB through the lens of the Smith-modified Sgarbossa criteria, especially in a context that is clinically consistent with Acute Coronary Syndrome. Left bundle branch block-induced cardiomyopathy: Myth or reality?
Wellnest
DECEMBER 11, 2023
HIV and Cardiovascular Disease: HIV infection itself is associated with an increased risk of cardiovascular disease and can double the risk of CVDs, including myocardial infarction and stroke. Plus, abacavir, an NRTI, has been linked to an increased risk of myocardial infarction.
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