The American Journal of Cardiology

JANUARY 30, 2024

Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic heart disease inherited in an autosomal dominant pattern with an estimated prevalence of …

Cardiomyopathy 71

Cardiomyopathy Heart Disease 71

Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Stroke Strokes 81

Med Page Today

MARCH 10, 2025

(MedPage Today) -- Genetic testing for hereditary arrhythmia and cardiomyopathy in an area with known founder effects on local genetic variants had a high yield in identification of pathogenic variants by taking into account the local population.

Heart Disease 74

Heart Disease Cardiomyopathy Arrhythmia 74

American College of Cardiology

NOVEMBER 16, 2024

The goal of the VANISH2 trial was to compare endocardial catheter ablation with conventional antiarrhythmic drug (AAD) therapy as a first-line treatment for infarct-related ventricular tachycardia (VT) in ischemic cardiomyopathy.

Tachycardia 68

Tachycardia Ablation Heart Disease Cardiomyopathy 68

DAIC

JUNE 4, 2024

American College of Cardiology (ACC) and American Heart Association (AHA) Issue New Hypertrophic Cardiomyopathy (HCM) Management Guidelines 2. New Study Published in JACC: Heart Failure Reveals that Despite Significant Efforts to Improve Acute Heart Failure Treatment Over the Past 20 Years, Management Remains Unchanged 3.

Preserved Ejection Fraction 105

Preserved Ejection Fraction Peripheral Arterial Disease Heart Failure Atrial Fibrillation 105

Science Daily - Heart Disease

MAY 13, 2024

People with the heart condition obstructive cardiomyopathy were able to use significantly more oxygen while exercising after taking the investigational drug aficamten, according to a new study.

Exercise 127

Exercise Cardiomyopathy 127

Open Heart

JANUARY 27, 2022

Objectives (1) To evaluate the prevalence and hospitalisation rate of COVID-19 infections among patients with dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM) in the Royal Brompton and Harefield Hospital Cardiovascular Research Centre (RBHH CRC) Biobank. (2) of the cardiomyopathy cohort reporting COVID-19 symptoms.

COVID-19 52

COVID-19 Cardiomyopathy Hospital Heart Disease 52

Heart BMJ

AUGUST 26, 2024

With this study, we aimed to estimate the prevalence of structural heart disease (SHD) and decipher the prognostic implications of CMR in selected patients presenting with significant VAs. A change in diagnosis after use of CMR ranged from 21% to 66% with a pooled average of 35% (29%–41%). to 2.42).

Arrhythmia 96

Arrhythmia Cardiomyopathy Heart Disease Tachycardia 96

Frontiers in Cardiovascular Medicine

JANUARY 31, 2024

Introduction We conducted a study to determine the prevalence of structural heart disease in patients with CF, the characteristics of a cardiomyopathy not previously described in this population, and its possible relationship with nutritional deficiencies in CF.

Cardiomyopathy 64

Cardiomyopathy Transplant Pulmonary Heart Disease 64

Science Daily - Heart Disease

JULY 3, 2024

Drosophila -- known as fruit flies -- are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy. Researchers now show a way to significantly cut the time needed for that analysis while utilizing more of the heart region, using deep learning and high-speed video microscopy.

Cardiomyopathy 124

Cardiomyopathy Research 124

Science Daily - Heart Disease

NOVEMBER 21, 2024

A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single 'aberrant' genetic variant, as was previously thought, finds a new study.

Cardiomyopathy 108

Cardiomyopathy 108

Journal of Cardiovascular Electrophysiology

JANUARY 13, 2025

Mutations in RyR2 and its dysfunction are implicated in various congenital heart diseases (CHDs). ABSTRACT Ryanodine receptor 2 (RyR2) protein, a calcium ion release channel in the sarcoplasmic reticulum (SR) of myocardial cells, plays a crucial role in regulating cardiac systolic and diastolic functions.

Congenital Heart Disease 40

Congenital Heart Disease Electrophysiology Congenital Heart Disease 40

HeartRhythm

AUGUST 18, 2024

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare genetic heart disease associated with life-threatening ventricular arrhythmias. Diagnosis of ARVC is based on the 2010 Task Force Criteria (TFC), application of which often requires clinical expertise at specialized centers.

Cardiomyopathy 40

Cardiomyopathy Arrhythmia Heart Disease 40

Science Daily - Heart Disease

DECEMBER 7, 2023

Researchers have laid the foundation for the development of a gene therapy for the genetic heart disease arrhythmogenic cardiomyopathy (ACM). Their approach, based on replacement of the PKP2 gene, led to significant structural and functional improvements in laboratory models of the disease.

Heart Disease 40

Heart Disease Laboratory Cardiomyopathy Research 40

Science Daily - Heart Disease

MARCH 27, 2024

Young adults who were prescribed stimulant medications for attention-deficit/hyperactivity disorder (ADHD) were significantly more likely to develop cardiomyopathy (weakened heart muscle) compared with those who were not prescribed stimulants, in a new study.

Cardiomyopathy 110

Cardiomyopathy 110

HeartRhythm

APRIL 30, 2024

Over the past decade, the care of athletes with a genetic heart disease (GHD) has been changing with growing support for their return-to-play (RTP). Currently, G+/P- patients with hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS) are allowed but recommended to have continued follow up.

Heart Disease 40

Heart Disease Cardiomyopathy Tachycardia Outcomes 40

HeartRhythm

APRIL 30, 2024

Ventricular Tachycardia (VT) is an important cause of morbidity and mortality in structural heart Disease. Current literature is limited in direct comparison of VT in ischemic (ICM) compared to non-ischemic cardiomyopathy (NICM).

Tachycardia 40

Tachycardia Cardiomyopathy Heart Disease Ablation 40

HeartRhythm

JUNE 24, 2024

The Purkinje network plays an important role in the occurrence and maintenance of ventricular fibrillation (VF) in patients with structural heart disease and idiopathic VF. Recently, the involvement of the Purkinje network has been proven in some patients with hypertrophic cardiomyopathy (HCM).1,2

Cardiomyopathy 40

Cardiomyopathy Ablation Heart Disease 40

Journal of Cardiovascular Electrophysiology

NOVEMBER 7, 2024

Catheter ablation of atrial fibrillation in infiltrative cardiomyopathies ABSTRACT Atrial and ventricular arrhythmias are common in patients with Infiltrative heart diseases. Catheter ablation is a safe and effective modality for the treatment of AF in infiltrative cardiomyopathy.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Cardiomyopathy Arrhythmia 40

Circulation: Cardiovascular Imaging

NOVEMBER 2, 2023

Infiltrative cardiomyopathies comprise a broad spectrum of inherited or acquired conditions caused by deposition of abnormal substances within the myocardium. Advanced disease presents as heart failure and cardiac arrhythmias conferring poor prognosis. thereby eliminating the need for endomyocardial biopsy in most cases.

Cardiomyopathy 40

Cardiomyopathy Cardiovascular Imaging Heart Failure Arrhythmia 40

HeartRhythm

APRIL 30, 2024

The ultimate efficacy of these advanced treatments likely depends on the underlying heart disease and comorbidities. The outcome of refractory ES pts treated with PSB with ischemic (ICM) versus non-ischemic (NICM) cardiomyopathy substrates is unknown.

Cardiomyopathy 40

Cardiomyopathy Heart Disease Outcomes 40

HeartRhythm

APRIL 30, 2024

Hypertrophic cardiomyopathy (HCM) is a common, potentially genetic heart disease with an estimated prevalence of 1:500 that is characterized clinically by unexplained left ventricular hypertrophy. Concomitant QTc prolongation > 480 ms occurs in 13% of patients with HCM.

Cardiomyopathy 40

Cardiomyopathy Heart Disease 40

Medical Xpress - Cardiology

DECEMBER 3, 2024

Food and Drug Administration has approved a drug developed at Stanford Medicine that offers hope to people diagnosed with a rare cardiovascular disease, transthyretin amyloid cardiomyopathy, or ATTR-CM.

Heart Disease 40

Heart Disease Cardiomyopathy Cardiovascular Disease 40

All About Cardiovascular System and Disorders

FEBRUARY 14, 2024

All these features together in a cyanotic congenital heart disease is characteristic of tricuspid atresia. Fragmented QRS is a marker of myocardial scar and consequent arrhythmias in ischemic and nonischemic cardiomyopathy.

Congenital Heart Disease 52

Congenital Heart Disease Congenital Heart Disease VSD 52

All About Cardiovascular System and Disorders

APRIL 30, 2024

Hypertrophic cardiomyopathy is a genetic disorder with a guarded prognosis which occurs in about 1:500 individuals. The most common symptom of hypertrophic cardiomyopathy is dyspnoea which occurs in 90% of cases and is due to elevated left ventricular diastolic pressures as a consequence of the diastolic dysfunction.

Cardiomyopathy 40

Cardiomyopathy Bicuspid/Mitral Document Arrhythmia 40

Journal of the American Heart Association

FEBRUARY 14, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundIschemic cardiomyopathy (ICM) is the end stage of ischemic heart disease, in which ventricular remodeling contributes to a fatal ventricular arrhythmia, worsens heart function and unfavorable outcomes, and is related to persistent chronic inflammation.

Ultrasound 45

Ultrasound Electrophysiology Cardiomyopathy Arrhythmia 45

Medical Xpress - Cardiology

MARCH 5, 2025

A new study has uncovered that a gene variant common in Oceanian communities was misclassified as a potential cause of heart disease, highlighting the risk of the current diversity gap in genomics research which can pose a greater risk for misdiagnosis of people from non-European ancestries.

Cardiomyopathy 49

Cardiomyopathy Heart Disease Research 49

Journal of Cardiovascular Electrophysiology

SEPTEMBER 7, 2023

Recent data suggests that high PVC burden may lead to the development of PVC-induced cardiomyopathy (PVC-CM) even in patients without structural heart disease. Conclusions Based on the available data in the literature, we conclude that AADs play important role in the treatment of PVC-induced cardiomyopathy.

Cardiomyopathy 40

Cardiomyopathy Pharmacology Coronary Artery Disease Ablation 40

Science Daily - Heart Disease

JANUARY 13, 2024

Uncertainty surrounding how truncated titin proteins (TTNtvs) cause dilated cardiomyopathy (DCM) and peripartum cardiomyopathy (PPCM) led to investigations that could better inform therapies for these conditions.

Cardiomyopathy 67

Cardiomyopathy 67

DAIC

APRIL 4, 2024

in clinical practice for patients with hypertrophic cardiomyopathy (HCM), a commonly inherited heart disease that often goes undetected. Three studies, presented at the American College of Cardiology ’s ( ACC ) Annual Scientific Session & Expo 2024 , have shown positive outcomes with real-world impact of Viz.ai

Electrocardiogram 89

Electrocardiogram Cardiomyopathy Hospital Technology 89

Journal of the American Heart Association

DECEMBER 24, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundHypertrophic cardiomyopathy (HCM) is a common heritable heart disease where the most frequently associated mutations occur in the myosinbinding protein C (MYBPC3) sarcomereassociated gene.

Cardiomyopathy 40

Cardiomyopathy Heart Disease 40

Frontiers in Cardiovascular Medicine

JANUARY 10, 2024

Introduction Heart transplantation (HT) is the only treatment option in children with heart failure secondary to cardiomyopathies and non-reparable congenital heart diseases. Results We identified 27 children (66.7% On a median follow-up of 35.07 months (IQR: 13.13–111.87),

Heart Transplant 59

Heart Transplant Transplant Arrhythmia Pacemaker 59

HeartRhythm

APRIL 30, 2024

Conduction system disturbance may represent an early manifestation of underlying structural heart disease, including infiltrative disorders such as sarcoidosis. Timely diagnosis has significant implications for clinical management, allowing for disease-modifying therapy or implantable cardioverter-defibrillator (ICD) insertion.

Defibrillator 40

Defibrillator Cardiomyopathy Heart Disease 40

HeartRhythm

JANUARY 30, 2024

Genotype, albeit to varying degrees, impacts the diagnosis, risk-stratification, and management of many genetic heart diseases (GHDs).1 Genotype, albeit to varying degrees, impacts the diagnosis, risk-stratification, and management of many genetic heart diseases (GHDs).1

Cardiomyopathy 40

Cardiomyopathy Tachycardia Heart Disease Research 40

Circulation: Arrhythmia and Electrophysiology

JUNE 5, 2024

First-line epicardial approach was indicated in arrhythmogenic right ventricular cardiomyopathy (ARVC) and postmyocarditis VT; in patients with idiopathic dilated cardiomyopathy (IDCM) and postmyocardial infarction, indications resulted from available imaging techniques or 12-lead VT morphology.

Ablation 40

Ablation Tachycardia Heart Disease Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

Left Bundle Branch Area Pacing (LBBAP) has emerged as an alternate pacing strategy to reduce the risk of pacing-induced cardiomyopathy (PICM) and improve cardiac synchronization. Data on LBBAP feasibility and outcomes in the pediatric population are limited to mixed cohorts that include adults with congenital heart disease (CHD).

Congenital Heart Disease 40

Congenital Heart Disease Pediatrics Congenital Cardiomyopathy 40

Dr. Smith's ECG Blog

JUNE 23, 2023

A 50-something male with unspecified history of cardiomyopathy presented in diabetic ketoacidosis (without significant hyperkalemia) with a wide complex tachycardia and hypotension. The fact that he has a cardiomyopathy argues for a more typical ventricular tachycardia, as does the absence of rSR' in lead V1. It is regular.

Tachycardia 52

Tachycardia Cardiomyopathy Arrhythmia Diabetes 52