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Clinical and Genetic Risk Factors Predict Atrial Fibrillation on the Basis of Hypertrophic Cardiomyopathy

Journal of the American Heart Association

BackgroundClinical and genetic predispositions are significant in predicting atrial fibrillation (AF); however, their role in patients with hypertrophic cardiomyopathy (HCM) remains unclear. Journal of the American Heart Association, Ahead of Print.

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PO-06-052 THE OCCURRENCE OF VENTRICULAR SEPTAL SCARRING, HEART FAILURE, AND GENETIC VARIANTS IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY AND ARRHYTHMIA: RESULTS FROM THE PHOENIX CARDIAC GENETIC REGISTRY (PCGR).

HeartRhythm

Genetic predisposition to ventricular scarring is associated with heart failure and ventricular arrhythmia. Although many pathogenic variants have been shown to predispose patients to poor outcomes, the impact of many VUS remains uncharacterized.

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Genome‐Wide Association Study for Resting Electrocardiogram in the Qatari Population Identifies 6 Novel Genes and Validates Novel Polygenic Risk Scores

Journal of the American Heart Association

Genetic predisposition to long QT syndrome was explored using rare variant analysis.ResultsSeventyfour independent loci were obtained with genomewide significance across the 6 traits (P<5108). Middle Eastern PRSs were developed using clumping and thresholding, and their performance was compared with 26 published PRSs.

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The Role of Genetics in Heart Disease: Can You Prevent It?

MIBHS

Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries.

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Alcohol and Heart Health: Understanding the Impact of Drinking on Your Heart

MIBHS

Heavy and repeated binge drinking can lead to alcoholic cardiomyopathy, a condition in which the heart muscle weakens and struggles to pump blood efficiently. The Role of Genetics and Individual Risk Factors Individual risk factors play a crucial role in how alcohol affects the heart.

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Abstract TMP101: Clinical and Genetic Risk Factors Predict Atrial Fibrillation Based on Hypertrophic Cardiomyopathy

Stroke Journal

Background:Clinical and genetic predispositions are significant in predicting atrial fibrillation (AF); however, their role in patients with hypertrophic cardiomyopathy (HCM) remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page ATMP101-ATMP101, February 1, 2025.

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Reduced Ejection Fraction in Elite Endurance Athletes: Clinical and Genetic Overlap With Dilated Cardiomyopathy

Circulation

BACKGROUND:Exercise-induced cardiac remodeling can be profound, resulting in clinical overlap with dilated cardiomyopathy, yet the significance of reduced ejection fraction (EF) in athletes is unclear.