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The most productive journals were Europace and the Journal of Interventional Cardiac Electrophysiology. Keywords with strong recent citation bursts included tissue, cardiomyopathy, and closed chest ablation.ConclusionPFA is becoming established as a viable alternative for AF ablation, showing promising safety and efficacy.
Nevertheless, studies on the long-term outcomes of catheter ablation in patients with dilated cardiomyopathy are limited. Method Patient baseline characteristics and electrophysiological parameters were examined to identify the predictors of atrial fibrillation recurrence following catheter ablation.
There is almost always the possibility of exceptions ( ie, prior infarction or cardiomyopathy that might result in a very abnormal baseline tracing ). In this case report — the 69-year old woman ( who incidently had a history of both coronary disease and cardiomyopathy ) — remained in sustained VT for 5 days without hemodynamic deterioration.
Cardiac sarcoidosis (CS), a rare condition characterized by non-caseating granulomas, can manifest with symptoms such as atrioventricular block and ventricular tachycardia (VT), as well as mimic inherited cardiomyopathies. A 58-year-old woman presented with sustained VT with a prior diagnosis of hypertrophic cardiomyopathy (HCM).
BackgroundIschemic cardiomyopathy (ICM) is the end stage of ischemic heart disease, in which ventricular remodeling contributes to a fatal ventricular arrhythmia, worsens heart function and unfavorable outcomes, and is related to persistent chronic inflammation. Journal of the American Heart Association, Ahead of Print.
Cardiac electrophysiologic and Cardiovascular involvement has long been important in the surveillance, care, and prognosis of patients with both BMD and DMD, and is the leading cause of mortality in patients with DMD.
Additionally, RyR2 mutations have been associated with multiple genetic cardiomyopathies, such as left ventricular non-compaction cardiomyopathy (LVNC), arrhythmogenic right ventricular cardiomyopathy (ARVC), hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM).
BackgroundAbnormal substrate on invasive electroanatomic mapping (EAM) correlates with areas of myocardial thinning and fibrofatty replacement in Arrhythmogenic Cardiomyopathy (ACM).
Arrhythmogenic Cardiomyopathy was better known as Arrhythmogenic Right Ventricular Dysplasia or ARVD and sometimes as Arrhythmogenic Right Ventricular Cardiomyopathy or ARVC earlier. A study published in JACC has compared the phenotypic expression and clinical outcomes in patients with arrhythmogenic cardiomyopathy [2].
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Atrial cardiomyopathy is a condition that causes electrical and contractile dysfunction of the atria, often along with structural and functional changes.
Hypertrophic cardiomyopathy (HCM) is associated with a predisposition to lethal ventricular arrhythmias. LGE scar burden on MRI is thought to contribute to this risk, but its impact on electrophysiological substrate is not well understood.
Atrial fibrillation (AF) in patients with hypertrophic obstructive cardiomyopathy (HOCM) may be caused by a primary atrial myopathy. Whether HOCM-related atrial myopathy affects mainly electrophysiological properties of the left atrium (LA) or also the right atrium (RA) has never been investigated.
The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). Ommen, MD, FACC , medical director of the Mayo Hypertrophic Cardiomyopathy Clinic and chair of the guideline writing committee.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Increased mitochondrial Ca2+uptake has been implicated in the QT prolongation and lethal arrhythmias associated with nonischemic cardiomyopathy. In a heterologous expression system, c-Src could bind MCU and phosphorylate MCU tyrosines.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Over the past decades, hypertrophic cardiomyopathy has become a contemporary treatable disease. Geographic disparities in ICD utilization were evident, highlighting the need to improve access to specialized care for patients with hypertrophic cardiomyopathy.
Circulation: Arrhythmia and Electrophysiology, Volume 16, Issue 11 , Page e012191, November 1, 2023. BACKGROUND:The cause of hypertrophic cardiomyopathy (HCM) in the young is highly varied. Atrioventricular AP (true AP) were distinguished from fasciculoventricular fibers (FVF) using standard invasive electrophysiology study criteria.
To improve arrhythmogenic cardiomyopathy (ACM) patient care four pillars of ACM research are necessary. The first pillar to improve ACM is cohort studies in which the genotype-specific natural history of disease is described, and subsequently genotype-specific risk calculators can be developed, such as the DSP and PLN risk calculators.
While PVCs may have various causes, a small number of individuals with PVCs develop cardiomyopathy in the absence of other potential etiologies. When correctly identified, patients with PVC-incuded cardiomyopathy can have dramatic improvement of their cardiomyopathy with treatment of their PVCs.
The EHRA/HRS/APHRS/SOLAECE Expert Consensus on Atrial Cardiomyopathies published in 2017 defined atrial cardiomyopathy as “any complex of structural, architectural, contractile, or electrophysiological changes affecting the atria.”1
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Population genomic screening for desmosome variants associated with arrhythmogenic right ventricular cardiomyopathy (ARVC) may facilitate early disease detection and protective intervention.
A 55 year old male with ischemic cardiomyopathy was referred to electrophysiology lab for VT ablation. A novel grid catheter, OPTRELL (Biosense Webster, CA) was used to map LV via retro-aortic approach.
Catheter ablation of atrial fibrillation in infiltrative cardiomyopathies ABSTRACT Atrial and ventricular arrhythmias are common in patients with Infiltrative heart diseases. Catheter ablation is a safe and effective modality for the treatment of AF in infiltrative cardiomyopathy.
Atrial tachycardia (AT) originating from the left atrial appendage (LAA) is uncommon and the most difficult arrhythmia to eliminate. Therefore, we present the case of a 5-year-old girl with tachycardia-induced.
Recent data suggests that high PVC burden may lead to the development of PVC-induced cardiomyopathy (PVC-CM) even in patients without structural heart disease. Conclusions Based on the available data in the literature, we conclude that AADs play important role in the treatment of PVC-induced cardiomyopathy.
Abstract Introduction It remains unclear if pacing induced cardiomyopathy (PICM) may be minimized by standard pacing of the right ventricle (RV) at sites other than the RV apex. Patients were excluded for Biventricular devices, and for alternative causes of cardiomyopathy. PICM occurred in 4.5% of RVMS patients, and 22.1%
Myocardial calcium (Ca2+) signaling plays a crucial role in contractile function and membrane electrophysiology. This narrative review evaluates the role of aberrant Ca2+ release synchrony in the pathophysiology of cardiomyopathies and ventricular arrhythmias.
Abstract Introduction In hypertrophic cardiomyopathy (HCM), atrial fibrillation (AF) has historically been regarded to have a deleterious impact on clinical course, strongly associated with progressive heart failure (HF) symptoms. Therefore, we evaluated the impact of AF on QoL utilizing patient reported outcome measures (PROMs).
Methods Two patients with ischemic cardiomyopathy and previously failed RF VT ablations were treated with PFA. Abstract Introduction Due to its unique features, pulsed field ablation (PFA) could potentially overcome some limitations of current radiofrequency (RF) ventricular tachycardia (VT) ablation.
Atrial cardiomyopathy represents structural and electrophysiologic abnormalities associated with atrial fibrillation (AF). Fibrosis, visualized with late gadolinium enhancement on cardiac magnetic resonance imaging (MRI), is associated with low voltage on electroanatomic mapping1, and ablation outcomes 2.
Complete left bundle branch block (CLBBB)-like QRS morphology of right ventricular pacing at pacemaker implantation satisfying the American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society criteria of CLBBB was associated with development of pacing induced cardiomyopathy.
Subsequent electrophysiological study findings identified the tachycardia as originating from the anterior limbus of the PFO. A 12-lead electrocardiogram revealed a narrow QRS complex tachycardia with a rate of 157 beats per minute and a prolonged RP relationship. Echocardiography indicated a severely reduced ejection fraction of 22%.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Epicardial approach in ventricular tachycardia (VT) ablation is still regarded as a second-step strategy, due to the risk of complications. The epicardial approach was considered useful if epicardial ablation was performed after epicardial mapping.
Brandão M, Desmoplakin Cardiomyopathy: Comprehensive Review of an Increasingly Recognized Entity. Clinical and electrophysiologic findings in patients with paroxysmal slowing of the sinus rate and apparent Mobitz type II atrioventricular block. Pacing and Clinical Electrophysiology, 35(7), e210–e213. J Clin Med. Reference 1.
Session 104) - What Is Really New in Electrophysiology That Will Change My Practice? The Guidelines Sessions at ACC.24 24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m. 12:15 p.m.
Jesse McLaren @ECGcases [link] [link] This case was kindly submitted by Dr. Paco Dardon (@PacoDardon), and it’s a privilege to present it as a formal review due to the many pathophysiological, and electrophysiological, phenomenon at play. Indeed, bedside Echocardiogram revealed severe left ventricular impairment of Takotsubo cardiomyopathy.
Impact of preceding systolic heart failure on risk of pacemaker-induced cardiomyopathy Abstract Background Pacemaker-induced cardiomyopathy is a well described phenomenon in patients with preserved ejection fraction at the time of permanent pacemaker implant.
Structural heart disease (SHD) was present in 120 patients (57%) and 20 patients (10%) had a primary cardiomyopathy. Twelve AFib/AFl episodes (8 with AFL, 4 with AFib) were associated with a thrombus, of which 8 (67%) patients had SHD, 2 (17%) had cardiomyopathy and 5 (42%) ventricular dysfunction.
million grant awarded to Georgia Tech by the United States Department of Defense Congressionally Directed Medical Research Programs (CDMRP) as part of the agency’s call for the development of less invasive treatment technologies for cardiovascular conditions associated with cardiomyopathy. The research is funded by a four-year, $7.8
The pathophysiological alterations and structural changes that occur in the atria, including architectural subcellular abnormalities fibrosis, are considered to cause atrial cardiomyopathy (atriopathy) predisposing to AF.
ABSTRACT Atrial fibrillation (AF) is the most common cause of arrhythmia-induced cardiomyopathy. Effective management strategies include medical therapy for rate and rhythm control, catheter ablation (CA), and goal-directed medical therapy.
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