Circulation: Genomic and Precision Medicine

JANUARY 30, 2024

Circulation: Genomic and Precision Medicine, Ahead of Print. BACKGROUND:Pathogenic variants in PKP2 (plakophilin-2) cause arrhythmogenic right ventricular cardiomyopathy, a disease characterized by life-threatening arrhythmias and progressive cardiomyopathy leading to heart failure.

Cardiomyopathy 72

Cardiomyopathy Arrhythmia Cardiac Function Heart Failure 72

Circulation: Heart Failure

FEBRUARY 10, 2025

Circulation: Heart Failure, Ahead of Print. Changes in TTN expression are associated with cardiac dysfunction, and TTN is one of the main genes linked to dilated cardiomyopathy (DCM). BACKGROUND:TTN (titin) is the third myofilament type of the cardiac sarcomere and performs important functions that include generating passive tension.

Cardiomyopathy 68

Cardiomyopathy Heart Failure Circulation 68

Circulation: Cardiovascular Interventions

FEBRUARY 10, 2025

Circulation: Cardiovascular Interventions, Ahead of Print. Hypertrophic cardiomyopathy is a common but underrecognized cardiac disorder characterized by a heterogenous phenotype that includes increased left ventricular thickness, outflow obstruction, diastolic dysfunction, and arrhythmia.

Cardiomyopathy 40

Cardiomyopathy Quality of Life Bicuspid/Mitral Cardiovascular Interventions 40

Circulation: Genomic and Precision Medicine

JANUARY 23, 2024

Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiomyopathy 75

Cardiomyopathy Circulation 75

Circulation

NOVEMBER 8, 2024

Circulation, Ahead of Print. BACKGROUND:Patients with hypertrophic cardiomyopathy without left ventricular outflow tract obstruction commonly experience reduced exercise capacity. Change in overall Kansas City Cardiomyopathy Questionnaire score was similar between groups. 95% CI, 0.63.5];P=0.006). points in exercise versus 0.74.0

Exercise 49

Exercise Cardiomyopathy Quality of Life Pulmonary 49

Circulation: Arrhythmia and Electrophysiology

NOVEMBER 29, 2023

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Atrial cardiomyopathy is a condition that causes electrical and contractile dysfunction of the atria, often along with structural and functional changes.

Cardiomyopathy 40

Cardiomyopathy Atrial Fibrillation Electrophysiology Arrhythmia 40

Circulation: Genomic and Precision Medicine

AUGUST 17, 2023

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 496-506, October 1, 2023. Previous studies on cardiomyopathies have been particularly valuable for clarifying pathological mechanisms in heart failure, an etiologically heterogeneous disease.

Cardiomyopathy 40

Cardiomyopathy Heart Failure Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4138334-A4138334, November 12, 2024. Ischemic cardiomyopathy, a severe cardiac condition resulting from prolonged myocardial ischemia, is characterized by ventricular dilation, dysfunction, and an increased risk of life-threatening arrhythmias.

Arrhythmia 40

Arrhythmia Cardiomyopathy Ischemia Circulation 40

Circulation

MARCH 16, 2025

Circulation, Volume 151, Issue 11 , Page e762-e762, March 18, 2025.

Cardiomyopathy 49

Cardiomyopathy Circulation 49

Circulation

OCTOBER 27, 2024

Circulation, Volume 150, Issue 18 , Page 1395-1397, October 29, 2024.

Cardiomyopathy 45

Cardiomyopathy Circulation 45

Circulation: Genomic and Precision Medicine

SEPTEMBER 28, 2023

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 452-461, October 1, 2023. When treatable causes are excluded, studies to define causes are often abandoned, resulting in a diagnosis of end-stage idiopathic cardiomyopathy. of patients with unexplained end-stage cardiomyopathy.

Heart Transplant 40

Heart Transplant Transplant Cardiomyopathy Pediatrics 40

Circulation: Heart Failure

NOVEMBER 8, 2024

Circulation: Heart Failure, Volume 17, Issue 12 , Page e011725, December 1, 2024. For most women, this physiological adaptation resolves at the end of pregnancy, but some women develop pathological dilatation and ultimately heart failure late in pregnancy or in the postpartum period, manifesting as peripartum cardiomyopathy (PPCM).

Cardiomyopathy 40

Cardiomyopathy Heart Failure Physiology Circulation 40

Circulation

JANUARY 12, 2025

Circulation, Volume 151, Issue 2 , Page 145-148, January 14, 2025.

Exercise 49

Exercise Cardiomyopathy Circulation 49

Circulation

APRIL 18, 2024

Circulation, Ahead of Print. Cardiac sarcoidosis is an infiltrative cardiomyopathy that results from granulomatous inflammation of the myocardium and may present with high-grade conduction disease, ventricular arrhythmias, and right or left ventricular dysfunction.

Cardiomyopathy 81

Cardiomyopathy Arrhythmia Circulation 81

Circulation

FEBRUARY 16, 2024

Circulation, Ahead of Print. BACKGROUND:Hypertrophic cardiomyopathy (HCM) is a common heritable myocardiopathy. This study may provide new insights into the molecular diagnosis and prevention of heritable cardiomyopathy as well as therapeutic options for FARS2-associated cardiomyopathy.

Cardiomyopathy 45

Cardiomyopathy Heart Failure Circulation 45

Circulation: Arrhythmia and Electrophysiology

AUGUST 30, 2024

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Increased mitochondrial Ca2+uptake has been implicated in the QT prolongation and lethal arrhythmias associated with nonischemic cardiomyopathy. In a heterologous expression system, c-Src could bind MCU and phosphorylate MCU tyrosines.

Cardiomyopathy 40

Cardiomyopathy Arrhythmia Electrophysiology Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142436-A4142436, November 12, 2024. Background:Stimulant-associated cardiomyopathy is an increasingly common cause of non-ischemic cardiomyopathy. Conclusions:The HeartPlus Clinic is a feasible treatment intervention for patients with stimulant-associated cardiomyopathy.

Cardiomyopathy 40

Cardiomyopathy Heart Failure Circulation Hospital 40

Circulation: Cardiovascular Imaging

NOVEMBER 2, 2023

Circulation: Cardiovascular Imaging, Volume 16, Issue 11 , Page e000081, November 1, 2023. Infiltrative cardiomyopathies comprise a broad spectrum of inherited or acquired conditions caused by deposition of abnormal substances within the myocardium. thereby eliminating the need for endomyocardial biopsy in most cases.

Cardiomyopathy 40

Cardiomyopathy Cardiovascular Imaging Heart Failure Arrhythmia 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4134590-A4134590, November 12, 2024. Background:Despite the role of cardiac catheterization for hemodynamic assessment and endomyocardial biopsy (EMB) in children with cardiomyopathy, data on procedure-related major adverse events (MAE) in this population is lacking. were females.

Cardiomyopathy 40

Cardiomyopathy Pediatrics Heart Transplant Heart Failure 40

Circulation

JULY 21, 2024

Circulation, Volume 150, Issue 4 , Page 299-301, July 23, 2024.

Cardiomyopathy 45

Cardiomyopathy Circulation 45

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4143083-A4143083, November 12, 2024. Cardiomyopathy and arrhythmia have been described in a small number of cases. Case Description:A 28-year-old G2P1 woman presented at 27 weeks gestation with progressive dyspnea and lower extremity edema.

Cardiomyopathy 40

Cardiomyopathy Arrhythmia Aortic Atrial Fibrillation 40

Circulation: Genomic and Precision Medicine

MARCH 28, 2025

Circulation: Genomic and Precision Medicine, Ahead of Print. CONCLUSIONS:These findings provide evidence for the role of DDR genes and pathways in anthracycline-induced cardiomyopathy and provide a framework for targeted therapeutic interventions.

Cancer 40

Cancer Cardiomyopathy Circulation 40

Circulation: Cardiovascular Imaging

JANUARY 8, 2025

Circulation: Cardiovascular Imaging, Ahead of Print. This can manifest as a multitude of pathologies including left ventricular dysfunction, myocarditis, cardiomyopathy, accelerated atherosclerosis, and coronary vasospasm.

Cardio Oncology 40

Cardio Oncology Atherosclerosis Cardiomyopathy Cancer 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4144727-A4144727, November 12, 2024. Introduction:Dilated cardiomyopathy (DCM) is a common cardiomyopathy characterized by ventricular dilatation and systolic dysfunction.

CMS 40

CMS Pediatrics Cardiomyopathy Circulation 40

Circulation

MARCH 10, 2024

Circulation, Volume 149, Issue 11 , Page 822-824, March 12, 2024.

Cardiomyopathy 49

Cardiomyopathy Circulation 49

Circulation

NOVEMBER 14, 2024

Circulation, Ahead of Print. BACKGROUND:The ability to predict recovery of left ventricular ejection fraction (LVEF) in response to guideline-directed therapy among patients with nonischemic cardiomyopathy is desired.

Cardiomyopathy 40

Cardiomyopathy Heart Failure Circulation 40

Circulation: Cardiovascular Imaging

MARCH 3, 2025

Circulation: Cardiovascular Imaging, Ahead of Print. m/s) than in the hypertrophic cardiomyopathy cohort (median iVP, 1.4 BACKGROUND:Noninvasive tools to measure myocardial stiffness are limited. m/s; interquartile range, 1.73.9 m/s; interquartile range, 1.01.8 m/s;P=0.011).

Cardiomyopathy 40

Cardiomyopathy Cardiovascular Imaging Circulation 40

Circulation: Heart Failure

JANUARY 8, 2025

Circulation: Heart Failure, Ahead of Print. P=0.001), Kansas City Cardiomyopathy Questionnaire (+26 versus +31;P=0.031), and 6-minute walk test distance (+194 feet versus +340 feet;P=0.026). The primary outcome was 1-year survival. versus +0.17;P=0.001),

Quality of Life 76

Quality of Life Heart Failure Pulmonary Cardiomyopathy 76

Circulation: Heart Failure

JANUARY 23, 2025

Circulation: Heart Failure, Ahead of Print. BACKGROUND:Changes in the phenotype and genotype in hypertrophic cardiomyopathy (HCM) are thought to involve the myocardium as well as extracardiac tissues.

Cardiomyopathy 40

Cardiomyopathy Aortic Heart Failure Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145572-A4145572, November 12, 2024. Introduction:Dilated cardiomyopathy (DCM) is one of the causative diseases of heart failure, caused by genetic mutations.

Cardiomyopathy 40

Cardiomyopathy Cardiac Function Heart Failure Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4147640-A4147640, November 12, 2024. Background:Dilated cardiomyopathy (DCM) is a complex condition characterized by the dilation and impaired contraction of the left ventricle, which ultimately leads to heart failure.

Cardiomyopathy 40

Cardiomyopathy Biomarkers Heart Failure Circulation 40

Journal of Cardiovascular Pharmacology

NOVEMBER 11, 2024

Therefore, this study investigated whether melatonin ameliorates dilated cardiomyopathy (DCM) by modulating M2-type polarization. Circulating melatonin levels were significantly decreased in DCM mice and were associated with LVEF. Circulating melatonin levels were significantly decreased in DCM mice and were associated with LVEF.

Cardiomyopathy 40

Cardiomyopathy Circulation Article 40

Circulation: Cardiovascular Imaging

MARCH 17, 2025

Circulation: Cardiovascular Imaging, Volume 18, Issue 3 , Page e018057, March 1, 2025.

Cardiovascular Imaging 40

Cardiovascular Imaging Cardiomyopathy Circulation 40

Circulation: Genomic and Precision Medicine

FEBRUARY 14, 2024

Circulation: Genomic and Precision Medicine, Ahead of Print. P<0.0001) and 99.76 (95% CI, 34.60–287.62;P<0.0001), P<0.0001), respectively.TBX20tvwas cosegregated with DCM/LVNC phenotype in 21 families for a combined LOD score of 4.53 (strong linkage).

Cardiomyopathy 40

Cardiomyopathy Congenital Heart Failure Aortic 40

Circulation

JULY 7, 2024

Circulation, Volume 150, Issue 2 , Page e64-e64, July 9, 2024.

Cardiomyopathy 45

Cardiomyopathy Circulation 45

Circulation

NOVEMBER 11, 2024

Circulation, Ahead of Print. Innovative strategies have emerged to rectify pathogenic variants that cause monogenic disorders such as hypertrophic, dilated, and arrhythmogenic cardiomyopathies and hypercholesterolemia.

Cardiovascular Disease 73

Cardiovascular Disease Innovation Cardiomyopathy Circulation 73

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4139929-A4139929, November 12, 2024. Background:Mid-ventricular obstruction (MVO) is a rare subtype of hypertrophic cardiomyopathy (HCM) , but it is associated with severe symptoms and worse clinical outcomes. Whereas the mechanisms of MVO has not fully elucidated.

Cardiomyopathy 40

Cardiomyopathy BMI Risk Factors Circulation 40