Med Page Today

SEPTEMBER 20, 2024

(MedPage Today) -- Better imaging parameters may exist for risk stratification in nonischemic dilated cardiomyopathy (NIDCM), based on a meta-analysis. The presence and extent of late gadolinium enhancement (LGE) on cardiac MRI was a significant.

Cardiomyopathy 98

Cardiomyopathy 98

Med Page Today

JUNE 21, 2024

(MedPage Today) -- As an adjunct to bypass surgery for ischemic cardiomyopathy, a cardiac shockwave therapy aimed at regenerating ischemic myocardium boosted left ventricular ejection fraction (LVEF) and physical function at 1 year in a small sham.

Cardiomyopathy 105

Cardiomyopathy 105

JAMA Cardiology

OCTOBER 1, 2024

This randomized clinical trial assesses whether cardioverter-defibrillator implantation is more effective than amiodarone therapy for the primary prevention of all-cause mortality and secondary prevention of sudden cardiac death, hospitalization for heart failure, and use of a pacemaker among patients with chronic Chagas cardiomyopathy.

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Defibrillator Cardiomyopathy Sudden Cardiac Death Pacemaker 77

Med Page Today

MAY 8, 2024

(MedPage Today) -- Updates to national guidelines for the management of hypertrophic cardiomyopathy (HCM) endorse cardiac myosin inhibitor use in certain cases, greenlight more intensive physical activity, and expand treatment options for young.

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Cardiomyopathy Exercise 111

CardiacWire

JULY 17, 2024

Lexeo Therapeutics gave the 5,000 Americans with Friedreich’s ataxia cardiomyopathy reason for optimism, publishing early results that suggest its LX2006 gene therapy could be able to treat FA cardiomyopathy. The post Lexeo LX2006 Shows Promise for Friedreich’s Ataxia Cardiomyopathy appeared first on Cardiac Wire.

Cardiomyopathy 59

Cardiomyopathy 59

DAIC

JULY 10, 2024

Findings from an observational analysis of ARISE-HF trial participants, newly-published in the Journal of the American College of Cardiology, JACC, shed light on the racial and ethnic disparities in diabetic cardiomyopathy (DbCM), which researchers note may have the potential to inform clinical practice, interventions, and policies.

Cardiomyopathy 113

Cardiomyopathy Diabetes Health Disparities Exercise 113

Medical Xpress - Cardiology

APRIL 4, 2024

Diabetic cardiomyopathy (DC) is a serious condition characterized by impaired heart function due to diabetes-related metabolic abnormalities. Diabetes is a global health burden. A whopping 536 million people worldwide struggle with diabetes.

Cardiomyopathy 107

Cardiomyopathy Diabetes 107

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Background Chagas cardiomyopathy (CHCM) is the most important clinical manifestation of Chagas disease. The analysis of cardiac miRNAs may contribute to predicting the progression to CHCM in Chagas indeterminate phase and/or to the differential diagnosis for cardiomyopathy.

Cardiomyopathy 84

Cardiomyopathy Circulation Biomarkers Laboratory 84

Frontiers in Cardiovascular Medicine

OCTOBER 7, 2024

A case of a 44-year-old man presenting with a family history of LMNA mutation and cardiac symptoms (dizziness, weakness, palpitations, and shortness of breath) congruent with dilated cardiomyopathy. Genetic testing revealed a novel likely pathogenic mutation of the LMNA gene (c.513G>A,

Cardiomyopathy 52

Cardiomyopathy 52

JAMA Cardiology

NOVEMBER 14, 2024

This patient-level meta-analysis of a variety of randomized clinical trials examines the association between mean Kansas City Cardiomyopathy Questionnaire treatment effects and the absolute differences in the proportion of patients experiencing clinically meaningful improvement.

Cardiomyopathy 48

Cardiomyopathy 48

Circulation

NOVEMBER 11, 2024

Introduction:Stress Induced Cardiomyopathy is increasingly becoming more prevalent with increasing awareness about disease condition with annual incidence of 30 cases/100000 per year and an incidence of 1-2% in the patients presenting with acute coronary syndrome.[1] for stress induced cardiomyopathy and found 10450 patients in the data base.

Cardiomyopathy 40

Cardiomyopathy Cardiac Arrest Risk Factors Hemorrhage 40

The New England Journal of Medicine

JANUARY 10, 2024

The author discusses the epidemiology and clinical presentation of peripartum cardiomyopathy, as well as the mechanistic basis for potential therapeutics.

Cardiomyopathy 75

Cardiomyopathy 75

Science Daily - Heart Disease

MAY 8, 2024

Experts released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The guideline reiterates the importance of collaborative decision-making with patients who have HCM and provides updated recommendations for the most effective treatment pathways for adult and pediatric patients.

Cardiomyopathy 103

Cardiomyopathy Exercise Pediatrics 103

Cardiovascular Diabetology

NOVEMBER 6, 2024

Although the exact role of mitophagy in the pathogenesis of diabetic cardiomyopathy (DCM) caused by type 2 diabetes mellitus (T2DM) remains controversial, recent studies revealed inhibition of mitophagy exacer.

Cardiomyopathy 52

Cardiomyopathy Diabetes Research 52

Cardiovascular Diabetology

NOVEMBER 1, 2024

Diabetic cardiomyopathy (DCM) is a serious complication in patients with type 2 diabetes mellitus, and its mechanisms are complex and poorly understood. Despite growing evidence suggesting that ferroptosis pla.

Cardiomyopathy 52

Cardiomyopathy Diabetes Research 52

Circulation

NOVEMBER 11, 2024

Ischemic cardiomyopathy, a severe cardiac condition resulting from prolonged myocardial ischemia, is characterized by ventricular dilation, dysfunction, and an increased risk of life-threatening arrhythmias. Arrhythmia, a common complication in ischemic cardiomyopathy, is associated with poor clinical outcomes.

Arrhythmia 40

Arrhythmia Cardiomyopathy Ischemia Circulation 40

All About Cardiovascular System and Disorders

FEBRUARY 24, 2024

Arrhythmogenic Cardiomyopathy was better known as Arrhythmogenic Right Ventricular Dysplasia or ARVD and sometimes as Arrhythmogenic Right Ventricular Cardiomyopathy or ARVC earlier. A study published in JACC has compared the phenotypic expression and clinical outcomes in patients with arrhythmogenic cardiomyopathy [2].

Cardiomyopathy 52

Cardiomyopathy Chest Pain Heart Transplant Arrhythmia 52

Circulation

NOVEMBER 11, 2024

The mortality rate of alcohol-related cardiomyopathy using ICD code I42.6 Alcoholic cardiomyopathy) was studied from 2001-2020. 100,000 deaths.Conclusions:The mortality trends associated with alcohol-related cardiomyopathy have not changed significantly over the past two decades. 100,000 deaths in four U.S

Cardiomyopathy 40

Cardiomyopathy Certification Circulation Research 40

All About Cardiovascular System and Disorders

DECEMBER 15, 2023

Idiopathic dilated cardiomyopathy Idiopathic dilated cardiomyopathy is a form of dilated cardiomyopathy with unknown etiology characterised by progressive left ventricular dilatation and systolic dysfunction. The incidence of idiopathic dilated cardiomyopathy varies from 3-10 cases per 100,000 population.

Cardiomyopathy 52

Cardiomyopathy General Cardiology 52

American College of Cardiology

JUNE 3, 2024

The following are key points to remember from a state-of-the-art review on arrhythmia-induced cardiomyopathy (AiCM).

Arrhythmia 75

Arrhythmia Cardiomyopathy Article 75

Nature Reviews - Cardiology

OCTOBER 10, 2024

Nature Reviews Cardiology, Published online: 11 October 2024; doi:10.1038/s41569-024-01074-2 In this Review, Mestroni and colleagues provide an overview of the pathophysiological mechanisms underlying dilated cardiomyopathy, including both genetic and non-genetic causes, and discuss the development of novel therapies, such as small molecules and gene (..)

Cardiomyopathy 52

Cardiomyopathy 52

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

Infiltration of the myocardium with various cell types, cytokines and chemokines plays a crucial role in the pathogenesis of cardiomyopathies including inflammatory cardiomyopathies and myocarditis. This review offers a comprehensive overview of the current knowledge of the immune landscape in cardiomyopathies based on etiology.

Cardiomyopathy 81

Cardiomyopathy 81

Frontiers in Cardiovascular Medicine

NOVEMBER 19, 2024

BackgroundRestrictive cardiomyopathy (RCM) is a rare cardiomyopathy often characterized by normal or reduced ventricular chamber volume and bi-atrial enlargement, caused mainly by mutations in the myonodal gene.

Cardiomyopathy 40

Cardiomyopathy Heart Transplant Transplant Electrocardiogram 40

HCPLive

APRIL 10, 2024

A trio of experts discuss their perspectives on the recent advancement in pharmacotherapy within the management of hypertrophic cardiomyopathy.

Cardiomyopathy 78

Cardiomyopathy 78

Frontiers in Cardiovascular Medicine

MARCH 6, 2024

Cardiomyopathy, a heterogeneous pathological condition characterized by changes in cardiac structure or function, represents a significant risk factor for the prevalence and mortality of cardiovascular disease (CVD). Research conducted over the years has led to the modification of definition and classification of cardiomyopathy.

Cardiomyopathy 59

Cardiomyopathy Diabetes Obesity Article 59

Medical Xpress - Cardiology

JANUARY 14, 2024

Acoramidis yields a significantly better four-step primary hierarchical outcome, including aspects of mortality and morbidity, than placebo for patients with transthyretin amyloid cardiomyopathy, according to a study published in the Jan. 11 issue of the New England Journal of Medicine.

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Cardiomyopathy Outcomes 75

Frontiers in Cardiovascular Medicine

MARCH 19, 2024

Background Precision medicine in paediatric cardiac channelopathy and cardiomyopathy has a rapid advancement over the past years. Results A total of 31 patients (11 cardiac channelopathy and 20 cardiomyopathy) were recruited. Results A total of 31 patients (11 cardiac channelopathy and 20 cardiomyopathy) were recruited.

Cardiomyopathy 64

Cardiomyopathy 64

Nature Reviews - Cardiology

MAY 27, 2024

Nature Reviews Cardiology, Published online: 28 May 2024; doi:10.1038/s41569-024-01044-8 Data from the SEQUOIA-HCM trial show that aficamten, a cardiac myosin inhibitor, increases exercise capacity and improves quality of life in patients with symptomatic obstructive hypertrophic cardiomyopathy.

Cardiomyopathy 64

Cardiomyopathy Quality of Life Exercise 64

American College of Cardiology

SEPTEMBER 20, 2024

What is the association of cardiac magnetic resonance (CMR) imaging–derived measurements with clinical outcomes in nonischemic dilated cardiomyopathy (NIDCM)?

Cardiomyopathy 51

Cardiomyopathy Outcomes Article 51

Frontiers in Cardiovascular Medicine

JUNE 28, 2024

Septic cardiomyopathy, a life-threatening complication of sepsis, can cause acute heart failure and carry a high mortality risk. These exosomes can both diagnose and treat septic cardiomyopathy, playing a crucial role in its development and progression. Current treatments have limitations.

Cardiomyopathy 52

Cardiomyopathy Article Technology Cardiac Function 52

American College of Cardiology

OCTOBER 2, 2024

What is the diagnostic yield of screening relatives of hypertrophic cardiomyopathy (HCM) patients and predictive factors for HCM development during long-term follow-up in relatives from gene-elusive families?

Cardiomyopathy 40

Cardiomyopathy Article 40

Cardiovascular Diabetology

JUNE 28, 2024

Diabetic cardiomyopathy (DCM) is characterized by cardiomyocyte hypertrophy, myocardial fibrosis. In recent years, the incidence of diabetes has been increasing rapidly, posing a serious threat to human health.

Cardiomyopathy 59

Cardiomyopathy Diabetes 59

American College of Cardiology

APRIL 17, 2024

What is the risk of mortality and composite cardiomyopathy-related outcomes associated with predicted deleterious variants in cardiomyopathy-associated genes?

Cardiomyopathy 54

Cardiomyopathy Outcomes Article 54

JAMA Cardiology

SEPTEMBER 24, 2024

This cohort study evaluates the association of late gadolinium enhancement with sudden cardiac death or relevant associated events among patients younger than 21 years with hypertrophic cardiomyopathy.

Sudden Cardiac Death 54

Sudden Cardiac Death Cardiomyopathy 54

Circulation

DECEMBER 21, 2023

microRNAs translocate into subcellular organelles to modify genes involved in diabetic cardiomyopathy. Malonylation, a posttranslational modification of Ago2, reduced the importing of Ago2 into mitochondria in diabetic cardiomyopathy. BACKGROUND:Diabetes is associated with cardiovascular complications.

Cardiomyopathy 81

Cardiomyopathy Diabetes Circulation 81

Circulation

NOVEMBER 11, 2024

Background:Stimulant-associated cardiomyopathy is an increasingly common cause of non-ischemic cardiomyopathy. Conclusions:The HeartPlus Clinic is a feasible treatment intervention for patients with stimulant-associated cardiomyopathy. Circulation, Volume 150, Issue Suppl_1 , Page A4142436-A4142436, November 12, 2024.

Cardiomyopathy 40

Cardiomyopathy Heart Failure Circulation Hospital 40

American College of Cardiology

JULY 12, 2024

What are the racial and ethnic differences among individuals with diabetic dilated cardiomyopathy at high risk for overt heart failure?

Cardiomyopathy 54

Cardiomyopathy Diabetes Heart Failure Article 54