DAIC

JULY 10, 2024

Findings from an observational analysis of ARISE-HF trial participants, newly-published in the Journal of the American College of Cardiology, JACC, shed light on the racial and ethnic disparities in diabetic cardiomyopathy (DbCM), which researchers note may have the potential to inform clinical practice, interventions, and policies.

Cardiomyopathy 113

Cardiomyopathy Diabetes Health Disparities Exercise 113

Science Daily - Heart Disease

MAY 8, 2024

Experts released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The guideline reiterates the importance of collaborative decision-making with patients who have HCM and provides updated recommendations for the most effective treatment pathways for adult and pediatric patients.

Cardiomyopathy 95

Cardiomyopathy Exercise Pediatrics 95

Medical Xpress - Cardiology

JANUARY 8, 2025

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS/MAPK pathway, according to a study published in JACC: Basic to Translational Science.

Cardiomyopathy 80

Cardiomyopathy 80

Med Page Today

SEPTEMBER 20, 2024

(MedPage Today) -- Better imaging parameters may exist for risk stratification in nonischemic dilated cardiomyopathy (NIDCM), based on a meta-analysis. The presence and extent of late gadolinium enhancement (LGE) on cardiac MRI was a significant.

Cardiomyopathy 93

Cardiomyopathy 93

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Background Chagas cardiomyopathy (CHCM) is the most important clinical manifestation of Chagas disease. The analysis of cardiac miRNAs may contribute to predicting the progression to CHCM in Chagas indeterminate phase and/or to the differential diagnosis for cardiomyopathy.

Cardiomyopathy 84

Cardiomyopathy Circulation Biomarkers Laboratory 84

DAIC

MARCH 6, 2024

Food and Drug Administration’s ( FDA ) Breakthrough Device Designation for their ECGvision-TTR Technology for early detection of ATTR-Cardiomyopathy. ECGvision-TTR was developed through state-of-the-art deep learning algorithms and offers the unique ability to analyze 12-lead ECG images to detect signatures of ATTR Cardiomyopathy.

Technology 105

Technology Cardiomyopathy Quality of Life Innovation 105

The New England Journal of Medicine

JANUARY 1, 2025

Among patients with transthyretin amyloidosis with cardiomyopathy, the risk of death from any cause and recurrent cardiovascular events was lower with vutrisiran treatment than with placebo.

Cardiomyopathy 74

Cardiomyopathy 74

American College of Cardiology

JUNE 3, 2024

The following are key points to remember from a state-of-the-art review on arrhythmia-induced cardiomyopathy (AiCM).

Arrhythmia 75

Arrhythmia Cardiomyopathy Article 75

DAIC

MARCH 26, 2024

Bristol Myers Squibb has announced that it will present data on CAMZYOS (mavacamten) for NYHA class II-III obstructive hypertrophic cardiomyopathy at the American College of Cardiology (ACC) Annual Scientific Session & Expo, ACC.24, 24, taking place April 6-8, 2024 in Atlanta, Georgia. 24 , taking place April 6-8, 2024 in Atlanta, Georgia.

Cardiomyopathy 104

Cardiomyopathy Research Heart Failure Hospital 104

JAMA Cardiology

NOVEMBER 14, 2024

This patient-level meta-analysis of a variety of randomized clinical trials examines the association between mean Kansas City Cardiomyopathy Questionnaire treatment effects and the absolute differences in the proportion of patients experiencing clinically meaningful improvement.

Cardiomyopathy 86

Cardiomyopathy 86

Medical Xpress - Cardiology

JANUARY 14, 2024

Acoramidis yields a significantly better four-step primary hierarchical outcome, including aspects of mortality and morbidity, than placebo for patients with transthyretin amyloid cardiomyopathy, according to a study published in the Jan. 11 issue of the New England Journal of Medicine.

Cardiomyopathy 85

Cardiomyopathy Outcomes 85

HCPLive

APRIL 10, 2024

A trio of experts discuss their perspectives on the recent advancement in pharmacotherapy within the management of hypertrophic cardiomyopathy.

Cardiomyopathy 78

Cardiomyopathy 78

Medical Xpress - Cardiology

FEBRUARY 21, 2024

Hypertrophic cardiomyopathy is a genetic condition that occurs in 1 in 500 people. It's often silent but can be a deadly killer.

Cardiomyopathy 75

Cardiomyopathy 75

Circulation

DECEMBER 21, 2023

microRNAs translocate into subcellular organelles to modify genes involved in diabetic cardiomyopathy. Malonylation, a posttranslational modification of Ago2, reduced the importing of Ago2 into mitochondria in diabetic cardiomyopathy. BACKGROUND:Diabetes is associated with cardiovascular complications.

Cardiomyopathy 81

Cardiomyopathy Diabetes Circulation 81

Medical Xpress - Cardiology

DECEMBER 3, 2024

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular condition. It is the leading cause of sudden cardiac death in young people and children, with an annual mortality rate of 1%. However, 10% to 20% of these patients have a significantly higher risk of sudden cardiac death.

Sudden Cardiac Death 81

Sudden Cardiac Death Cardiomyopathy 81

Circulation: Genomic and Precision Medicine

FEBRUARY 28, 2024

Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death. Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiomyopathy 72

Cardiomyopathy Sudden Cardiac Death Article Heart Failure 72

CardiacWire

JULY 17, 2024

Lexeo Therapeutics gave the 5,000 Americans with Friedreich’s ataxia cardiomyopathy reason for optimism, publishing early results that suggest its LX2006 gene therapy could be able to treat FA cardiomyopathy. The post Lexeo LX2006 Shows Promise for Friedreich’s Ataxia Cardiomyopathy appeared first on Cardiac Wire.

Cardiomyopathy 59

Cardiomyopathy 59

American College of Cardiology

DECEMBER 15, 2023

The following are key points to remember from a state-of-the-art paper on current and evolving multimodality cardiac imaging in managing transthyretin amyloid cardiomyopathy.

Cardiomyopathy 73

Cardiomyopathy Article 73

HeartRhythm

APRIL 15, 2024

Endocardial electrogram (EGM) characteristics in non-ischemic cardiomyopathy (NICM) have not been explored adequately for prognostication.

Cardiomyopathy 75

Cardiomyopathy Tachycardia 75

American College of Cardiology

MAY 2, 2024

What is the prognostic value of extent of late gadolinium enhancement (LGE) in predicting sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM)?

Sudden Cardiac Death 64

Sudden Cardiac Death Cardiomyopathy Article 64

Medical Xpress - Cardiology

SEPTEMBER 2, 2024

An international cardiology working group has published a consensus report on atrial cardiomyopathy in Europace.

Document 66

Document Cardiomyopathy Heart Rhythm 66

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Hypertrophic cardiomyopathy is the most common genetic cardiac disorder and is defined by the presence of left ventricular (LV) hypertrophy in the absence of a condition capable of producing such a magnitude of hypertrophy. Over the past decade, guidelines on the screening, diagnostic, and management protocols of pediatric primary (i.e.,

Pediatrics 87

Pediatrics Cardiomyopathy Heart Failure Exercise 87

JAMA Cardiology

OCTOBER 1, 2024

This randomized clinical trial assesses whether cardioverter-defibrillator implantation is more effective than amiodarone therapy for the primary prevention of all-cause mortality and secondary prevention of sudden cardiac death, hospitalization for heart failure, and use of a pacemaker among patients with chronic Chagas cardiomyopathy.

Defibrillator 65

Defibrillator Cardiomyopathy Sudden Cardiac Death Pacemaker 65

European Journal of Heart Failure

DECEMBER 5, 2024

Oral diuretic intensification was significantly prognostic of mortality amongst patients with transthyretin cardiomyopathy and occurred more often than HF hospitalization.

Outpatient 75

Outpatient Heart Failure Cardiomyopathy Hospital 75

Nature Reviews - Cardiology

MAY 27, 2024

Nature Reviews Cardiology, Published online: 28 May 2024; doi:10.1038/s41569-024-01044-8 Data from the SEQUOIA-HCM trial show that aficamten, a cardiac myosin inhibitor, increases exercise capacity and improves quality of life in patients with symptomatic obstructive hypertrophic cardiomyopathy.

Cardiomyopathy 61

Cardiomyopathy Quality of Life Exercise 61

American Heart News - Heart News

MAY 8, 2024

WASHINGTON and DALLAS (May 8, 2024) – The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM).

Cardiomyopathy 64

Cardiomyopathy Exercise 64

Circulation: Heart Failure

DECEMBER 18, 2023

Recent evidence suggests that loss of PRDM16 expression is associated with cardiomyopathy development in mice, although its role in human cardiomyopathy development is unclear. BACKGROUND:PRDM16 plays a role in myocardial development through TGF-β (transforming growth factor-beta) signaling.

Cardiomyopathy 75

Cardiomyopathy Heart Failure Pediatrics Circulation 75

JAMA Cardiology

SEPTEMBER 24, 2024

This cohort study evaluates the association of late gadolinium enhancement with sudden cardiac death or relevant associated events among patients younger than 21 years with hypertrophic cardiomyopathy.

Sudden Cardiac Death 66

Sudden Cardiac Death Cardiomyopathy 66

American College of Cardiology

MAY 8, 2024

The following are key points to remember from the 2024 AHA/ACC/multisociety guideline for the management of hypertrophic cardiomyopathy (HCM).

Cardiomyopathy 61

Cardiomyopathy Article 61

Dr. Smith's ECG Blog

APRIL 2, 2024

I was there and said, "No, I think this is all due to severe chronic cardiomyopathy and cardiac arrest due to primary ventricular fibrillation, not due to ACS." _ Why did I say that? Patient has an ICD, which is primarily placed in patients with cardiomyopathy. The bedside echo showed dilated cardiomyopathy with relatively thin walls.

Tachycardia 126

Tachycardia Pacemaker Cardiac Arrest Cardiomyopathy 126

American College of Cardiology

NOVEMBER 12, 2024

In patients with ischemic cardiomyopathy (ICM), what is the long-term survival of revascularization associated with coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI)?

Coronary Artery Bypass Graft 58

Coronary Artery Bypass Graft Cardiomyopathy Article 58

Cardiovascular Diabetology

JUNE 28, 2024

Diabetic cardiomyopathy (DCM) is characterized by cardiomyocyte hypertrophy, myocardial fibrosis. In recent years, the incidence of diabetes has been increasing rapidly, posing a serious threat to human health.

Cardiomyopathy 59

Cardiomyopathy Diabetes 59

Med Page Today

NOVEMBER 17, 2024

(MedPage Today) -- CHICAGO – A CRISPR-Cas9-based investigational therapy was linked with a drop in serum transthyretin (TTR) levels in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), according to phase I data. A single.

Cardiomyopathy 59

Cardiomyopathy 59

Cardiovascular Diabetology

JANUARY 8, 2024

Diabetic cardiomyopathy (DCM) is a major cause of mortality in patients with diabetes, and the potential strategies for treating DCM are insufficient. Melatonin (Mel) has been shown to attenuate DCM, however,

Cardiomyopathy 75

Cardiomyopathy Diabetes Research 75

American College of Cardiology

SEPTEMBER 25, 2024

In this week’s View, Dr. Eagle looks at risk stratification in nonischemic dilated cardiomyopathy using CMR imaging.

Cardiomyopathy 67

Cardiomyopathy Article 67

Circulation: Genomic and Precision Medicine

JANUARY 30, 2024

BACKGROUND:Pathogenic variants in PKP2 (plakophilin-2) cause arrhythmogenic right ventricular cardiomyopathy, a disease characterized by life-threatening arrhythmias and progressive cardiomyopathy leading to heart failure. Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiomyopathy 72

Cardiomyopathy Arrhythmia Cardiac Function Heart Failure 72

HCPLive

DECEMBER 5, 2024

Greg Duck, PA-C shared insights from his CAPP 2024 presentation on tailoring medical management and effective treatment of methamphetamine-induced cardiomyopathy.

Cardiomyopathy 59

Cardiomyopathy 59