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Advanced hemodynamics for prognostication in heart failure: the pursuit of the patient-specific tipping point

Frontiers in Cardiovascular Medicine

Methods Here, a mathematical and physiological framework to define the patient-specific tipping point of myocardial energetics is defined. A novel hemodynamic parameter known as the myocardial performance score (MPS), a marker of power and efficiency, is introduced that allows for the objective assessment of the physiological tipping point.