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Current and novel biomarkers in cardiogenic shock

European Journal of Heart Failure

A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end-organ dysfunction.

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Emergency interventions for cardiogenic shock due to decompensated aortic stenosis: a systematic review and meta-analysis

Open Heart

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. In-hospital mortality pooled estimated rates were 11% for eTAVI (CI 0.06 - 0.18) and for eBAV 40% (CI 0.28 - 0.54). Methods A systematic literature review and meta-analysis was performed.

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Clinical use and impact of mechanical circulatory support for myocardial infarction-related cardiogenic shock in the Netherlands: a registry-based propensity-matched analysis

Open Heart

Background Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes.

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Classification and Outcomes of Cardiogenic Shock in Children

American College of Cardiology

What are the characteristics and outcomes of cardiogenic shock (CS) in children hospitalized for acute decompensated heart failure (ADHF)?

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Windtree’s Istaroxime Scores in Cardiogenic Shock Trial

CardiacWire

Windtree Therapeutics’ istaroxime appears to have scored in its latest Phase 2b trial , showing that the steroidal drug significantly improves systolic blood pressure in cardiogenic shock patients. That could be a big deal in the cardiogenic shock space, which many believe is still in need of more effective treatments.

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Cardiogenic Shock in Older Adults: A Focus on Age-Associated Risks and Approach to Management: A Scientific Statement From the American Heart Association

Circulation

Cardiogenic shock continues to portend poor outcomes, conferring short-term mortality rates of 30% to 50% despite recent scientific advances. Age is a nonmodifiable risk factor for mortality in patients with cardiogenic shock and is often considered in the decision-making process for eligibility for various therapies.

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Patient Characteristics, Management and Long-term Outcomes of Patients with Cardiogenic Shock at a Large Safety Net Hospital

The American Journal of Cardiology

Publication date: Available online 24 January 2025 Source: The American Journal of Cardiology Author(s): Eric J. Hall, Colby R. Ayers, Nicholas S. Hendren, Christopher Clark, Amit Saha, Hadi Beaini, Isabella L. Alexander, Evan P. Gee, Ian R. McConnell, Emily S. Samson, Roslyn J. Saplicki, Christopher S. Grubb, Grant Tucker, Justin L.