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Current and novel biomarkers in cardiogenic shock

European Journal of Heart Failure

A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end-organ dysfunction.

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Emergency interventions for cardiogenic shock due to decompensated aortic stenosis: a systematic review and meta-analysis

Open Heart

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. In-hospital mortality pooled estimated rates were 11% for eTAVI (CI 0.06 - 0.18) and for eBAV 40% (CI 0.28 - 0.54). Methods A systematic literature review and meta-analysis was performed.

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Postcardiotomy Cardiogenic Shock Classification Scheme Accurately Predicts In-Hospital Mortality

American College of Cardiology

A simplified risk stratification model based on the cardiogenic shock (CS) classification system from the Society for Cardiovascular Angiography and Intervention (SCAI) effectively predicts in-hospital mortality in postcardiotomy (PC) patients, according to a retrospective, observational study.

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Clinical use and impact of mechanical circulatory support for myocardial infarction-related cardiogenic shock in the Netherlands: a registry-based propensity-matched analysis

Open Heart

Background Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes.

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National cardiogenic shock initiative study results show significant increase in heart attack survival

Medical Xpress - Cardiology

Published results of a large, national heart attack study show that patients with a life-threatening complication known as cardiogenic shock survived at a significantly higher rate when treated with a protocol developed by cardiologists at Henry Ford Health, in collaboration with 80 hospitals nationwide.

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Windtree’s Istaroxime Scores in Cardiogenic Shock Trial

CardiacWire

Windtree Therapeutics’ istaroxime appears to have scored in its latest Phase 2b trial , showing that the steroidal drug significantly improves systolic blood pressure in cardiogenic shock patients. That could be a big deal in the cardiogenic shock space, which many believe is still in need of more effective treatments.

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Classification and Outcomes of Cardiogenic Shock in Children

American College of Cardiology

What are the characteristics and outcomes of cardiogenic shock (CS) in children hospitalized for acute decompensated heart failure (ADHF)?