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The first task when assessing a wide complex QRS for ischemia is to identify the end of the QRS. The ST segment changes are compatible with severe subendocardial ischemia which can be caused by type I MI from ACS or potentially from type II MI (non-obstructive coronary artery disease with supply/demand mismatch). What do you think?
DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR. The ECG cannot diagnose the etiology of ischemia; it only the presence of ischemia, from whatever etiology.
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Accordingly, in the algorithm by Cai et al for patients with LBBB and ischemic symptoms ( See below ) — the first indication for PCI is clinical: patients with hemodynamic instability or acute heartfailure. So there is now high pre-test probability + refractory ischemia + Modified Sgarbossa + dynamic ECG changes.
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Assessment was severe sudden cardiogenicshock. Higher troponin correlated with more history of heartfailure, diabetes, and hypertension, as well as higher D-dimer, and nearly all inflammatory markers. Eur Heart J Acute Cardiovasc Care [Internet] 2020;9(1):62–9. They recorded an EC G: New ST Elevation.
All of this appears to be consistent with "No Reflow", or small vessel occlusion with persistent ischemia in spite of an open artery. His included cardiogenicshock, V Tach, AV block. --There is persistent ST elevation in leads V1-V4, with a lot of STE in V4 (another bad sign). Such large infarcts have many complications.
"Hi Steve wonder what you think of this ecg in a 60 yo woman w cp, known CAD" Presentation ECG (ECG 1): Here is her previous from one week prior when she presented with heartfailure and trops were "negative" (ECG 2): My response: "They both look like active ischemia. The previous ECG also shows active ischemia."
However, there is also significant tachycardia , with heart rate of 116, and known hypoxia. Whenever there is tachycardia, I am skeptical of OMI unless it has led to severely compromised ejection fracction with cardiogenicshock. The patient was started on heparin for possible NSTEMI vs demand ischemia.
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