article thumbnail

Myocardial intramural course may reduce left ventricular ejection fraction of patients suffering from coronary heart disease

Frontiers in Cardiovascular Medicine

However, it remains unclear whether MIC contributes to cardiac function impairment in patients with CHD. LVEF in patients of MIC-CHD was negatively correlated with the systolic stenosis degree of mural coronary artery (MCA) (r=0.6474, p=0.0123) and MIC length (r=0.5712, p=0.0414).ConclusionsThe

article thumbnail

Management of acute decompensated valvular heart disease

European Journal of Heart Failure

In acute heart failure caused by VHD, symptoms result from rapid haemodynamic changes and subsequent decline in cardiac function, and if left untreated, leads to acute decompensation and cardiogenic shock. Abstract Worldwide, valvular heart disease (VHD) is a common cause of hospitalization for acute heart failure.

article thumbnail

Relationship Between RNF213 p.R4810K and Echocardiographic Findings in Patients with Cerebrovascular Diseases: A Multicenter Prospective Cohort Study

Journal of the American Heart Association

BackgroundRING finger protein 213 (RNF213) p.R4810K is an established risk factor for moyamoya disease and intracranial artery stenosis in East Asian people. Recent evidence suggests its potential association with extracranial cardiovascular diseases, including pulmonary hypertension.

article thumbnail

Myocardial sodium–glucose cotransporter 2 expression and cardiac remodelling in patients with severe aortic stenosis: The BIO?AS study

European Journal of Heart Failure

Bar plots: in red, patients with low flow-low gradient (LF-LG) aortic stenosis; in blue, patients with normal flow-high gradient (HG) aortic stenosis; in black: controls. Main findings of the study. p  < 0.05 for HG and LF-LG vs. control; § p  < 0.05

article thumbnail

Case Report: Sudden very late-onset near fatal PD1 inhibitor-associated myocarditis with out-of-hospital cardiac arrest after >2.5 years of pembrolizumab treatment

Frontiers in Cardiovascular Medicine

After successful cardiopulmonary resuscitation, the initial diagnostic work-up showed elevated cardiac enzymes and a limited left-ventricular ejection fraction, while coronary angiography did not show relevant stenosis. Conclusion This case resembles the first description of a very late onset irMyocarditis, occurring over 2.5

article thumbnail

Case Report: Extended cardiopulmonary resuscitation in sudden cardiac arrest after acute myocardial infarction

Frontiers in Cardiovascular Medicine

We performed coronary angiography for the patient with ECMO support, indicating that the patient had an 80% critical stenosis of the left main coronary artery and an 80%–90% stenosis in the middle section of the left anterior descending artery with an aneurysm. Fortunately, there was no obvious stenosis in the right coronary artery.

article thumbnail

What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

Angiography : LMCA — 90-99% osteal stenosis. LCx — 50-69% stenosis of the 1st marginal branch; with 100% distal LCx occlusion. Cardiac function is poor, with akinesis of the LAD territory. Cath findings shown above in Dr. Nossen's discussion confirm multi-vessel disease , including 90-99% osteal stenosis of the LMCA.