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Healthy longevity-associated protein improves cardiac function in murine models of cardiomyopathy with preserved ejection fraction

Cardiovascular Diabetology

Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ag.

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Proteomic Associations of NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) in Heart Failure With Preserved Ejection Fraction

Circulation: Heart Failure

Background:NT-proBNP (N-terminal pro-B-type natriuretic peptide) levels are variably elevated in heart failure with preserved ejection fraction (HFpEF), even in the presence of increased left ventricular filling pressures. Circulation: Heart Failure, Ahead of Print.

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Increased Plasma Pyruvate Kinase M2 (PK‐M2) in Heart Failure: A Novel Biomarker Related to Cardiac Function and its Clinical Implications

Journal of the American Heart Association

U/mL,P<0.001), and these levels correlated with HF severity (New York Heart Association cardiac function class). Patients with reduced left ventricular ejection fraction had higher PKM2 concentrations than those with preserved ejection fraction (18.34.5 versus 7.82.3 versus 16.73.6

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Vericiguat combined with “new quadruple” therapy enhances cardiac function and life quality in patients with heart failure: a single-center prospective study

Frontiers in Cardiovascular Medicine

Patients diagnosed with reduced ejection fraction (HFrEF) and with heart failure with mildly reduced ejection fraction (HFmrEF) were treated with Vericiguat combined with “ARNI, BB, MRA, SGLT2i” therapy. vs. 43.1 ± 8.5%, P < 0.01), LVEDD (60.5 ± 8.1 vs. 58.2 ± 7.3 mm, mm, P < 0.01), NT-proBNP (4,567.8 ± 5,163.9

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Distinguishing heart failure subtypes: the diagnostic power of different cardiac magnetic resonance imaging parameters

Frontiers in Cardiovascular Medicine

Objectives The aim of this retrospective study was to explore the diagnostic potential of various cardiac parameters in differentiating between heart failure with preserved ejection fraction (HFpEF) and heart failure with mid-ranged and reduced ejection fraction (HFm + rEF), and to discern their relationship with normal cardiac function.

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Circulating neutrophil?related proteins associate with incident heart failure and cardiac dysfunction: The ARIC study

European Journal of Heart Failure

Associations of colchicine-related plasma proteins, incident heart failure (HF) and cardiac structure and function. HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction.

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Association between locomotor muscle quality and cardiac function during exercise in heart failure with preserved ejection fraction

European Journal of Heart Failure

Muscle quality and cardiac function in heart failure with preserved ejection fraction (HFpEF) during exercise. Therefore, the study aimed to determine the relationship between locomotor MQ and cardiac function during exercise in HFpEF. for all) but not in CTL.