HeartRhythm

APRIL 17, 2024

Peripheral electrical nerve stimulation (PENS) reportedly improves cardiac function after myocardial ischemia (MI) by rebalancing the cardiac autonomic nervous system. The dynamic and continuous influence of the PENS on autonomic and cardiac functioning based on cardiac self-repair is not well understood.

Cardiac Function 40

Cardiac Function Ischemia 40

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

Ca2+/calmodulin-dependent protein kinase IIδ (CaMKIIδ) is a prominent inducer of various cardiac disorders, which is mediated by 2 oxidation-sensitive methionine residues within the regulatory domain. Here, we extended this therapeutic concept toward potential clinical translation.

Cardiac Function 40

Cardiac Function Exercise Ischemia Cardiovascular Disease 40

HeartRhythm

APRIL 30, 2024

Loss of stromal interaction molecule 1 (STIM1) expression in smooth muscle cells protects against ischemia reperfusion (I/R) injury. Whether and how STIM1 expression in cardiomyocytes (CM) impacts cardiac remodeling in response to I/R injury is unclear.

Cardiac Function 40

Cardiac Function Ischemia 40

Journal of Cardiovascular Pharmacology

FEBRUARY 28, 2024

SNPiP-treated mice exhibited improved cardiac output and enhanced diastolic function, without an increase in heart rate. The NNA-activating effects included increased resilience to ischemia, modulation of energy metabolism preference, and activation of angiogenesis.

Cardiac Function 40

Cardiac Function Ischemia Article 40

Journal of Cardiovascular Pharmacology

NOVEMBER 16, 2023

The ischemia/reperfusion (I/R) injury mouse model and hypoxia/reoxygenation (H/R) cell model were established. Overexpression of ALKBH5 inhibited H/R-induced cardiomyocyte apoptosis and oxidative stress in vitro, and inhibited I/R-induced collagen deposition, cardiac function, and apoptosis in vivo.

Myocardial Infarction 40

Myocardial Infarction Cardiac Function Ischemia Article 40

Dr. Smith's ECG Blog

JULY 21, 2024

Cardiac function is poor, with akinesis of the LAD territory. There is no definite evidence of acute ischemia. (ie, Simply stated — t he patient was having recurrent PMVT without Q Tc prolongation, and without evidence of ongoing transmural ischemia. ( Some residual ischemia in the infarct border might still be present.

Arrhythmia 112

Arrhythmia Cardiogenic Shock Bradycardia Defibrillator 112

Dr. Smith's ECG Blog

MARCH 6, 2019

She requires maximal medical management per all current guidelines (including heparin and P2Y12 inhibitor per cardiology), as well as consideration for emergent cath in the case of persistent ischemia. So what will you do for this patient? They found an acute, total, thrombotic occlusion of the proximal LAD. They opened it. Patel et al.,

STEMI 52

STEMI Chest Pain Myocardial Infarction Ischemia 52