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Background:In out-of-hospital cardiacarrest (OHCA) patients with an initial shockable rhythm, epinephrine increases the likelihood of return of spontaneous circulation (ROSC), but its effect on neurological outcome remains uncertain.
Edited by Bracey, Meyers, Grauer, and Smith A 50-something-year-old female with a history of an unknown personality disorder and alcohol use disorder arrived via EMS following cardiacarrest with return of spontaneous circulation. The described rhythm was an irregular, wide complex rhythm.
Hence, the IV Amiodarone was once one of the 2nd-line choices for acute pharmacologic cardioversion in such patients without hemodynamic instability. Regarding AFib with WPW: The very rapid heart rate and at times extremely short R-R intervals put the patient with AFib and WPW at risk of cardiacarrest from VFib.
If the rhythm converts and then reverts to tachycardia with either adenosine or electricity, Neither one of those modalities should be attempted until some longer acting pharmacological solution is given. WPW does not always have delta waves on the baseline ECG. This is called "Concealed conduction".
This may result from fluctuations in heart rate or in nervous system activity or from pharmacologic treatment. Conduction and Refractoriness Alternans — entails variance of impulse propagation along some par t of the conduction system.
If cardiacarrest from hypokalemia is imminent (i.e., As I indicated above, in our cardiacarrest case, after pushing 40 mEq, the K only went up to 4.2 Crit Care Med 1991; 19:694) Concentrated Potassium Chloride Infusions in Critically Ill Patients with Hypokalemia The Journal of Clinical Pharmacology.
Intro:Mild hypothermia has proved clinically effective at improving outcomes in cardiacarrest patients for decades. Stroke, Volume 56, Issue Suppl_1 , Page ADP59-ADP59, February 1, 2025. Similarly, mild hypothermia has been shown to be neuroprotective in experimental stroke models. shiver response). shiver response).
Intro:Mild hypothermia has been clinically effective at improving outcomes in cardiacarrest patients for decades. To address a need for better strategies for cooling conscious subjects, we sought to promote mild hypothermia by pharmacological activation of heat-sensing nerve fibers in the thermoregulatory system.
When associated with appropriate clinical features (ie, personal history of cardiacarrest, polymorphic VT, non-vagal syncope, positive family history of sudden death at an early age, etc. ) — then spontaneous occurrence of a Brugada-1 ECG pattern is diagnostic of Brugada Syndrome.
mg experienced a 23% lower incidence of death from cardiovascular causes, resuscitated cardiacarrest, myocardial infarction, stroke, or urgent hospitalization for angina leading to coronary revascularization in a time-to-event analysis. Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review.
Pharmacological facilitation of primary percutaneous coronary intervention for acute myocardial infarction: is the slope of the curve the shape of the future? We are lucky this patient did not have a cardiacarrest while in the Waiting Room. JAMA [Internet] 2005;293(8):97986.
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