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This is mainly to account for the individual variation in anatomical location of right ventricular outflow tract, the main location of electrophysiological abnormalities in Brugada syndrome. Opinion is divided on the need for electrophysiology study. Spontaneous type 1 ECG has the highest number of points at 3.5,
But the full cohort of the CABANA trial did not show a significant reduction in the primary composite end point of death, disabling stroke, serious bleeding or cardiacarrest [7]. The study authors noted that lower than expected event rates and treatment crossovers could have affected the results of the trial. doi: 10.1001/jama.2019.0693.
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