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As expected, GLP-1s reduced MI risk by 9%, cardiacarrest by 22%, incident HF by 11%, ischemic stroke by 7%, and hemorrhagic stroke by 14%. GLP-1s also led to an 8% lower risk of dementia and 12% lower risk of Alzheimer’s disease. The less good news? Theres still no free lunch in healthcare.
Cox proportional hazards models were used to estimate hazard ratios (HR) for the composite and individual endpoints from CABANA trial (death, stroke, major bleeding or cardiacarrest) and CASTLE-AF trial (death or heart failure). years; 55% female, 28% frailty, 13% dementia), including 8% receiving CA. The mean follow-up was 1.8
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