Physiologically Speaking

SEPTEMBER 20, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Not only that, if evolution wired us to be lazy, then why do moderate to high levels of physical activity and aerobic fitness correlate with the best health outcomes? These genes are still with us today.

Exercise 114

Exercise Physiology Blood Pressure Obesity 114

Journal of Clinical Investigation - Cardiology

SEPTEMBER 17, 2024

BACKGROUND Metastatic hormone-sensitive prostate cancer (mHSPC) is androgen dependent, and its treatment includes androgen deprivation therapy (ADT) with gonadal testosterone suppression.

Cancer 75

Cancer Pharmacology Physiology Outcomes 75

Dr. Paddy Barrett

AUGUST 23, 2024

While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. A higher daily step count is also linked to significantly lower cancer, stroke and heart disease rates.

Exercise 116

Exercise Dementia Cancer Chronic Disease 116

Journal of Cardiothoracic Surgery

DECEMBER 7, 2023

Frailty develops as a result of age-related decline in many physiological systems and is associated with increased vulnerability to adverse outcomes following thoracic surgery. We prospectively tested our hypo.

Cancer 40

Cancer Physiology Pulmonary Outcomes 40

Physiologically Speaking

JANUARY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. However, there’s not great evidence that multivitamins benefit specific health outcomes. What if your calendar was the key to living a longer, healthier life? Nutritional insurance? Perhaps not.

Physiology 52

Physiology Diet Cardiovascular Disease BMI 52

Heart BMJ

MAY 10, 2024

HF affects around a million people in the UK and has a worse prognosis than most cancers. A timely diagnosis and initiation of evidence-based treatments are key to prevent hospitalisation and improve outcomes in this population. In this article, we will review the physiology of NPs and study their biological effects.

Biomarkers 52

Biomarkers Heart Failure Physiology Article 52

Physiologically Speaking

OCTOBER 9, 2024

Both lactate and BHB naturally increase in response to physiological stresses—lactate during intense exercise and BHB during prolonged fasting or low-carbohydrate diets. Physiologically Speaking is a reader-supported publication. LaKe is an ester composed of (S)-lactate and (R)-1,3-butanediol, a precursor to BHB.

Exercise 75

Exercise Physiology Diet Obesity 75