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Popular Diabetes Drug Class Lowered Risk of 10 Obesity-Associated Cancers

Med Page Today

(MedPage Today) -- GLP-1 receptor agonists lowered the risk of several obesity-associated cancers, a retrospective analysis of electronic health records suggested. Compared with insulin, GLP-1s were associated with a lower risk for developing.

Obesity 112
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Weight Loss Lowers Risk of Obesity-Related Cancer, Study Finds

HCPLive

In retrospective, observational research at ADA 2024, real-world weight loss was linked to a reduction in the risk of obesity-related cancers.

Obesity 80
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Have We Turned The Tide On Obesity?

Dr. Paddy Barrett

Obesity is one of the world’s biggest health crisis and only seems to be getting worse. For over 50 years, the rates of obesity have continued to rise worldwide 1. The most recent data on obesity has shown a decline for the first time in a very long time. Between 2020 and 2023, the rates of obesity dropped by about 2% 2.

Obesity 52
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Unhealthy visceral fat is associated with improved efficacy of immunotherapy in endometrial cancer

Journal of Clinical Investigation - Cardiology

Obesity is a known driver of endometrial cancer. In this issue of the JCI, Gómez-Banoy and colleagues investigated a cohort of patients with advanced endometrial cancer treated with immune checkpoint inhibitors targeting the interaction between programmed cell death receptor-1 (PD-1) and its ligand (PD-L1).

Cancer 75
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Study links gene mutations to heart rhythm risks seen in cancer patients

Medical Xpress - Cardiology

A UCLA-led research team has found that a gene mutation that affects insulin signaling in the heart may raise the risk of deadly abnormal heart rhythms in a subset of patients with cancer and could have implications for those with diabetes and obesity.

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Antithrombotic strategy in cancer patients comorbid with acute coronary syndrome and atrial fibrillation

Frontiers in Cardiovascular Medicine

It has been shown that patients with cancer have a longer expected life duration, benefiting from advanced medical therapy. A growing number of studies have elucidated the association between cancer and CVD. Moreover, different types of cancer have distinct risks, which may increase the complexity of antithrombotic therapy.

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NAFLD Presents Similar Risk for Adverse Outcomes Regardless of BMI

HCPLive

Patients with lean NAFLD had fewer metabolic comorbidities but maintained similar risk of NASH, cirrhosis, nonliver cancer, and mortality compared to their overweight and obese counterparts.

BMI 105