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API-CAT: Extended Anticoagulant Therapy With Reduced-Dose Apixaban Noninferior to Full-Dose in Patients With Active Cancer and VTE

American College of Cardiology

Extended anticoagulant therapy with a reduced-dose of apixaban was noninferior to extended therapy with a full-dose of apixaban in preventing recurrent venous thromboembolism (VTE) in patients with active cancer and proximal deep-vein thrombosis or pulmonary embolism, based on findings from the API-CAT trial presented at ACC.25

Cancer 71
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Upper extremity phlegmasia cerulea dolens complicating supra vena cava embolism in a cervical cancer patient: case report

Frontiers in Cardiovascular Medicine

Phlegmasia cerulea dolens (PCD) is a rare yet severe complication of deep vein thrombosis (DVT), characterized by a high amputation rate and mortality. Early diagnosis and treatment are crucial in managing this condition. PCD predominantly affects the lower extremities rather than the upper extremities.

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Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

DAIC

Abelacimab is currently in Phase 3 development with the lead indication for the prevention of stroke and systemic embolism in patients with atrial fibrillation (LILAC-TIMI 76), in addition to two studies in patients with cancer-associated thrombosis (ASTER and MAGNOLIA).

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Abstract TP225: Prevalence of Patent Foramen Ovale in Patients With Cancer-Related Stroke

Stroke Journal

Background and Purpose:Cancer increases the risk for acute ischemic stroke (AIS) and deep venous thrombosis. The role of paradoxical embolization as a stroke etiology in patients with cancer is uncertain. Our study investigated the relationship between cancer-related stroke and the presence of a patent foramen ovale (PFO).Methods:We

Cancer 40
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Abstract WP291: Prevalence of Medical Complications in Acute Ischemic Stroke Patients with versus without Cancer

Stroke Journal

Introduction:Acute ischemic stroke (AIS) patients are prone to medical complications such as acute kidney injury (AKI), acute myocardial infarction (AMI), deep vein thrombosis (DVT), gastrointestinal bleeding (GIB), pneumonia, pulmonary embolism (PE), sepsis, and urinary tract infection (UTI).

Cancer 40
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Myocardial infarction and pulmonary embolism in pancreatic cancer: a case report of two manifestations of Trousseau's syndrome

Frontiers in Cardiovascular Medicine

Subsequent investigations revealed pulmonary embolism, deep vein thrombosis, and imaging findings suggestive of pancreatic cancer. Following PCI, she was treated with optimal medical therapy, including dual antiplatelet therapy. Anticoagulation therapy was initiated to manage the VTE.