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This occurs most commonly in cancer (malignant pericardial effusion). Usually it is cancer of other organs spreading to the pericardium (secondary) rather than primary cancer of the pericardium which is very rare (mesothelioma). This may include medications, radiation, and surgery, depending on the type of cancer.
A middle-aged patient with lung cancer had presented to clinic complaining of generalized malaise, cough, and chest pain. Symptoms other than chest pain (malaise, cough in a cancer patient) 2. PR depression, which suggests pericarditis 4. Here is that ECG: What do you think? There is sinus tachycardia.
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