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Physiology Friday #237: An Evolutionary Perspective on Why Exercise Promotes Longevity

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. In my opinion, it’s even more important than diet and sleep, to an extent. What physiological mechanisms make moderate to high levels of activity so favorable, especially in our modern environment?

Exercise 114
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Disentangling the Metabolic Effects of the Ketogenic Diet and Ketone Supplements during Exercise

Physiologically Speaking

More contentious is whether ketogenic diets have any utility for exercise performance, especially among high-level athletes. Ketogenic diets are characterized as being very low in carbohydrates (less than 50 grams per day), modest in protein, and high in fat (more than 80% of total energy intake). What are ketones?

Diet 52
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Physiology Friday #240: Light Exposure Patterns Predict Your Risk of Death & Disease

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Many people carefully adjust their diets, follow specific exercise routines, and track their sleep with wearable devices, all in the pursuit of becoming the healthiest version of themselves. How can you apply these findings?

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Time-restricted Eating Increases Your Risk of Cardiovascular Death? Don't Buy the Headlines.

Physiologically Speaking

cardiovascular disease and cancer) mortality. regarding demographic, socioeconomic, dietary, and health-related factors collected via surveys and physiological measurements/lab tests. Adults with cardiovascular disease and cancer had a 107% and 204% greater risk, respectively, when they had an 8-hour eating window.

Diet 119
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Physiology Friday #202: Should You be Taking a Multivitamin for Cognitive Health? A New Study Suggests Yes.

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. It’s also likely that most people aren’t getting all of the nutrients they need from their diet even if they think they are. What if your calendar was the key to living a longer, healthier life?

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Physiology Friday #208: Creatine Boosts Cognitive Performance and Brain Energy Levels during Sleep Deprivation

Physiologically Speaking

Welcome to the Physiology Friday newsletter. On Wednesday, I published a post on the philosophy and physiology of an “exercise pill.” Physiologically Speaking is a reader-supported publication. When consumed via the diet (or used as a supplement), creatine increases our body’s phosphocreatine (PCr) stores.

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Exaggerated Claims about Newly Discovered "Exercise in a Pill"

Physiologically Speaking

Both lactate and BHB naturally increase in response to physiological stresses—lactate during intense exercise and BHB during prolonged fasting or low-carbohydrate diets. At the same time, BHB levels rise more gradually, paralleling the ketogenic state induced by fasting or ketogenic diets.