Physiologically Speaking

SEPTEMBER 6, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Diabetes, cardiovascular disease, cancer, Alzheimer’s disease, depression. Insulin resistance (characteristic of type 2 diabetes) causes a dysregulation in GLUT4 translocation and glucose uptake capacity.

Physiology 111

Physiology Exercise Research Diabetes 111

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

It has been shown that patients with cancer have a longer expected life duration, benefiting from advanced medical therapy. A growing number of studies have elucidated the association between cancer and CVD. Moreover, different types of cancer have distinct risks, which may increase the complexity of antithrombotic therapy.

Atrial Fibrillation 64

Atrial Fibrillation Cancer Embolism Coronary Artery Disease 64

Dr. Paddy Barrett

AUGUST 23, 2024

While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. A higher daily step count is also linked to significantly lower cancer, stroke and heart disease rates.

Exercise 116

Exercise Dementia Cancer Chronic Disease 116

Physiologically Speaking

OCTOBER 18, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Research has linked circadian rhythm disruptions to a wide range of health issues, including cardiovascular disease, diabetes, obesity, and even certain cancers.

Physiology 64

Physiology Diet Research Exercise 64

Physiologically Speaking

MARCH 8, 2024

Welcome to the Physiology Friday newsletter. On Wednesday, I published a post on the philosophy and physiology of an “exercise pill.” Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Acute sleep loss is also insidious.

Physiology 52

Physiology Exercise Diet Research 52

Hypertension Journal

DECEMBER 7, 2023

ET (endothelin) is a powerful vasoconstrictor 21-amino acid peptide present in many tissues, which exerts many physiological functions across the body and participates as a mediator in many pathological conditions. Hypertension, Ahead of Print.

Kidney Disease 45

Kidney Disease Hypertension Pulmonary Atherosclerosis 45

Physiologically Speaking

OCTOBER 9, 2024

Both lactate and BHB naturally increase in response to physiological stresses—lactate during intense exercise and BHB during prolonged fasting or low-carbohydrate diets. This could make LaKe an attractive option for weight management or as part of a dietary intervention for metabolic disorders like obesity and type 2 diabetes.

Exercise 75

Exercise Physiology Diet Obesity 75