Dr. Paddy Barrett

FEBRUARY 13, 2024

The world we live in means you are massively incentivised to eat in a way that makes you gain excess weight that will likely result in metabolic dysfunction and an increased risk of not only heart disease but many cancers and also dementia. While this is unfortunate, it is the world we live in. This is a way to tackle that problem.

Diet 105

Diet Diabetes Exercise Kidney Disease 105

Dr. Paddy Barrett

AUGUST 9, 2024

More than heart disease or cancer, the risk of dementia often creates much greater anxiety in the patients I see. And given that dementia is routinely in the top 5 leading causes of death, this concern is dually warranted. But can dementia be prevented? 14 Ways To Prevent Dementia. The answer is yes.

Dementia 116

Dementia Blood Pressure Obesity Cholesterol 116

Dr. Paddy Barrett

OCTOBER 11, 2024

Dementia is a leading cause of death and a major concern for most people as they age. Optimal metabolic health is linked to reduced rates of dementia, but the question again is whether the use of medications such as Ozempic might also delay the onset of dementia. Colorectal Cancer - 46% reduction. N Engl J Med.

Obesity 84

Obesity Cancer Dementia Coronary Artery Disease 84

Dr. Paddy Barrett

NOVEMBER 1, 2024

When you compare those in the highest fitness levels to those in the lowest fitness levels, the impact on early death, death from heart disease and cancer deaths is incredible 1. Cancer deaths: 43% reduction in risk. Dementia: 64% reduction in risk. Cancer deaths: 7% reduction in risk.

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Exercise Heart Disease Quality of Life Blood Pressure 120

Dr. Paddy Barrett

FEBRUARY 21, 2025

These stages can range from mild fatty liver infiltration to serious scarring and fibrosis terminating in liver cirrhosis and potentially liver cancer. Type 2 Diabetes When it comes to the increasing the risk of major chronic diseases such as cardiovascular disease, many cancers and dementia, type 2 diabetes plays a huge role.

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Obesity Diabetes Cardiovascular Disease Chronic Disease 81

Dr. Paddy Barrett

AUGUST 23, 2024

While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. 5 Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women.

Exercise 116

Exercise Dementia Cancer Chronic Disease 116

Dr. Paddy Barrett

MARCH 23, 2024

It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. J Gerontol A Biol Sci Med Sci.

Chronic Disease 106

Chronic Disease Quality of Life Dementia Cancer 106

Dr. Paddy Barrett

JANUARY 23, 2024

It kills almost twice as many people globally when compared to all cancers combined. Dementia Up to 40% of dementia cases could be prevented by focusing on modifiable risk factors 11. Those with high blood pressure from midlife have twice the risk of developing dementia over a 25-year follow-up 12. Ann Glob Health.

Heart Disease 106

Heart Disease Blood Pressure Dementia Atherosclerosis 106

Stroke Journal

FEBRUARY 1, 2024

The final model predicting stroke within 1 year following cancer diagnosis was derived using multivariable Fine-Gray regression with candidate predictors selected via backward elimination. Conclusion:We derived and validated a risk prediction model for ischemic stroke in patients with a new cancer diagnosis with good discrimination.

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Cancer Strokes Stroke Atrial Fibrillation 40

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. Let’s start with Cancer. Compared to those who had ‘Low’ lifestyle scores, those with ‘Ideal’ scores were 27% less likely to be diagnosed with cancer in the next ten years. These are NCD’s.

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Cancer Dementia Diabetes Cardiovascular Disease 97

HCPLive

OCTOBER 17, 2024

A new prospective study discovered predictors for mortality among patients with sepsis admitted to the emergency department, including age, history of cancer, and dementia.

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Dementia Cancer 59

Dr. Paddy Barrett

SEPTEMBER 13, 2024

Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. The further along the line of insulin resistance you sit, the higher your risk of all the leading causes of death, including heart disease, dementia and many cancers 5.

Risk Factors 106

Risk Factors Heart Disease Dementia Diabetes 106

European Journal of Heart Failure

FEBRUARY 11, 2025

The median time between comorbidity and HF diagnoses ranged from depression preceding HF by 10.7years to dementia proceeding HF by 0.7years; all comorbidities presented earlier in women. Atrial fibrillation/flutter was the commonest disease to immediately precede HF, followed by hypertension, cancer, myocardial infarction and osteoarthritis.

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Heart Failure Myocardial Infarction Cancer Atrial Fibrillation 40

European Journal of Heart Failure

DECEMBER 22, 2023

The highest risk was associated with dementia (hazard ratio [HR] 1.55, 95% confidence interval [CI] 1.45-1.65), CAD and valvular heart disease were associated with a higher risk of all-cause and CV mortality, but not non-CV mortality, whereas cancer and muscolo-skeletal disease increased the risk of non-CV mortality.

Heart Failure 40

Heart Failure Coronary Artery Disease Kidney Disease Dementia 40

Stroke Journal

DECEMBER 8, 2023

In 2013, stroke was the sixth most common primary diagnosis for Medicare hospice, while in 2019 it was the third most common, surpassed only by cancer and dementia. The number of stroke deaths in the United States in individuals aged ≥65 years also increased from 109 602 in 2013 to 129 193 in 2019 (17.9% P<0.001).

Medicare 40

Medicare Strokes Stroke Dementia 40

Dr. Paddy Barrett

AUGUST 15, 2023

Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. Insulin resistance is unlikely to be the primary causal factor for these conditions but is likely to be a major accelerant. Subscribe now Take cardiovascular disease, for example.

Blood Pressure 52

Blood Pressure Risk Factors Diabetes Cholesterol 52

Dr. Paddy Barrett

MAY 3, 2024

For those who have optimised their cardiovascular risk, their future risk of dementia and many cancers is also likely to reduce. If you get these factors right, you also considerably decrease your future risk of the other leading causes of death. Again, there are no guarantees here, but we can seriously tilt the odds in our favour.

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Heart attacks Heart Attack Blood Pressure Risk Factors 105

Physiologically Speaking

FEBRUARY 26, 2024

They also don’t seem to get dementia and Alzheimer’s (the fifth leading cause of death worldwide). Even cancer is rare. Tsimane hearts appeared, on average, 30 years younger than those of the average American. Another study found that they don’t get diabetes and kidney diseases (the ninth leading cause of death).

Diet 52

Diet Cardiovascular Disease Exercise Research 52

Dr. Paddy Barrett

MARCH 12, 2024

Improved levels of mitochondria efficiency are linked to lower rates of the major medical conditions likely to cause early death, namely, cardiovascular disease, cancer and dementia 2. High aerobic fitness levels, as measured by V02, are consistently linked to a longer life 1.

Exercise 98

Exercise Dementia Cancer Cardiovascular Disease 98

Dr. Paddy Barrett

MARCH 29, 2024

To most people's surprise, the leading causes of death are still heart disease and cancer. With cardiovascular disease killing about 25% more people every year than cancer. In the USA, cancer is now the leading cause of death in this age bracket. In the USA, cancer is now the leading cause of death in this age bracket.

Cancer 106

Cancer Heart Disease Risk Factors Cardiovascular Disease 106

Dr. Paddy Barrett

FEBRUARY 28, 2025

Cognitive Performance & Dementia. There is also mechanistic data to support its role in preventing dementia, but for now, this is more speculative 10. Evidence suggests that supplementing with creatine leads to greater total sleep duration on training days 8. 2014 Jun;127(6):547-53. Open Access J. Sports Med. 8, 213–226.

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Blood Pressure Dementia Quality of Life Webinar 83

Dr. Malcolm Kendrick

OCTOBER 30, 2024

Such support is provided by a number of government institutions and charities, including the Medical Research Council, National Institute for Health and Care Research, Department of Health and Social Care, British Heart Foundation, Cancer Research UK and Wellcome. I don’t think so. I have read some utter bollocks in my life.

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Cholesterol Article Research Diet 145

Dr. Paddy Barrett

MARCH 14, 2025

If you have reduced your risk of heart disease and cancer as you age, other threats rise to the surface. A critical component of healthy ageing is the maintenance of cognitive capacity and avoidance of dementia. Muscle power may also play a role in the prevention or progression of dementia. Fall Prevention.

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Dementia Biomarkers Cancer Exercise 114