Physiologically Speaking

SEPTEMBER 20, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. What physiological mechanisms make moderate to high levels of activity so favorable, especially in our modern environment? This week, I’m sharing one of my favorite articles I’ve ever written.

Exercise 113

Exercise Physiology Blood Pressure Obesity 113

Dr. Paddy Barrett

AUGUST 23, 2024

While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. Let’s start with the most basic measures and then examine increasingly complex ones.

Exercise 111

Exercise Dementia Cancer Chronic Disease 111

Physiologically Speaking

OCTOBER 9, 2024

Both lactate and BHB naturally increase in response to physiological stresses—lactate during intense exercise and BHB during prolonged fasting or low-carbohydrate diets. Physiologically Speaking is a reader-supported publication. LaKe is an ester composed of (S)-lactate and (R)-1,3-butanediol, a precursor to BHB.

Exercise 74

Exercise Physiology Diet Obesity 74

Dr. Paddy Barrett

OCTOBER 24, 2023

Not everyone who meets the criteria for metabolic syndrome will become diabetic, but falling into this category means you share much of the same underlying physiology. Share Why you die earlier is likely down to the earlier onset of the two major diseases that are the leading causes of death worldwide: Cardiovascular Disease Cancer.

Diabetes 52

Diabetes Cancer Exercise Cardiovascular Disease 52