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Long-term Survivors of Childhood Cancer at Higher Risk of Death Following Heart Issues; Threshold for Treating Risk Factors Should be Lower

DAIC

The findings – published this week in the Journal of the American College of Cardiology — could fuel advocacy for a paradigm shift in clinical heart health guidelines to address cardiovascular risk factors at an earlier age in childhood cancer survivors. “We Wendy Bottinor, MD.

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Study Finds Air Pollution Can Increase Cardiovascular Risk for Cancer Patients

DAIC

Getty Images milla1cf Wed, 06/19/2024 - 20:54 June 19, 2024 — Modern therapies have extended the lives of many cancer patients; however, survivors often live with chronic health conditions, including cardiovascular disease. The new study was motivated by a need to fill that gap, Rao said. They found that exposure to PM2.5,

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Features of trastuzumab-related cardiac dysfunction: deformation analysis outside left ventricular global longitudinal strain

Frontiers in Cardiovascular Medicine

Background Cancer therapy-related cardiac dysfunction due to trastuzumab has been well-known for many years, and echocardiographic surveillance is recommended every 3 months in patients undergoing trastuzumab treatment, irrespective of the baseline cardiotoxicity risk. Results Twelve (10.9%) patients had asymptomatic CTRCD.

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Burden and prognostic impact of cardiovascular disease in patients with cancer

Heart BMJ

The number of patients at the intersection of cancer and cardiovascular disease (CVD) is increasing, reflecting ageing global populations, rising burden of shared cardiometabolic risk factors, and improved cancer survival. Many cancer treatments carry a risk of cardiotoxicity.

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Cardiotoxicity of adjuvant chemotherapy with trastuzumab: a Japanese claim-based data analysis

Open Heart

Objective Adjuvant chemotherapy with trastuzumab improves the postoperative life expectancy of women with early-stage breast cancer. Women with breast cancer who underwent initial surgery were included. Although trastuzumab is reportedly cardiotoxic, quantification based on real-world evidence is lacking.